TLR—toll-like receptor
B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model
... marrow; TLR, Toll-like receptor; AgR: antigen receptor; BAFF: B cell activation factor of the TNF family; BCR: B cell AgR; TCR: T cell AgR; PRR: pathogen recognition receptor; ...
9
Toll like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease
... cell; TLR: Toll-like receptor; CD: Crohn ’ s disease; UC: ulcerative colitis; DNBS: dinitrobenzene sulfate; DSS: dextran sodium sulfate; PRRs: pattern recognition receptors; GI: ...
8
Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries
... While primarily membrane associated, recently soluble forms of certain TLRs have been identified in body fluids. It has been suggested that the soluble TLRs func- tion to sequester pathogens [22-25]. Recently, we and ...
5
Determination of Genetic Variations of Toll-like Receptor (TLR) 2, 4 and 6 with Next Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein Friesian
... In addition, TLRs also react to damage associated molecular patterns (DAMPs) [2,3] released after cellular damage, and thus play a crucial role in initiating the innate immune response [4]. Genetic variations found in ...
18
Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients
... In this study we comparatively evaluated the influence of chronic smoke exposure on the pattern of TLR2, TLR4 and CD14 expression in human AM and monocytes in COPD patients, smokers and non-smokers. We observed a signif- ...
8
Toll like receptor (TLR) 3 signaling requires the TLR4 interactor with leucine rich repeats (TRIL)
... Toll-like (TLRs) receptors are a family of proteins that act as the primary sensors of microbial products. Many TLRs require accessory molecules in order to recognize these microbial products and initiate ...
23
Immune Activation and Regulation in Simian Immunodeficiency Virus-Plasmodium fragile-Coinfected Rhesus Macaques
... vitro Toll-like receptor (TLR) responses of peripheral blood myeloid dendritic cells (mDC) and monocytes were temporarily associated with acute parasitemic episodes and elevated plasma IL-10 ...
16
TLR5 involvement in attenuated IL 8 production in nuclear decorin silenced oral mucosal dysplastic keratinocytes and squamous cell carcinoma
... Since toll-like receptor (TLR) signalling leads to IL-8 production, we examined here if these receptors played a role in decorin silencing mediated reduction in IL-8 levels in oral mucosal ...
7
Assessment of Lactobacillus gasseri as a Candidate Oral Vaccine Vector
... greater Toll-like receptor activation than dead ...activating Toll-like receptors and whether the dosage of killed bacteria influenced the degree of TLR ...
11
<p>Saturated Fatty Acids in Obesity-Associated Inflammation</p>
... including toll-like receptor (TLR), protein kinase C (PKC), reactive oxygen species (ROS), NOD-like receptors (NLRs), and endoplasmic reticulum (ER) ...
14
Molecular characterization, expression, and functional analysis of chicken TRAF6.
... factor receptor-associated factor (TRAF) family members (TRAF1-7) are intracellular signal transducers involved in inflammation and include immune receptor superfamilies, such as the tumor necrosis factor ...
12
Upregulated genes in toll like receptor (TLR) signaling pathway in periodontitis affected gingival tissues
... the TLR signaling pathway, as well as its constituent ...The TLR signaling pathway is reported to be important in various diseases, including diabetes [23] and cancers [24], in addition to periodonti- tis, ...
7
Lipotoxicity In Obesity: Benefit Of Olive Oil
... insulin receptor substrate 1, CAD, coronary artery diseases, PVD, peripheral vascular disease, NEFA nonesterified fatty acids, TLR-4,Toll-like receptor 4, AMPK activated protein kinase, ...
8
Is There a Relation between Adenosine and Caffeines’ Mechanisms of Action and Toll Like Receptor 4 (TLR 4)?
... Previous studies showed that endogenous adenosine, an anti-inflammatory agent, was released at sites of injury and inflammation thereby decreasing the excessive production of pro-inflammatory cytokines. Caffeine, a ...
7
Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response
... Sialic acid in lipopolysaccharides (LPS) of mucosal pathogens is known to be an important virulence factor. Few strains of Helicobacter pylori express sialyl-Lewis-X and we have reported that human and canine ...
7
Role of polymorphisms of toll like receptor (TLR) 4, TLR9, toll interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children
... of toll-like receptors (TLRs) ...extracellular receptor modules and initiating inflammatory signalling pathways through an intracellular domain ...the TLR- signalling pathway have been ...
8
Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation
... of TLR ligand involved in acti- vation of MSCs, the MSCs become polarized en route for anti-inflammatory and pro-inflammatory phenotype ...repair. Toll- like receptors are a set of an evolutionarily ...
16
Association of Toll-Like Receptor (TLR) Gene Polymorphisms with Asthma: A Review
... IJSRR, 7(3) July – Sep., 2018 Page 1770 (PAMPs) 12,13 . TLR11, TLR12 and TLR 13 only seem to be expressed in mice. The presence of a leucinerich repeat (LRR) domain in their extracellular domain and a TIR domain ...
11
Association of Toll-Like Receptor (TLR) Gene Polymorphisms with Asthma: A Review
... of TLR gene polymorphisms with asthma and related phenotypes are ...of TLR gene polymorphisms with asthma and related phenotypes while some studies have reported no ...in TLR genes with ...
11
Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder
... IL-1β appears to be the cytokine most involved in the quantitative traits and clinical subgroups of ASD (Figure 4). Involvement of IL-1β in the physiopathology of autism is generally supported by several studies ...
12