TNF-α and MCP-1
Original Article Expression of miR-467b in atherosclerosis and its effects on TNF-α and MCP-1 in RAW 264.7 macrophages
... factor α (TNF-α) and monocyte chemoattractant protein-1 (MCP-1) in RAW ...of TNF-α and MCP-1 by RT-qPCR, and analyzed the effects of miR-467b on the ...
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Obese Mexican American Children Have Elevated MCP-1, TNF-α, Monocyte Concentration, and Dyslipidemia
... All antibodies and reagents were pur- chased from eBioscience (San Diego, CA) unless otherwise noted. First, 75- m L aliquots of isolated PBMCs (300 000 cells) were added to 1.2-mL library tubes and incubated with ...
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Original Article The effect of fetuin-A on the release of the inflammatory cytokine HMGB1 from a calcium phosphate crystal-stimulated human macrophage cell line in vitro
... IL-6, TNF-α, and MCP-1 levels were determined by ...for 1 h, the contents of IL-1β, IL-6, TNF-α, and MCP-1 in cell culture supernatant were gradually ...
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Effects of metformin on blood and urine pro-inflammatory mediators in patients with type 2 diabetes
... chain (complex I) and glycerophosphate dehydrogenase. It has been suggested that metformin improves meta- bolic parameters such as hyperglycemia, insulin resist- ance and atherogenic dyslipidemia, thereby reducing ...
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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
... of TNF- α , a pro-inflammatory modulator, and ...chemokine MCP-1 mRNA in the entorhi- nal cortex of 6 month-old 3xTg-AD mice versus the 2 month-old animals (Table ...of TNF- α ...
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Fufang-Zhenzhu-Tiaozhi Capsule reduces restenosis via the downregulation of NF-kappaB and inflammatory factors in rabbits
... VCAM-1, MCP-1 and TNF- α ...IL-6, TNF-α and MCP-1, indi- cating that FTZ targets NF-κB pathway to ameliorate inflammatory cascade in the ...
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The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia
... box 1 (HMGB1, HMGB1 ELISA kit II; Shino-Test Corporation, Tokyo); Krebs von den Lungen-6 (KL-6, Eisai, Tokyo, Japan); receptor for advanced glycation end product (RAGE, R&D Systems; Minneapolis, MN, USA); ...
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The roles of IL-19 and IL-20 in the inflammation of degenerative lumbar spondylolisthesis
... only (hypoxic condition control), and PBS only (normoxic condition control) as the control groups. Total RNA was extracted using Trizol reagent (Life Technologies, Carlsbad, CA) and underwent reverse transcription using ...
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Kinsenoside inhibits the inflammatory mediator release in a type II collagen induced arthritis mouse model by regulating the T cells responses
... of TNF-α, IL-1β, MMP-9, and MCP-1, and increased the gene expression of IL-10 in the inflamed joints of mice with ...of TNF-α, IL-1β and MCP-1 is inhibited and the ...
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Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1
... as TNF-α, IL-1β, IL-6, and chemokines such as cytokine-induced neutrophil chemoattractant (CINC) and MCP-1 are pro- duced by a variety of activated cell types, including endothelial cells, ...
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<p>Resveratrol downregulates TNF-α-induced monocyte chemoattractant protein-1 in primary rat pulmonary artery endothelial cells by P38 mitogen-activated protein kinase signaling</p>
... increase. 1 However, recent studies have shown that the degree of pulmonary occlusion is inconsistent with ...PTE, MCP-1 levels are signi fi cantly augmented around the pulmonary arterial ...
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Effects of Periostracum Cicadae on Cytokines and Apoptosis Regulatory Proteins in IgA Nephropathy Rat Model
... Serum TNF-α, IL-1β, and IL-6 levels significantly decreased in the periostracum cicadae-treated groups compared to the IgAN ...in MCP-1, TLR4, and IgA expression levels and a dose- dependent ...
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Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration
... brain TNF α activated microglia and induced brain monocyte chemo- tactic protein-1(MCP-1) (also known as chemokine (C-C motif ) ligand 2 (CCL2)), IL-1β and TNFα mRNA that led to ...
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Effect of triple viable capsule combined with antibiotic therapy on the inflammatory factors and intestinal mucosal barrier function in patients with spontaneous bacterial peritonitis
... . MCP-1 is an inflammatory factor with chemotactic activity, which can promote the continuous chemotaxis of mononuclear cells to the infected ascites, increase the infiltration of inflammatory cells to the ...
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Vaccaria hypaphorine alleviates lipopolysaccharide induced inflammation via inactivation of NFκB and ERK pathways in Raw 264 7 cells
... of TNF-α, IL-1β, IL-6, IL-10 and MCP-1 ...of TNF-α, IL-1β, IL-6, IL- 10 and MCP-1, and protein expressions of TNF-α, IL-1β, and IL-6 in LPS-treated ...
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Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases
... The increasing prevalence of obesity worldwide is an im- portant epidemiological issue because it is occurring in parallel with the increase in the prevalence of DM and cardiovascular disease (CVD). Moreover, it is well ...
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A role for human brain pericytes in neuroinflammation
... factor-1; MCP-1: monocyte chemotactic protein-1; MHC: major histocompatibility complex; MS: multiple sclerosis; MTG: middle temporal gyrus; NF κ B: nuclear factor light chain enhancer of ...
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Original Article Decreased HCN2 channel expression attenuates neuropathic pain by inhibiting pro-inflammatory reactions and NF-κB activation in mice
... Abstract: Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channel activity plays a crucial role in the progress of peripheral neuropathic pain (PNP). However, the mechanism of HCN2 channels on PNP ...
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Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis
... (TNF α , IL-6, MCP-1) were detected by qPCR and ELISA, respectively; level of reactive oxygen species (ROS) production was examined by the Image-iT LIVE Green ROS detection kit; activation of ...
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<p>Alpha1-Antitrypsin in Urinary Extracellular Vesicles: A Potential Biomarker of Diabetic Kidney Disease Prior to Microalbuminuria</p>
... for TNF- α ; 5 ʹ -GCAATCAA TGCCCCAGTCA-3 ʹ and 5 ʹ -ACACTTGCTGCTGGTGAT TCTT-3 ʹ for MCP-1; 5 ʹ -GAAGGGTACTCAAGGGAAAA TTG-3 ʹ and 5 ʹ -TCACCAGAGCAAAAACTGTGTCT-3 ʹ for α ...
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