Transcription Factor A Mitochondrial
p53 increase mitochondrial copy number via up-regulation of mitochondrial transcription factor A in colorectal cancer
... In colorectal cancer, no study has been carried out discovering the relationship among p53, mitochondrial transcription factor A (TFAM) expression and change of mitochondrial DNA (mtDNA) copy ...
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Human Mitochondrial Transcription Factor A Reduction and Mitochondrial Dysfunction in Hashimoto’s Hypothyroid Myopathy
... Background: Mitochondrial changes have been described in muscle tissue in acquired ...of mitochondrial respiratory function, the mito- chondrial transcription factor A (h-mtTFA) has been pro- ...
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Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways
... long-lived mitochondrial mutants in Caenorhabditis elegans by modulating the levels of ATFS-1, the central transcription factor that mediates the ...long-lived mitochondrial mutant nuo-6 ...
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Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A
... The mitochondrial transcription factor A (TFAm), a protein that regulates mitochondrial transcription, is abundant in these ...for mitochondrial DnA compaction, yet the exact ...
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Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries
... of mitochondrial biogene- sis have been identified (reviewed in reference 76), to our knowl- edge, there is no transcription factor yet known to specifically regulate the genes encoding ...
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Re-assessment of YAP1 and MCR1 contributions to inhibitor tolerance in robust engineered Saccharomyces cerevisiae fermenting undetoxified lignocellulosic hydrolysate
... the transcription factor (YAP1) and the mitochondrial NADH-cytochrome b5 reductase (MCR1), either alone or in combination, in an already robust and xylose-consuming industrial strain of ...
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Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
... hyperglycemia-induced mitochondrial superoxide overproduction increases O- linked N-acetylglucosamine modification and decreases O-linked phosphorylation of the transcription factor Sp1, the effect ...
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Controlling muscle mitochondrial content
... distinct transcription factors, although each NHR retains sufficient structural homology to be recognized as a member of the family that arose more than 400 million years ...these transcription factors, ...
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PGC 1 coactivators: inducible regulators of energy metabolism in health and disease
... For example, PGC-1α coactivates members of the PPAR nuclear receptor transcription factor family, to activate the expression of genes involved in mitochondrial fatty acid oxidation.. The[r] ...
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Mitochondrial Protein in the Nucleus
... nuclear transcription factor mediating senescence and apoptosis, but it also accumulates in the mitochondrial matrix in response to oxidative stress and triggers mitochondrial permeability ...
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Herpesvirus Saimiri STP-A Oncoprotein Utilizes Src Family Protein Tyrosine Kinase and Tumor Necrosis Factor Receptor-Associated Factors To Elicit Cellular Signal Transduction
... STP is considered to be a major viral oncoprotein of HVS since it is not required for viral replication but is required for viral pathogenesis in tissue culture and in primates (13, 14). We previously demonstrated that ...
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Temporal Hierarchy of Gene Expression Mediated by Transcription Factor Binding Affinity and Activation Dynamics
... ABSTRACT Understanding cellular responses to environmental stimuli requires not only the knowledge of specific regulatory components but also the quantitative characterization of the magnitude and timing of regulatory ...
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Curcumin targets the TFEB-lysosome pathway for induction of autophagy
... Lysosomes are acidic organelles containing a wide spectrum of hydrolytic enzyme, including proteases, peptidases, phosphatases, nucleases, glycosidases, sulfatases, and lipases designated for all types of macromolecules ...
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Ch. 11 Cell Communication Notes.ppt
... Figure 11.15 Growth factor Receptor Reception Transduction CYTOPLASM Response Inactive transcription factor Active transcription factor DNA NUCLEUS mRNA Gene Phosphorylation cascade P.. [r] ...
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A Regulatory Circuit Composed of a Transcription Factor, IscR, and a Regulatory RNA, RyhB, Controls Fe S Cluster Delivery
... classical transcription factors to coordinate genetic re- ...a transcription factor, IscR, regulate expression of an essential gene, erpA, in the bacterium ...
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The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect
... The absence of the CPE in the ΔmpkA strain does not result from a lack of transcriptional upregulation of chitin synthase-encoding genes, a mechanism which is thought to mediate protection/resistance to caspofungin ...
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Morosetti, Arianna (2012): The Arabidopsis MTERF protein PAM48 is required for plastid gene expression and development. Dissertation, LMU München: Fakultät für Biologie
... the transcription complexes, which are comprised of mitochondrial RNA polymerase (POLRMT), Tfam - a stimulatory factor that unwinds DNA - and one of the two TFB isoforms (TFB1M or TFB2M) that ...
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A Horizontally Acquired Transcription Factor Coordinates Salmonella Adaptations to Host Microenvironments
... The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate ef- fectors that reprogram host cell functions to benefit infecting Salmonella in the ...These ...
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Hypoxia-Induced Alterations in Skeletal Muscle Cell Respiration and Resveratrol as a Potential Pharmacological Intervention
... The mitochondrial isolation buffer was supplemented with a 10X protease/phosphatase inhibitor on the day of ...the mitochondrial fraction was washed twice by adding 100 µl of cold isolation buffer and ...
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Maintenance of Transcription Translation Coupling by Elongation Factor P
... and transcription, the ribosome enables synthesis of full- length mRNAs by preventing both formation of intrinsic terminator hairpins and loading of the transcription termination fac- tor ...on ...
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