transcription factor AP-2
Transcription factor AP 2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage
... specific transcription factors such as ...that transcription factor AP-2 γ (TFAP2C) functions as a novel upstream regulator of Cdx2 expression and position-dependent HIPPO signaling in ...
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Lactogenic differentiation of HC11 cells is not accompanied by downregulation of AP 2 transcription factor genes
... sustained AP-2 transcript levels, these results clearly demonstrate that lactogenic differentiation of HC11 cells does not fully reflect the in vivo ...of AP-2 transcription ...
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Redox Regulation of an AP-1-Like Transcription Factor, YapA, in the Fungal Symbiont Epichloë festucae
... hydrogen peroxide-inducible genes in Escherichia coli and Salmo- nella enterica serovar Typhimurium (82, 83). Interestingly, nearly all the Yap1 homologs found in filamentous fungi have just a single conserved Cys in the ...
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Direct, Interferon-Independent Activation of the CXCL10 Promoter by NF-κB and Interferon Regulatory Factor 3 during Hepatitis C Virus Infection
... CXCL10 transcription was also significantly de- creased in response to all three treatments after mutation of the proximal ISRE ( ⌬ ISRE; P ⬍ ...⌬ AP-1, ⌬ C/EPB-  1, and ⌬ C/EPB-  2 constructs (P ⬍ ...
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Original Article Ectopic expression of AP-2α transcription factor suppresses glioma progression
... of AP-2α in the development/ progression of glioma has not been fully ...by AP-2α such as those involved in cell proliferation (Hoxa, IGF receptor type I and IGF-binding proteins 3/5) [40-43], cell cycle ...
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Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans
... lyophilized. Total RNA was isolated by Easy-BLUE (iNtRON) and purified with an RNeasy Mini kit (Qiagen). cDNA libraries were constructed with a TruSeq RNA library kit v2 (Illumina) using 1 g total RNA and sequenced ...
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Transregulation of microRNA miR-21 promoter by AP-1 transcription factor in cervical cancer cells
... that AP-1 transcription factor is recruited to AP1D, AP1M, and AP1P sequences in a differential manner to induce the miR-21 promoter in cervical can- cer cells ...of AP-1 in the miR-21 ...
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Identification potential biomarkers in pulmonary tuberculosis and latent infection based on bioinformatics analysis
... Activating transcription factor; ATP1A4 : ATPase, Na+/K+ transporting, alpha 4 polypeptide; BATF : Basic leucine zipper transcription factor, ATF-like; BH: Benjamin and Hochberg; BP: ...
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Role of AP-1 transcriptional factor in development of oxidative and nitrosative stress in periodontal tissues during systemic inflammatory response
... such transcription factor as activator protein 1 (AP-1) in the development of oxidative and nitrosa - tive stress in soft periodontal tissues during chronic systemic inflammatory response ...(O ...
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Sirtuin 1 Regulates Hepatitis B Virus Transcription and Replication by Targeting Transcription Factor AP-1
... (CBP, p300, and PCAF/GCN5) and the histone deacetylases (HDAC1 and SIRT1) are all recruited in vivo onto the cccDNA. These researchers further demonstrated that high recruitment of HDAC1 and SIRT1 onto cccDNA correlated ...
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Transcriptional components of anteroposterior positional information during zebrafish fin regeneration
... Fig. 2. Visualization of AP region-specific transcription factor expression in fin fibroblasts and ...The AP expression characteristics of alx4a:DsRed2 and hand2:EGFP are maintained ...
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Regulation of Tumor Necrosis Factor Alpha Promoter by Human Parvovirus B19 NS1 through Activation of AP-1 and AP-2
... bind AP-1 and AP-2 sites in the TNF- ␣ ...the AP-1 and AP-2 sites could be responsive to NS1 in the regu- lation of the TNF-␣ ...the transcription activity of the TNF-␣ ...
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Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma
... Cells were seeded on coverslips and cultured routinely. Once the cells had reached 70% confluence, they were fixed for 15 min in 4% paraformaldehyde (Beyotime, Shanghai, China). After washing with phosphate-buffered ...
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Activation of transcription factor AP-1 in response to thermal injury in rat small intestine and IEC-6 cells
... apoptosis. AP-1 complex con- sists of homodimers and heterodimers formed by a group of transcription factors, including members of the Jun, Fos, and ATF families ...the transcription factor ...
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Activation of AP-1-Dependent Transcription by a Truncated Translation Initiation Factor
... translation factor, might also act to modulate AP-1-dependent transcription is an intriguing one, but at this stage it is unclear whether the activation of Pap1 by Int6CT represents a normal ...
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Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor
... domain factor (termed D ␣ 1), unidentified host factor (termed D ␣ 2) also binds to the POU domain site within the ED-L1 pro- ...unknown factor and found that a paired box family ...
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Dysfunction of various organelles provokes multiple cell death after quantum dot exposure
... Mitochondrion is the main site of energy production in cells, which functions in oxidative phosphorylation, electron transfer and catabolism. As well, mitochondria are the cellular resources of adenosine triphosphate and ...
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Transcription factors: Are they a real target for future therapeutic strategies?
... suppress cytokine expression at the transcriptional level (83). In regard to therapy there are already specific PPAR-isoform inhibitors and activators available (84). 15-deoxy- Delta(12,14)-PGJ(2) ...
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Cellular oxygen sensing need in CNS function: physiological and pathological implications
... growth factor) β3, the HIF pathway includes responses with adverse effects on cell function by inducing cell-cycle-arrest-specific and proapoptotic proteins such as DEC (defective chorion)-1, BNIP (Bcl2/adenovirus ...
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A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics
... cycle[52], transcription[53], carcinogenesis[54] and virus infec- tion[55, ...gene transcription and DNA replication ...have transcription activation or repression activity [4, 49, ...
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