Tissue Distribution
Pathogenicity and tissue distribution of grass carp reovirus after intraperitoneal administration
... In this study, grass carp were intraperitoneally inocu- lated (i.p.) with different GCRV strains, and the tissue distribution was analyzed. The GCRV-HZ08 stain was isolated form China’ s Zhejiang province ...
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Pharmacokinetics, tissue distribution, and excretion of zinc oxide nanoparticles
... A tissue distribution study showed accumula- tion of both sizes of ZnO nanoparticles in the liver, lung, and kidney, without any statistically significant association with gender or particle size, even when ...
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Tissue distribution of Epstein-Barr virus genotypes.
... the distribution of genetic variants suggests that the exchange of virus between different geographic regions and between individual hosts may be ...marked tissue distribution for epithelial tissues, ...
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Formulation Tissue Distribution and Pharmacokinetic Evaluation of Salbutamol Sulphate Niosomes
... c) Niosomes behave in-vivo like liposomes, prolonging the circulation of entrapped drug and altering its organ distribution and metabolic stability. Encapsulation of various anti neoplastic agents in these carrier ...
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Tissue Distribution Study of Apocynin By RP-HPLC With UV Detector
... Results The developed HPLC-UV method showed good specificity, precision, accuracy and extraction recovery. The good linearity was achieved within 0.8-32 μg/mL in tissues including heart, liver, spleen, lung, kidney and ...
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<p>Pre-Clinical Pharmacokinetics, Tissue Distribution and Physicochemical Studies of CLBQ14, a Novel Methionine Aminopeptidase Inhibitor for the Treatment of Infectious Diseases</p>
... CLBQ14, a derivative of 8-hydroxyquinoline has been identi fi ed and characterized as an inhibitor of MetAP, a promising new target for the treatment of infectious diseases. In this study, we investigated the physicochem- ...
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Pharmacokinetics, tissue distribution, and metabolites of a polyvinylpyrrolidone-coated norcantharidin chitosan nanoparticle formulation in rats and mice, using LC-MS/MS
... The tissue distribution of NCTD in mice after the intravenous administration of both formulations was ...The distribution of the drug in the liver and bile was notably improved in the PVP–NCTD–NP ...
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Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration
... HPLC was performed on an Agilent 1200 series system (Agilent Technologies, Waldbronn, Germany) equipped with a binary pump (G1312A), a thermostatically controlled column compartment and a UV detector. The separation of ...
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Classification of fibroglandular tissue distribution in the breast based on radiotherapy planning CT
... Tissue distribution patterns have been widely investi- gated on mammograms ...breast tissue texture features with the risk of breast cancer using mammo- grams of 768 ...
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Tissue Distribution of Human α1 Microglobulin
... microglobulin serum was prepared and observed to react monospecifically in gel diffusion to purified a 1 -microglobulin, as well as to normal human serum and urine. Sera from the domestic chicken, mouse, rat, rabbit, ...
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Tissue distribution and early developmental expression patterns of aldolase A, B, and C in grass carp Ctenopharyngodon idellus.
... their distribution is also highest in the liver, low in other organs, and virtually absent in the brain and muscle, while the goldfish aldolase C gene is highly expressed in the brain but undetectable in liver and ...
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Tissue Distribution and Uptake of Endogenous Lipoprotein Triglycerides in the Rat
... labeled triglycerides, 3 the in vitro uptake of these endogenously formed triglycerides by adipose tissue, 4 the possible influence of the liver on peripheral tissue uptake of endogenous[r] ...
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Engineered nanomaterial uptake and tissue distribution: from cell to organism
... Abstract: Improved understanding of interactions between nanoparticles and biological systems is needed to develop safety standards and to design new generations of nanomaterials. This article reviews the molecular ...
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Tissue distribution of beta 3 adrenergic receptor mRNA in man
... distribution correlated with that of the cognate receptors established by pharmacological studies. beta 3-AR transcripts were abundant in infant perirenal brown adipose tissue, characterized by the presence ...
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Tissue Distribution and Regulation of Plasminogen Activator Inhibitor-1 in Obese Mice
... 6-fold) in PAI-1 mRNA expression observed in the epididymal, subcutaneous, and brown fat of the obese mice (Fig. 2) suggests that the adipose tissue itself may be a significant contribut[r] ...
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The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia
... Tumor necrosis factor (TNF) is a protein hormone implicated in the development of septic shock and other pathologic states. However, complexities inherent in detecting TNF synthesis by individual tissues have left the ...
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Childhood Obesity, Adipose Tissue Distribution, and the Pediatric Practitioner
... ABSTRACT. The prevalence of pediatric obesity is in- creasing in the United States. Sequelae from pediatric obesity are increasingly being seen, and long-term com- plications can be anticipated. Obesity is the most com- ...
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FcgammaRIIIa: Tissue distribution and regulation of expression
... FcyRIIIa is an IgG Fc receptor found on large granular lymphocytes, natural killer cells and macrophages. The addition of anti-FcyRIII monoclonal antibodies to cultured monocytes expressing FcyRIIIa results in the ...
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Characterization of a 120-Kilodalton pre-S-binding protein as a candidate duck hepatitis B virus receptor.
... the tissue distribution of p120, tissue lysates were pre- cleared and incubated with the construct 80-102, and the re- tained proteins were revealed by an SDS-PAGE minigel fol- lowed by Coomassie ...
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Cloning and characterization of the heart muscle isoform of sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) from crayfish
... Little is known about the biological significance of the existence of two SERCA isoforms. All these genes code for two isoforms that originate by a similar alternative splicing mechanism, but the C-terminal extensions ...
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