TNF-α Induced Apoptosis
Abrogated Thioredoxin System Causes Increased Sensitivity to TNF-α-Induced Apoptosis via Enrichment of p-ERK 1/2 in the Nucleus
... to TNF-α-induced ...against TNF-α-induced ...major apoptosis regulators ...of TNF-α induced apoptosis by controlling nuclear p-ERK1/2 may ...
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Original Article MiR-191 inhibits TNF-α induced apoptosis of ovarian endometriosis and endometrioid carcinoma cells by targeting DAPK1
... bition (Figure 4A). In CRL-11731 cells, miR-191 knockdown, similar as DAPK1 overexpression, could significantly decrease cell survival under TNF treatment. However, DAPK1-mut had stron- ger inhibiting effect than ...
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Original Article MicroRNA-146a-5p inhibits recruitment of macrophages and protects nucleus pulposus cells from TNF-α-induced apoptosis by targeting TRAF6
... Inflammation is thought as a critical player in disc degeneration [19], and there is a signifi- cant increase in immunoreactivity for a variety of pro-inflammatory cytokines, cytokines, in- cluding interferon-γ (IFN-γ), ...
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Inhibition of p38MAPK and CD137 signaling reduce dengue virus induced TNF α secretion and apoptosis
... and apoptosis (Figure ...and apoptosis in DENV-infected HepG2 cells. As DENV induced CD137 expression only 30% of the infected cells (Figure 3B) and expressed at the late stage of infection [13], ...
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Life and death of lymphocytes: a role in immunesenescence
... to TNF-α- induced apoptosis ...to TNF- α -induced apoptosis in young and aged ...increased TNF-α- induced apoptosis as compared to young ...
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Original Article Protective effects of isorhamnetin on apoptosis and inflammation in TNF-α-induced HUVECs injury
... cell apoptosis and inflammation when insult- ed by TNF-α ...with TNF-α for 6 hours. HUVECs apoptosis were detected using flow ...showed TNF-α increased of ...
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Original Article Protease nexin-1 inhibits apoptosis of nucleus pulposus cells induced by TNF-α
... the apoptosis of nucleus pulposus cells and inhibit the expression of extracellular matrix in nucleus pulposus ...inhibited TNF-α induced interver- tebral disc degeneration by inhibiting the ...
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Bildner, Nicole (2002): Characterization of heme oxygenase-1 induction in human endothelial cells. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... as TNF-α (Kiemer et ...against TNF- α-induced apoptosis, a central event in inflammatory diseases, such as atherosclerosis, septic shock and rheumatoid ...
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The Anti-Tumor Effects of M1 Macrophage-Loaded Poly (ethylene glycol) and Gelatin-Based Hydrogels on Hepatocellular Carcinoma
... IL-6, TNF-α and IDO1 upon the exposure to HCC ...hydrogel, TNF-α and nitrite caused HCC cell apoptosis via activating the caspase-3 signaling ...also induced by ...
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The Protective Effect of Adalimumab on Renal Injury in a Model of Abdominal Aorta Cross-Clamping
... that TNF-α, IL-1β, and IL-6 are elevated during I/R and that they are responsible for activation of the apoptosis pathway ...as TNF-α, IL-1β, and ...
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Fuzheng Huayu recipe alleviates hepatic fibrosis via inhibiting TNF α induced hepatocyte apoptosis
... hepatocyte apoptosis is thought to lead to liver dysfunction and damage in a variety of liver dis- eases, and this process may occur during the initiation and/or progression of ...from apoptosis and ne- ...
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TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production
... signaling, apoptosis and necroptosis depending on the cell types and cellular context ...On TNF-α binding, TNF receptor 1 (TNFR1) undergoes a conformational change to form TNFR complex I ...
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Original Article Role of far upstream element binding protein 1 in colonic epithelial disruption during dextran sulphate sodium-induced murine colitis
... that apoptosis of colonic epithelium increased in DSS-induced mice colitis, while the expression of FBP1 decreased and FBP1 translocated to cytoplasm during active inflam- ...was induced by ...
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Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways
... on TNF-α and IFN-γ secretion in CSE-induced Beas-2B ...CSE induced Beas-2B cell apoptosis and ROS pro- duction ...response, apoptosis and oxidative stress (data not ...
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Cathepsin B contributes to TNF α–mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
... the TNF-α/AcD–induced apoptotic cascade in mouse ...directly induced a moderate release of cytochrome c from mitochondria (Figure 7a, compare lanes 1–3 with lane 7) corresponding to about 8% ...
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LiCl induces TNF-α and FasL production, thereby stimulating apoptosis in cancer cells
... strongly induced after LiCl treatment of both p53-negative H1299 and p53- positive U2OS ...LiCl-induced TNF- a by siRNA or inhibition of FasL/Fas interaction by a blocking antibody reduced Caspase-3 ...
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Role of Smac/DIABLO in cancer progression
... or TNF-α with their ...is induced by several different stim- uli like antineoplastic drugs, hypoxia, irradiation, growth factor withdrawal and heat ...cytosolic apoptosis inductor factor-1 ...
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on cell proliferation, apoptosis, and expression of SOST, β-catenin, Collagen II, and MMP13 in rat articular chondrocytes induced by TNF-α in vitro
... in apoptosis and proliferation of chondrocytes require further ...on apoptosis and proliferation of chondrocytes are not fully un- ...with TNF-α to establish the OA model, in vitro. Effects of ...
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β1 adrenoceptor stimulation promotes LPS induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation
... well as JNK, p38 MAPK and CaMKII phosphorylation were also elevated in LPS-challenged mice. On the con- trary, myocardial Bcl-2 protein levels were reduced in LPS- challenged mice at 2 hours after LPS injection. These ...
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adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability
... of α 2 adrenoceptor (α 2 AR) in endothelial ...of α 2 AR on the integrity of human pulmonary microvascular endothelial cells (HPMECs) upon TNF-α-induced endothelial dysfunction, ...
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