Transforming growth factor-1
Connective tissue growth factor antagonizes transforming growth factor ?1/Smad signalling in renal mesangial cells
... β 1 and the TβRIII may be required for the moderation of signalling ...compounding factor in regulating TGF-β1–TβR binding is the expression of ...β 1 binding compared with other cell types ...
14
Transforming growth factor-β1 gene polymorphism in psoriasis vulgaris
... β 1 was significantly associated with susceptibility to psoriasis (P = ...β 1 gene mutation was significantly more common among patients with positive family history (P = ...
5
Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases.
... regulatory factor with multiple functions, TGF-b1 participates in several important pathophysiological processes, and is currently studied ...tissue growth factor (CTGF) and TGF-b1 levels in hepatic ...
11
Dog mastocytoma cells produce transforming growth factor beta 1
... Transforming growth factor-beta (TGF beta) promotes deposition of extracellular matrix and is associated with fibrotic conditions both in experimental animals and in ...fibroblast growth or ...
8
Lack of transforming growth factor β signaling promotes collective cancer cell invasion through tumor stromal crosstalk
... In ovo tumors were harvested, fixed in 10% neutral buf- fered formalin, paraffin embedded, and sectioned. All immunohistochemistry and immunofluorescence involved blocking via incubation with 3% normal goat serum (Vector ...
18
Post translational processing of proteins implicated in the pathogenesis of Alzheimer's disease
... The APP-751 isoform was shown to be up-regulated and the APP-695 isoform down-regulated in response to neuronal injury in rat brain (Iverfeldt et a l , 1993). It is possible that this effect was mediated via the products ...
262
Development of a two-step protocol for culture expansion of human annulus fibrosus cells with TGF-β1 and FGF-2
... with transforming growth factor (TGF- β 1) and fibroblast growth factor (FGF-2) culture for 14 days: group 1 had no GFs (control group); group 2 received TGF- β 1; ...
10
Expression of epidermal growth factor, transforming growth factor-β1 and adiponectin in nipple aspirate fluid and plasma of pre and post-menopausal women
... Nipple aspirate fluid (NAF) is a rich source of protein postulated to more closely reflect the local breast micro- environment than plasma. Petrakis et al. [1] showed that simply producing NAF doubled a woman’s ...
5
Transforming growth factor beta and breast cancer: Tumor promoting effects of transforming growth factor β
... -induced growth inhibitory responses and extracellular matrix responses may represent distinct processes in certain cell ...TGF-β1-mediated growth inhibition, but enhances the ability of TGF- β 1 to ...
8
An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma
... (IL-1), IL-2, hematopoietic colony-stimulating factors (CSFs), platelet-derived growth factor (PDGF), and transforming growth factor (31 (TGF-j31) each can act as an autocrine growth fac[r] ...
11
Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury
... cell growth (transforming growth factor [TGF]-β1, vascular endothelial growth factor [VEGF] A, insulin-like growth factor [IGF]-1, IL-6, platelet-derived ...
12
Transforming Growth Factor – β and Glioma
... Due to the increasing amount of evidence which suggest that the increase in TGF-β signaling is prominent in malignant tumors, the clinical application of TGF-β is being investigated further. The implications of using ...
5
Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... epidermal growth factor (EGF), fibroblast growth factor-β (FGF-β), heparin-like growth factor (HGF), keratinocyte growth factor (KGF), transforming ...
7
Transforming growth factor β and breast cancer: Transforming growth factor β/SMAD signaling defects and cancer
... that lead to expression of an AML1/Evi-1 fusion product under the control of the AML1 promoter [97]. The biological functions of Evi-1 are not well defined, but one way of contributing to a transformed ...
9
TGF-β1 and TGF-β2 abundance in liver diseases of mice and men
... - Transforming growth factor, TGF-βR-I, II, III - Transforming growth factor receptor type I, II and III, CM - collagen monolayer, CLD - chronic liver disease, Col1a1 – Collagen ...
20
Effects of Non-Collagenous Proteins, TGF-β1, and PDGF-BB on Viability and Proliferation of Dental Pulp Stem Cells
... of growth factors such as platelet-derived growth factor BB (PDGF-BB), transforming growth factor beta 1 (TGF-β1) and other bio-active molecules, sequestered during ...
9
Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells
... determined by radioreceptor binding inhibition assay and direct assessment of transforming growth factor biological activity correlated with Northern blot analysis. Although gradients in the ...
7
Original Article TGF β1 gene polymorphisms correlate with the susceptibility of osteoarthritis
... Abstract: Purpose: We investigated the potential role of transforming growth factor beta 1 (TGF β1) gene poly- morphisms (rs1800470 and rs1800469) in the occurrence of osteoarthritis (OA). ...
6
Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the ...
7
Transforming growth factor-beta receptor signalling is modulated by integrin-linked kinase
... keratinocyte growth medium (Ca 2+ -free EMEM supplemented with 8% Chelex resin- treated FBS, 100U/ml penicillin , 100μg/ml streptomycin, 74 ng/ml hydrocortisone, 5 μg/ml insulin, ...of 1 x 10 5 cells/cm 2 . ...
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