TP53 codon 72 polymorphism
RESEARCH ARTICLE Association of TP53 codon 72 polymorphism in women suffering from endometriosis from Lahore, Pakistan
... The present study involved the investigation of genotype and allele frequencies of TP53 codon 72 polymorphism in patients of endometriosis and healthy women. It was found that pro/pro ...
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TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma
... Low-grade gliomas (LGGs) and glioneuronal tumours are the most common brain tumours in childhood and adolescence. Among them, pilocytic astrocytomas (PAs) are the predominant pathological subtype, followed by mixed ...
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Polymorphisms of TP53 codon 72 with breast carcinoma risk: evidence from 12226 cases and 10782 controls
... A previous meta-analysis conducted by Koushik et al. [61] regarding cervical cancer suggests that homozygote Arg/ Arg genotype increases susceptibility to both squamous cell carcinoma and adenocarcinoma. While another ...
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Association of TP53 gene codon 72 polymorphism with endometriosis risk in Isfahan
... It have showed that structural alterations in the p53 protein can outcome from a single amino acid exchange that causes improper protein action and defeat of role because of an incapability to cooperate with further ...
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Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis
... on TP53 genes was freely available in Onco- mine online ...that TP53 was associated with colorectal cancers based on TCGA datasets (Figure ...The TP53 mRNA expression was shown in different types of ...
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Frequency of p53 Gene Codon 72 Polymorphisms in Women with Breast Cancer in Iran
... with TP53 gene polymorphism (pro/pro) showed poor prognosis and survival in breast [9, 10], ovarian [11], lung [12], head and neck cancers [12], as well as esophageal squamous cell carcinoma ...length ...
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Association between <em>TP53</em> gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population
... the TP53 gene so far, supporting its highly polymorphic ...C.G) polymorphism. This polymorphism is located in the exon 4 of the TP53 gene and can lead to the replacement of arginine (Arg) with ...
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Association of TP53codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients
... of TP53 codon 72 was signif- icantly associated with poor DFS by Kaplan-Meier analysis, as shown in Figure 1b (P = ...of TP53 codon 72 is an independent prognostic marker in ...
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No association of TP53 codon 72 and intron 3 16-bp duplication polymorphisms with breast cancer risk in Chinese Han women: new evidence from a population-based case–control investigation
... duplication polymorphism, the homozygous Del/Del was the most frequent genotype in both groups and its distribution frequency was signifi- cantly higher (approximately eightfold) than that of the heterozygous ...
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... Arg72Pro polymorphism (rs1042522) at codon 72 in exon 4 of the TP53 gene have reported an association of the Arg allele with increased risks for colorectal, breast and lung cancers and the Pro ...
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Genotyping of P53 Gene Exon 4 Codon 72 in Sudanese Patients with Myelogenous Leukaemias
... Background: TP53 gene, exon 4, codon 72 Arginine (Arg)/Proline (Pro) polymorphism has been reported to be associated with the risk of many types of ...P53 codon 72 Arg/Pro ...
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Association of p53 codon 72 Arg>Pro polymorphism and risk of cancer in Iranian population: A systematic review and meta-analysis
... c 72 G>C polymorphism with an increased or decreased cancer ...p53 Codon 72 G>C polymorphism is not a significant cause of cancer odds among the Iranian ...Arg/Arg) codon ...
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Review Article p53 codon 72 polymorphism is associated with human papillomavirus-related esophageal cancer risk: a meta-analysis
... Two investigators (ZZ and XY) independently reviewed and extracted information from all eli- gible publications in accordance with the selec- tion criteria. Disagreement was resolved by a third independent reviewer (JL) ...
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Genetic polymorphism among some wheat genotypes as revealed by RAPD and SCOT analysis
... genetic polymorphism among seven wheat cultivars using SCoT (Start Codon Targeted polymorphism) and RAPD (Random Amplified Polymorphic DNA) was ...higher polymorphism, where obtained 25 bands ...
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P53 codon 11, 72, and 248 gene polymorphisms in endometriosis
... Most cancer-related mutations of p53 are clustered in the four so-called 'hot spots', codon 175, 248, 273 and 281/282 [32]. Numerous reports presented the correlation statuses of p53 codon 248 ...
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POLYMORPHISMS IN CELL CYCLE REGULATOR GENE P27KIP1 AND P16INK4A AND LUNG CANCER RISK IN A BANGLADESHI POPULATION
... a polymorphism, which has been reported in lung carcinogenesis in central Europe [32], 8% of the Jewish population [43], 4% of the population in Utah [44] and 5% in the UK population [45] and also in a population ...
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Genetic, Environmental and Clinical Factors Related to Treatment Failure of Cervical Precancerous Lesions in a Cohort of Brazilian Women
... After agreeing on signing the informed consent, all women were invited to answer a questionnaire with epidemiologic, environmental and clinical information applied by two trained registered nurses, and the patient was ...
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Analysis of Polymorphism rs1042522 in TP53 Gene in the Mothers of Twins and of Singletons: A Population-Based Study in Rio Grande do Sul, Brazil
... of polymorphism rs1042522 in TP53 gene was more frequent in the mothers of twins than in the mothers of singletons in Candido Godoi, a small village in South Brazil (Tagliani-Ribeiro et ...
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Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina
... p53 codon 72 polymorphism (Arg, Pro or Arg/Pro) were deter- mined in the patients with benign and malignant tumors in order to evaluate the possibility of increased cancer sus- ceptibility associated ...
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Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance
... characterize polymorphism and immune selection in population-derived sequences of integrase, and to map areas of potential overlap with integrase inhibitor associated ...
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