tissue repair
Tissue repair genes: the TiRe database and its implication for skin wound healing
... TiRe is continuously updated and developed. In the next build we aim to include: (i) gene/protein expression data from skin wound healing experiments; (ii) genes associated with tissue repair pathologies ...
11
Genetic analysis of murine tissue repair and inflammation
... scar tissue and fibroblasts derived from this tissue (Lee et ...following tissue repair (Sullivan et ...scar tissue in rat wounds (Shah et ...granulation tissue and collagen ...
202
Fibroblast growth factors as tissue repair and regeneration therapeutics.
... Most therapeutics can be considered to manipulate cell communication, with varying aims, such as reducing overactive communication channels in cancer and inflammatory diseases, or increasing particular channels of ...
31
More friend than foe: the emerging role of neutrophils in tissue repair
... triggered repair of lung epithelium via β-catenin signaling ...promote tissue repair, elegantly showing that intercellular transfer of microRNAs (specifically miRNA-223) from neutrophils to pulmonary ...
12
Prostaglandin secreting cells: a portable first aid kit for tissue repair
... Although tissue renewal and homeostasis are probably best understood for intestinal epithelium, many fundamental questions ...sensing tissue injury and initiating the tissue repair response in ...
5
Resident immunity in tissue repair and maintenance: The zebrafish model coming of age
... for tissue repair (Reichenbach and Bringmann, ...the tissue, have a fixed radial morphology which allows them to contact surrounding neurons (Jadhav et ...the tissue for damage and debris ...
12
Allosteric modulation of Beta1 Integrin function induces lung tissue repair
... inherent repair processes other than simply stem cell ...that tissue repair might be achieved by rescueing cells from death by mechanically dampening the signals cells receive from their abnormal ...
16
Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?
... impaired tissue repair, we need to integrate all findings and assess how age-related changes affect ECM homeostasis and tissue repair in the ...lung tissue slices and/or lab-on-a-chip ...
15
Cellular senescence in tissue repair: every cloud has a silver lining
... The finding that cellular senescence has positive roles in wound healing and tissue repair suggest the possibility that it could also play a role in natural regeneration. Although this suggestion has not ...
15
Strategies for Human Adipose Tissue Repair and Regeneration
... promote repair and regen- eration of damaged tissue ...pose tissue needs repair and regenerative approaches not only for the cosmetical impact of absent tissue but also for the ...
15
Polarity during tissue repair, a multiscale problem
... a tissue to restore injured structures in order to re-establish its integrity and continuity is known as tissue ...maintaining tissue homeostasis and function [1,2]. Several mechanisms of ...
6
Investigating the use of curcumin-loaded electrospun filaments for soft tissue repair applications
... In this paper, we have explored a wide range of cur- cumin concentrations incorporated into PDO and assessed the potential of the resulting materials for soft tissue repair applications. PDO is a degradable ...
15
Triggering the regeneration and tissue repair programs
... and Tissue Repair’, which took place in Palma de Mallorca (Spain) and which was co-organized by Enrique Amaya (University of Manchester, UK), Daniel Bachiller (CSIC, Mallorca, Spain), Andras Simon ...
5
Non viral gene delivery systems for tissue repair and regeneration
... Cationic polymers are an advantageous option for cartilage non-viral gene therapy (Table 4). Porous chi- tosan scaffolds with embedded hyaluronic acid/chi- tosan/pDNA nanoparticles encoding TGF-β1 induced DNA controlled ...
20
Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair
... Contrary to other macrophage delivery studies, we performed all experiments on splinted cutaneous wounds. The murine splinted full-thickness excisional wound model is accurate and reproducible, minimiz- es wound ...
15
The role of immunosuppression of mesenchymal stem cells in tissue repair and tumor growth
... acute tissue injuries of the lung[74], heart[75] and ...may repair tissue injury by differentiation into other kinds of cells; on the other hand, as a part of microenvironment, MSCs support the ...
8
Fibroblast growth factors: key players in regeneration and tissue repair
... the tissue adjacent to the insult, as well as progenitor cells recruited from the bone marrow, migrate and proliferate at the wound site in order to rapidly restore the lost tissue (Gurtner et ...in ...
14
Trends in tissue repair and regeneration
... To help identify and test immune modulators of regeneration, Wuhong Pei (Burgess laboratory, NIH, Bethesda, USA) has developed a CRISPR/Cas9-based high-throughput mutagenesis and phenotyping pipeline in zebrafish. Short ...
8
Plasticity of human adipose derived stem cells – relevance to tissue repair
... Post-natally, common sources of MSCs are the bone marrow, adipose tissue and dental pulp. MSCs have been characterized extensively after culture in vitro; however, this procedure selects cells on their ability to ...
10
Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
... gether, these data suggest that blood-borne fibrocytes do not originate from radiosensitive, hematopoietic stem cells but arise instead from either a radioresistant, bone marrow progenit[r] ...
11