Toll-like receptor 2 (TLR2)
The Toll-like Receptor 2 (TLR2)-related Immunopathological Responses in the Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
... the Toll-like receptor 2 (TLR2)-related pathways in the pathogenesis of multiple sclerosis ...by TLR2/TLR2 homodimer and TLR2/TLR1, TLR2/TLR6 and ...
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Original Article Role of Toll-like receptor 2/NF-κB signaling pathway in the pathogenesis of allergic rhinitis
... the toll-like receptor 2 (TLR2)/nuclear factor (NF)-κB signaling pathway in the pathogenesis of allergic rhinitis ...levels, TLR2 mRNA expression levels, and NF-κB protein ...
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Toll-like receptor 2 and type 2 diabetes
... type 2 diabetes and may also participate in the pathogenesis of the ...elevated TLR2 expression on the 3 T3-L1 adipocytes cell lines ...of TLR2 and its related intracellular signaling molecules ...
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Mastitis Increases Mammary mRNA Abundance of β-Defensin 5, Toll-Like-Receptor 2 (TLR2), and TLR4 but Not TLR9 in Cattle
... PRR Toll-like receptor 9 (TLR9) and mapped its precise position on chromosome ...TLR9, TLR2, and TLR4 together with those of  -defensin 5 (BNBD5), an early bactericidal effector molecule of ...
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Toll-like Receptor 2 and 4 (TLR2 and TLR4) Agonists Differentially Regulate Secretory Interleukin-1 Receptor Antagonist Gene Expression in Macrophages
... by TLR2 and TLR4 are not ...and TLR2 ligands, ...the TLR2-specific ...soluble TLR2 agonist from culture filtrates of ...of TLR2 and TLR4 has been provided by the recent identification ...
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Toll-like receptor 2 plays a critical role in pathogenesis of acne vulgaris
... ing TLR2, CD14, and a NF-κB responsive ELAM enhan- cer), but it does not activate NF-κB in BaF3 cells (expressing TLR4, CD14, MD2, and ELAM) (Kim et ...by TLR2 antibody to those cells restores IκB ...
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TLR4 Deters Perfusion Recovery and Upregulates Toll-like Receptor 2 (TLR2) in Ischemic Skeletal Muscle and Endothelial Cells
... The doses used in these experiments have been reported to attenuate murine sepsis (20 μg/mL, final concentration) (25). Rabbit polyclonal IgG served as the negative control (Sigma-Aldrich). Growth factor–reduced Matrigel ...
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Impaired Toll like receptor 2 mediated Th1 and Th17/22 cytokines secretion in human peripheral blood mononuclear cells from patients with atopic dermatitis
... study, TLR2-mediated release of IL-17F was abolished in AD patients while IL- 17A release was not detected in either AD patients or healthy ...However, TLR2 ligands trigger signifi- cantly larger amount of ...
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The Profile of Toll-like Receptor 2 (TLR2), TLR4 and Their Cytosolic Downstream Signaling Pathway in Common Variable Immunodeficiency (CVID) Patients
... of TLR2 and TLR4 or the higher responsiveness to their ligands are established in the development of autoimmune diseases such as rheumatoid arteritis (RA), systemic lupus erythematosus (SLE), Systematic Sclerosis ...
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Toll like receptor 2 (TLR2) plays a role in controlling cutaneous leishmaniasis in vivo, but does not require activation by parasite lipophosphoglycan
... for TLR2 ac- tivation ...activate TLR2, as shown by other studies comparing LPG isolated from different Leishmania species ...through TLR2 and mannose receptor and enhance protective Th1 ...
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Association between Toll Like Receptor 4 (Thr399Ile and Asp299Gly), Toll Like Receptor 2 196 174 Deletion Polymorphisms with cryptosporidiosis
... and TLR2 196 to 174 del polymorphisms, using previously described primers and conditions [12] ...of TLR2 196_174 del polymorphism, band of 286 bp size denoted wild type, 264 bp homozygous and both together ...
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Arg753gln and Arg677 Trp Polymorphisms of Toll-Like Receptor 2 In Acute Apical Abscess
... The receptor is highly expressed on the surface of a variety of immune cells [14-17] and it inter- acts effectively with other TLRs to recognize various microbial ...TLR-6, TLR2 can recruit nuclear Factor ...
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Modulation of atherosclerosis in mice by Toll like receptor 2
... Measurement of aortic atherosclerosis in Pam3-exposed mice. (A) Aortic atherosclerosis expressed as a fraction of total area after 12 weeks of an HFD and weekly i.p. injections of vehicle (veh) or Pam3 in female Ldlr –/– ...
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Toll like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis
... of TLR2 on migrational and invasive mechanisms in ...of TLR2 induces RASFC mi- gration, invasion and induction of ...that TLR2-induced migration/invasion is partly medi- ated by β1 integrin and ...
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Expression profiles of genes involved in TLRs and NLRs signaling pathways of water buffaloes infected with Fasciola gigantica
... TLR1 Toll-like receptor 1 TLR2 Toll-like receptor 2 TLR3 Toll-like receptor 3 TLR4 Toll-like receptor 4 TLR5 ...
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HIV-1 Reactivation Induced by the Periodontal Pathogens Fusobacterium nucleatum and Porphyromonas gingivalis Involves Toll-Like Receptor 4 and 9 Activation in Monocytes/Macrophages
... Since Toll-like receptor 2 (TLR2), TLR4, and TLR9 activation have been involved in HIV-1 recrudescence, we sought to determine the role of these TLRs in HIV-1 reactivation induced by ...
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Glucose-Based Peritoneal Dialysis Fluids Downregulate Toll-Like Receptors and Trigger Hyporesponsiveness to Pathogen-Associated Molecular Patterns in Human Peritoneal Mesothelial Cells
... of Toll-like receptor 2 (TLR2)/TLR4 and subsequent ligand- induced mitogen-activated protein kinase (MAPK) and NF- B signaling and tumor necrosis factor alpha (TNF- ␣ ) and ...
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IL 29 enhances Toll like receptor mediated IL 6 and IL 8 production by the synovial fibroblasts from rheumatoid arthritis patients
... IL-8, TLR2, TLR3 and TLR4 in MH7A cells was determined by real-time ...of 2× SYBR Green Master Mix, 1 μl of 10 μM primers and 1 μl of cDNA to a total volume of 20 ...IL-8, TLR2, TLR3, TLR4 and GAPDH ...
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Bats and their endoparasites : characterising pipistrelle infections and toll like receptor (TLR2 and TLR4) gene variations
... to TLR2 variability in the bats, the most striking observation was that a small number of pipistrelles displayed heterozygosity and interestingly, there was statistical support for this group of bats (n = 7) ...
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Toll like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study
... Children aged three-12 years were recruited for a study assessing complications of cerebral malaria, which was conducted at Mulago Hospital in Kampala, Uganda [20]. Eighty-five children with cerebral malaria (CM) and 76 ...
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