Transcription factor gata-1
Transactivation of erythroid transcription factor GATA-1 by a myb-ets-containing retrovirus.
... In the present study we demonstrate that ME26 virus infection of FDC-P2 cells also results in enhanced expression of 13-globin and the erythroid-specific transcription factor GATA-1, a p[r] ...
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Transforming growth factor β increases interleukin 13 synthesis via GATA 3 transcription factor in T lymphocytes from patients with systemic sclerosis
... For GATA-3 mRNA, the forward primer was 5′- TGCGGGCTCTA TCACAAAATG-3′ and the reverse primer was 5′- GC ...finally 1 min at 72 °C and 10 min at 72 ...
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The Oxidative Stress Response in Caenorhabditis elegans Requires the GATA Transcription Factor ELT-3 and SKN-1/Nrf2
... Our current interest in studying the mechanisms controlling an organism’s response to oxidizing conditions came about from studying the physiological role of C. elegans BRAP-2. We observed that brap-2(ok1492) worms ...
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Increased Electrophoretic Mobility of Long Type GATA 6 Transcription Factor upon Substitution of Its PEST Sequence
... (Figure 1(b)), the PvuI site between the SphI and NaeI sites of the vector sequence in pTA4-4CTGmAla2 was deleted by digestion with restriction enzymes SphI and NaeI, followed by Klenow enzyme treatment and ...
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Differential expression and functional role of GATA 2, NF E2, and GATA 1 in normal adult hematopoiesis
... the transcription factors GATA-1, GATA-2, and NF-E2 in purified early hematopoietic progenitor cells (HPCs) induced to gradual unilineage erythroid or granulocytic differentiation by growth ...
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Multiple Nuclear Localization Signals Mediate Nuclear Localization of the GATA Transcription Factor AreA
... E ukaryotic transcription factors are synthesized in the cyto- plasm but function in the nucleus to regulate gene expression. This provides a logistical problem for these proteins, as they must be imported into ...
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Members of the GATA Family of Transcription Factors Bind to the U3 Region of Cas-Br-E and Graffi Retroviruses and Transactivate Their Expression
... other GATA elements, especially in regions found protected by DNase I footprinting ...putative GATA sites: one at the 59 end of the LTR (CCATC, nucleotides 14 to 18), present only in Cas-Br-E LTR, and one ...
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Transdifferentiation and remodeling of post embryonic C elegans cells by a single transcription factor
... a GATA transcription factor that regulates terminal intestinal differentiation (Maduro and Rothman, 2002; Sommermann et ...END-1 GATA transcription factor, which specifies ...
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Clinical significance of T bet, GATA 3, and Bcl 6 transcription factor expression in bladder carcinoma
... T-bet, GATA- 3, and Bcl-6, were determined by quantitative real- time reverse-transcriptase PCR ...T-bet, GATA-3, Bcl-6, and L32 genes are described in Table 2, and were from ...
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Cell type specificity of a diffusible inducer is determined by a GATA family transcription factor
... In order to understand how this patterning mechanism operates, great efforts have been made to identify the signalling molecules that regulate it. One such molecule is the chlorinated alkyl phenone DIF- 1 ...
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The Myeloid Transcription Factor GATA-2 Regulates the Viral UL144 Gene during Human Cytomegalovirus Latency in an Isolate-Specific Manner
... for 1 min for 35 ...two GATA-2 sites. Mutagenesis primer pairs were designed for the GATA-2 deletion as follows: forward primer, 5=-GATTACCTATGCTCCTACGGCCTAAGAGGTAGAC-3=, and reverse primer, ...
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The Transcription Factors GATA 1 and GATA 4 Have Opposite Effects on DNA Expression Driven by an Amh Promoter
... putative transcription factor binding elements mutated (Figure 1), were used to drive the expression of a green fluorescent reporter gene (d2EGFP) ...(Figure 1). The role of two potential ...
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A Paradoxical Mutant GATA Factor
... Vertebrate GATA factors are involved in local chromatin alterations (10, 58), but it has not been shown that they are involved in loss of nucleosome postioning in ...vertebrate GATA factor ...
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The Formaldehyde Dehydrogenase SsFdh1 Is Regulated by and Functionally Cooperates with the GATA Transcription Factor SsNsd1 in Sclerotinia sclerotiorum
... the GATA-box DNA in EMSA ...other GATA factors might be involved in the regulation of Ssfdh1 ...the GATA-box upstream of brlA, but loss of flbC or flbD in the absence of nsdD resulted in delayed ...
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Differential Expression of Aspergillus nidulans Ammonium Permease Genes Is Regulated by GATA Transcription Factor AreA
... To assess whether the structurally different MepC protein could function as an ammonium transporter, the effect of overexpression was determined. Multiple copies of mepC (pMA5741) were introduced into the mepA ⌬ meaA ⌬ ...
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483.full.pdf
... (Fig. 1) (Sulston et ...small GATA- type transcription factors, END-1 and END-3, are transcriptionally activated only in the E blastomere (Maduro et ...(Fig. 1), END-1 and END-3 ...
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Role of Gata-4 Transcription Factor Associated With B-Type Natriuretic Peptides in Heart Failure
... peptides with a homologous structure are secreted by heart namely ANP and BNP as shown in (Fig. 1). A third homologous natriuretic peptide, termed CNP, is produced in brain and endothelium, but apparently not in ...
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Cardiac Cells in Regenerative Processes in Patients with Heart Failure Due to Ischaemic Heart Disease
... cell factor. In the adult rat myocardium, c-Kit+ cells are rare (1 per 10,000 myocytes), and heterogeneous, with a minority (7%-10%) expressing early cardiac transcription factors such as ...
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Series Introduction: Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair
... ref. 1 for review), which, in turn, regulate gene transcription to influ- ence cell fate, proliferation, and ...roid transcription factor-1 [TTF-1]), as well as tran- scription ...
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TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1
... the GATA transcription factors Gln3 and Gat1 ...following 1 h of shift to proline or no nitrogen ...⫹ transcription even under rich conditions ...
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