Transcription Factor AP-1
Sirtuin 1 Regulates Hepatitis B Virus Transcription and Replication by Targeting Transcription Factor AP-1
... risk factor for liver cirrhosis and hepatocellular ...targeting transcription factor AP-1. The c-Jun subunit of AP-1 was bound to the HBV core promoter region, as ...
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Activation of transcription factor AP-1 in response to thermal injury in rat small intestine and IEC-6 cells
... the AP-1 complex, supershift experiments were carried out by adding anti- bodies against c-Jun, JunB, JunD, c-Fos and ATF2 to the nuclear extracts from IEC-6 cells exposed heat for 1 ...the ...
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Interactions of the transcription factor AP-1 with the long terminal repeat of different human immunodeficiency virus type 1 strains in Jurkat, glial, and neuronal cells.
... Analysis of the 2 247 to 2 222 LTR region, region D. To identify the proteins contributing to the interaction with LTR region D, detected with the JR-FL and JR-CSF isolates, the synthetic oligonucleotide 5N (Fig. 7) was ...
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Transcription factor AP-1 modulates the activity of the human foamy virus long terminal repeat.
... A The plus strand was end labeled with polynucleotide kinase at the BstEII -571 site of the fragment, incubated with 5 p.g of bacterially expressed c-Jun lane 3 or v-Jun lane 4 or with 5[r] ...
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Upregulation of TRAF 3 by shear stress blocks CD40 mediated endothelial activation
... receptor–associated factor-3 (TRAF-3) as a potent CD40-inhibitory ...tissue factor and blocks DNA-binding activity of the transcription factor AP-1; it thereby prevents ...
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Antioxidant-induced changes of the AP-1 transcription complex are paralleled by a selective suppression of human papillomavirus transcription.
... the transcription factor AP-1 to its cognate recognition site within the viral regulatory ...increased AP-1 binding, normally indispensable for efficient HPV-16 ...
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Regulation of HIV 1 transcription in cells of the monocyte macrophage lineage
... HIV-1 transcription in cells of the mono- cyte-macrophage lineage is a complex process involving the interaction of numerous factors that are expressed in a differentiation-dependent manner and whose ...
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Role of AP-1 transcriptional factor in development of oxidative and nitrosative stress in periodontal tissues during systemic inflammatory response
... by AP-1. Tao X. et al. showed that the AP-1 inhibition by flavonoids from Rosa laevigata is accompanied by a decrease in ROS production and lowering IL-1, IL-6 and TNF-α expression ...
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Original Article Ectopic expression of AP-2α transcription factor suppresses glioma progression
... the transcription factor activator pro- tein-2 (AP-2) family {Britto, 2007 #42} {Britto, 2007 ...#42}. AP-2α binds to CG-rich sequences such as 5’-GCCN 3 GGC, 5’-GCCN 4 GGC and 5’- GCCN 3/4 ...
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The AP 1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field
... The vertebrate heart forms through successive phases of cardiomyocyte differentiation. Initially, cardiomyocytes derived from first heart field (FHF) progenitors assemble the linear heart tube. Thereafter, second heart ...
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YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity.
... an AP-1 motif, which was present on a 221-bp fragment that contained no obvious transcriptional ...The AP-1 motif had previously been shown to activate a thymidine kinase promoter in a ...
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Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor
... the AP-2 ␣ protein, since Rymo’s group suggested the involvement of AP-2 (or an unknown host protein that binds to the AP-2 motif in ED-L1p) by mutagenesis of ED-L1p using reporter assay systems in ...
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Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Requires Cellular Transcription Factor JunD To Upregulate HTLV-1 Antisense Transcription from the 3′ Long Terminal Repeat
... ATF/CREB transcription factors are ubiquitously ex- pressed in mammalian cells (51), the expression of AP-1 tran- scription factors is regulated by the cell activation status (9, 21, ...activate ...
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Regulation of Human Polyomavirus JC Virus Gene Transcription by AP-1 in Glial Cells
... activating transcription factor 1 (AP-1) family of proteins consists of a large number of inducible factors that are implicated in many biological processes, including cellular and ...
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CCAAT/enhancer binding protein β promotes receptor activator of nuclear factor kappa B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis
... medium; AP-1: activator protein-1; ATF-4: activation transcription factor 4; bp: base pairs; C/EBP: CCAAT/enhancer binding protein; ChIP: chromatin immunoprecipitation; DMEM: Dulbecco ’ ...
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Lactogenic differentiation of HC11 cells is not accompanied by downregulation of AP 2 transcription factor genes
... assess AP-2 transcription factor gene expression, HC11 cells were grown under normal conditions (in the pres- ence of EGF) or subjected to differentiation conditions by first culturing to confluency ...
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Redox Regulation of an AP-1-Like Transcription Factor, YapA, in the Fungal Symbiont Epichloë festucae
... colonize the grass host (55), as the natural route of infection through the stigmata and styles of the flowers is a process that is difficult to reproduce under laboratory conditions (67). However, wounding of seedlings ...
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Activation of AP-1-Dependent Transcription by a Truncated Translation Initiation Factor
... initiation factor 3 (eIF3) that has also been reported to interact with subunits of the proteasome and the COP9 ...inessential AP-1 transcription factor ...contained AP-1 ...
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Herpesvirus Saimiri STP-A Oncoprotein Utilizes Src Family Protein Tyrosine Kinase and Tumor Necrosis Factor Receptor-Associated Factors To Elicit Cellular Signal Transduction
... C/EBP, AP-1, SP-1, and the retinoic acid response element ...type 1 Tax and EBV LMP-1 activate NF- 〉 activity to upregulate ICAM-1 expression, which is thought to facilitate ...
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Transregulation of microRNA miR-21 promoter by AP-1 transcription factor in cervical cancer cells
... several transcription factors as pioneer factors that can affect or even cause biological changes required in the initial steps of the transforma- tion, invasion and metastasis cascades ...instance, ...
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