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Tight junction protein

Tight Junction Protein Occludin Is a Porcine Epidemic Diarrhea Virus Entry Factor

Tight Junction Protein Occludin Is a Porcine Epidemic Diarrhea Virus Entry Factor

... spike protein to the cellular receptor porcine APN, followed by the entry process (17, 18, ...the tight junction protein occludin contrib- utes to PEDV infection and acts as an entry ...the ...

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Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action

Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action

... occludin protein expression significantly in rat lungs, while low VT just reduced occludin expression slightly (p < ...of tight junctions, decreased integrity of the alveolar membrane, and increased ...

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Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro

Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro

... this would lead to a lower DEP burden per cell. MDM which are positioned at the apical side of the epithelium [15,16,46] might phagocyte the main amount of depos- ited DEP, thus the DEP load to the EC layer in the triple ...

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Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model

Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model

... in tight junction protein expression and composition of microflora contribute to this ...permeability, tight junction protein expression, and fecal bacteria al- teration were ...

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Comparison of Subtyping Approaches and the Underlying Drivers of Microbial Signatures for Chronic Rhinosinusitis

Comparison of Subtyping Approaches and the Underlying Drivers of Microbial Signatures for Chronic Rhinosinusitis

... measured tight junction proteins in this study, only ZO-1 was signifi- cantly downregulated in DC2 relative to the expression in ...the tight junction complex (30, ...of tight ...

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Role of ClC-2 and MAPK in Gastric Barrier Function.

Role of ClC-2 and MAPK in Gastric Barrier Function.

... paracellular tight junctions in order to prevent entry of protons and ...of tight junction protein occludin in both in vivo acid injury in pig gastric mucosa as well as in vitro NSAID injury ...

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Bacteroides fragilis Strain ZY-312 Defense against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and in a Neonatal Rat Model

Bacteroides fragilis Strain ZY-312 Defense against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and in a Neonatal Rat Model

... of tight junction proteins in Caco-2 mono- ...detecting tight junction protein ...ZO-1 protein expression observed in the Caco-2 monolayers ...(OCLN) protein expression ...

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Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

... mediate tight junction changes that lead to BBB dysfunction (32, 33) through their proteolytic activity for extracellular matrix and cleavage of tight junction proteins (reviewed in reference ...

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Identification of the first large deletion in the CLDN16 gene in a patient with FHHNC and late-onset of chronic kidney disease: case report

Identification of the first large deletion in the CLDN16 gene in a patient with FHHNC and late-onset of chronic kidney disease: case report

... the tight junction protein claudin-16; CLDN19 : Gene that encodes the tight junction protein claudin-19; Cnnm2: Cyclin M2; FHHNC: Familial hypomagnesaemia with hypercalciuria and ...

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Regulation of tight junction barrier function by phospholipase C

Regulation of tight junction barrier function by phospholipase C

... first tight junction protein identified, it is the claudin family of proteins that are believed to constitute the primary physical components of tight junctions 40, 41 ...between tight ...

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Bacterial induction of Snail1 contributes to blood brain barrier disruption

Bacterial induction of Snail1 contributes to blood brain barrier disruption

... of tight junction ...models. Tight junction components ZO-1, claudin 5, and occludin were decreased at both the transcript and protein levels in hBMECs following GBS infection, and this ...

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243.full.pdf

243.full.pdf

... ZO-1 is the founding member of the ZO family that also includes ZO-2 and ZO-3 (also known as TJP2 and TJP3, respectively). Each of these proteins contains multiple domains with numerous known and putative binding ...

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Blood brain barrier response in the context of sports related TBI

Blood brain barrier response in the context of sports related TBI

... Within the claudin family of proteins, 24 members have been identified (Tsukita, Furuse & Itoh, 2001). Members of the family share common characteristics such as molecular masses between 20-27 kDa, four ...

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Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis

Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis

... intracellular protein fluorescence was quantified as a percentage of the total fluorescence ⫾ the SEM in a sample population of 10 cells, where each circle represents an individual ...biotinylated protein ...

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Regulation of the Intestinal Barrier in Digestive Disease.

Regulation of the Intestinal Barrier in Digestive Disease.

... the tight junction was initially determined by electron microscopic visualization, with identification of regions where the outer leaflets of plasma membranes from adjacent cells appeared to fuse together ...

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HIV 1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study

HIV 1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study

... TJs: tight junctions; oBRB: outer blood-retina barrier; DMEM: Dulbecco's modified Eagle's medium; FBS: fetal bovine serum; PBS: phosphate-buff- ered saline; BSA: bovine serum albumin; DMSO: dimethyl sulfoxide; ...

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Role of tight junction proteins in gastroesophageal reflux disease

Role of tight junction proteins in gastroesophageal reflux disease

... of tight junction-related molecules in various cell ...increased tight junction per- meability ...several tight junction-related proteins (Claudin-1, Occludin, JAM-1, ZO-1) [57] ...

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The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

... cDNA oligonucleotides containing the sequence corresponding to nucleotides 1412 to 1430 of human occludin cDNA (GenBank accession NM_002538) were annealed and inserted between the BglII and HindIII sites of pSUPER.retro- ...

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Claudin-19 Expression at the Neuromuscular Junction.

Claudin-19 Expression at the Neuromuscular Junction.

... neuromuscular junction; however, only endplates satisfying the following two conditions were included: (1) only neuromuscular junctions near the surface of the muscle were analyzed, and (2) neuromuscular junctions ...

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Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

... Table S1), PHGDH was found to interact with the eukaryotic translation initiation factor 4A1 (eIF4A1) (Fig. 4a and b). EIF4A is one of the three subunits in eIF4F complex, which also contains eIF4E and eIF4G. In the ...

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