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Tight junction proteins

Original Article Somatostatin regulates tight junction proteins expression in colitis mice

Original Article Somatostatin regulates tight junction proteins expression in colitis mice

... Multiple proteins that form the tight junction have been identified, including transmembrane proteins of occludin family, claudin family, zona occludens (ZOs), the junction adhesion ...

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Original Article Tight junction proteins and gap junction proteins play important roles in high fat dietary atherosclerosis pathogenesis

Original Article Tight junction proteins and gap junction proteins play important roles in high fat dietary atherosclerosis pathogenesis

... Gap junction (GJ), communication links, refers to the connection between two adjacent ...gap junction intercellular space connection communication (GJIC) ...gap junction, but form a tightly bunched ...

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Sheep rumen and omasum primary cultures and source epithelia: barrier function aligns with expression of tight junction proteins

Sheep rumen and omasum primary cultures and source epithelia: barrier function aligns with expression of tight junction proteins

... In the present study, we introduce a new method for the isolation and cultivation of epithelial cells from the rumen and the omasum. Upon reaching confluence, cultured cells developed high values of TER, indicating the ...

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Cinnamicaldehyde regulates the expression of tight junction proteins and amino acid transporters in intestinal porcine epithelial cells

Cinnamicaldehyde regulates the expression of tight junction proteins and amino acid transporters in intestinal porcine epithelial cells

... TJ proteins in intestinal ...family proteins and ZO family proteins, play a crucial role in establishing cell–cell contacts and maintaining paracellular perme- ability [36, ...family proteins ...

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A lethal fungal pathogen directly alters tight junction proteins in the skin of a susceptible amphibian

A lethal fungal pathogen directly alters tight junction proteins in the skin of a susceptible amphibian

... Chasiotis and Kelly, 2009; Chang et al., 2010; Saharinen et al., 2010; Yamagishi et al., 2010; Baltzegar et al., 2013; Sun et al., 2015). In addition, the majority of these genes have been identified in the strictly ...

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Expression of Claudin Tight Junction Proteins in Response to Varying Environmental and Physiological Conditions.

Expression of Claudin Tight Junction Proteins in Response to Varying Environmental and Physiological Conditions.

... of tight junctional organization, the number and activity of the various channels, transporters, and pumps on transcellular pathways may also change (Evans et ...

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Developmental Profile of Claudin-3, Claudin-5, and Claudin-16 Tight Junction Proteins in the Chick Intestine.

Developmental Profile of Claudin-3, Claudin-5, and Claudin-16 Tight Junction Proteins in the Chick Intestine.

... transcellular proteins, and ...membrane proteins, which might be a channel or a transporter, and membrane lipids can diffuse laterally in the cell ...these proteins and lipids from basolateral to ...

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The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus

The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus

... In this report, we confirmed that the tight junction protein claudin-1 is an HCV entry cofactor and extended this obser- vation to claudin-6 and claudin-9. While our manuscript was under review, a similar ...

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Role of tight junction proteins in gastroesophageal reflux disease

Role of tight junction proteins in gastroesophageal reflux disease

... corresponding proteins in both dis- eases seem to be of limited relevance to the mucosal integrity and ...these tight junction-related molecules im most gastrointestinal tissues ...5 tight ...

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Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

... including: tight junctions; adherens junctions; and desmosomes ...cated tight junctions perform a fundamental role in regu- lating solute transport across the airway epithelium [5] by restricting ...

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Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model

Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model

... in tight junction proteins, we conducted Western blotting using colon ...epithelial tight junctions of DSS- treated mice was paralleled by quantitatively reduced protein expression ...existing ...

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Host responses to Clostridium perfringens challenge in a chicken model of chronic stress

Host responses to Clostridium perfringens challenge in a chicken model of chronic stress

... Therefore, we chose to exogenously administer CORT to birds to achieve consistently elevated levels of CORT [20]. This allows for the elucidation of how physiological stress affects the host in a prescribed manner. We ...

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Claudin 5: Gatekeeper of neurological function

Claudin 5: Gatekeeper of neurological function

... Dynamic tight junction remodelling in ...of tight junction proteins leads to immune cell entry to the central nervous system ...plasma-derived proteins such as fibrinogen, ...

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Original Article Tightness comparison of ECV304 cells grown on two different types of transwell inserts

Original Article Tightness comparison of ECV304 cells grown on two different types of transwell inserts

... interendothelial tight junction is the key feature of the BBB, and it forms a restrictive barrier for paracellular ...of tight junction proteins occludin, claudin-5 and ZO-1 in ECV304 ...

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Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

... In our experiments, rosiglitazone increased endothelial cell permeability and suppressed tight junction proteins as well as migration, which occurred through the Akt dependent pathway. Increased ...

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Pigment Epithelium-Derived Factor (PEDF) Peptide Eye Drops Reduce Inflammation, Cell Death and Vascular Leakage in Diabetic Retinopathy in Ins2Akita Mice

Pigment Epithelium-Derived Factor (PEDF) Peptide Eye Drops Reduce Inflammation, Cell Death and Vascular Leakage in Diabetic Retinopathy in Ins2Akita Mice

... of Tight Junction Proteins Because we noted a decrease in vascular leakage in the retina by these PEDF deriv- atives, we examined their effects on ex- pression of two tight junction ...

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Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1G93A mice model of ALS

Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1G93A mice model of ALS

... Inhibition of CXCR4/CXCL12 signaling may also regulate blood-central nervous system-barrier (BCNSB) integrity through tight junction proteins [21]. In human ALS and rodents expressing SOD1 mutations ...

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RETRACTED ARTICLE: Differences in the expression profiles of claudin proteins in human nasopharyngeal carcinoma compared with non-neoplastic mucosa

RETRACTED ARTICLE: Differences in the expression profiles of claudin proteins in human nasopharyngeal carcinoma compared with non-neoplastic mucosa

... claudin proteins were reported to interact with other tight junction proteins and to participate in cell signaling path- ways through a PDZ domain in the C-terminus within the cytoplasm [8, ...

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Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

... involved in inflammatory responses (24, 25). MMP2 is constitutively present in zymogen form throughout the brain and activated upon host response to injury. Activation of MMPs occurs via cleavage by other MMPs or ...

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Myosin Light Chain Kinase Knockout Improves Gut Barrier Function and Confers a Survival Advantage in Polymicrobial Sepsis

Myosin Light Chain Kinase Knockout Improves Gut Barrier Function and Confers a Survival Advantage in Polymicrobial Sepsis

... including tight junction proteins and tight junction–associated proteins, which regulate molecular flux based upon both size and charge ...The tight junction ...

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