Transforming Growth Factor beta1
Original Article Transforming growth factor-beta1 promotes Geistlich Bio-Oss osteogenesis via inhibiting local inflammation response in vivo
... that transforming growth factor-beta1 (TGF-β1)-induced Treg cells inhibit the absorption of tissue-engineered cartilage caused by endogenous IFN-γ and ...
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Myofibroblasts and Transforming Growth Factor-Beta1 in Reactive Gingival Overgrowths
... and transforming growth factor-beta1 in fibrous and ossifying-fibrous epulis in an attempt to note their possible contribution in the formation of collagenous connective tissue of the ...
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Lens specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts
... cell growth (42), TGF- b can also stimulate corneal epithelial cell growth in the presence of NIH 3T3 cells or limbal fibroblasts, possibly by upregulation of ba- sic FGF, which could act on the corneal ...
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Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosis
... [9]. Transforming growth factor- b , a family of 25 kDa homodimeric multifunctional regulatory peptides, pos- sesses a number of biological functions, including extra- cellular matrix production and ...
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Transforming growth factor beta1 induces differentiation in human papillomavirus-positive keratinocytes.
... the lack of expression of morphologic or biochemical markers does not necessarily imply the irreversible loss of the ability to express that marker. This point illustrates the utility of the organotypic culture system ...
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Potential targets of transforming growth factor-beta1 during inhibition of oocyte maturation in zebrafish
... An interesting finding from this study is that TGF-β1 dif- ferentially regulates FSHR and LHR mRNA levels. We observed that basal FSH receptor mRNA levels were increased, while basal- and hCG-induced LH receptor mRNA ...
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Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells
... epithelial growth medium (BEGM) con- sisting of bronchial epithelial basal medium (BEBM, Lonza CC-3171, Walkersville, MD) and the BEGM SingleQuot Kit Supplements & Growth Factors (Lonza CC-4175) but ex- ...
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Transforming growth factor beta1/Smad signalling pathway of aortic disorders: histopathological and immunohistochemical studies
... terstitium may indicate a transformation from the endothelial cells to fibroblasts [14]. TbRI and type II receptor (TbRII) immunoreactivities were expressed more intensely in the dermatofibroma than in the normal dermal ...
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Evaluation of E-Cadherin and transforming growth factor beta1 in oral submucous fibrosis with and without malignant transformation
... In 2013 Xu 61 et al did a cross-sectional study in Chinese population to examine the role of TGFβ1 and hepatocyte growth factor in esophageal carcinogenesis and angiogenesis. The study groups were normal ...
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Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1
... The lung is comprised of multiple cell types including alveolar epithelial cells and macrophages in close vicin- ity, and cells communicate with each other, either in a paracrine manner through locally secreted ...
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Particle mediated gene transfer with transforming growth factor beta1 cDNAs enhances wound repair in rat skin
... for growth factor func- tion derives from the observation that supplementation or de- pletion of several cytokines can influence the rate of wound re- ...other growth factors as wound healing agents ...
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High glucose induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells
... vides two lines of evidence indicating that the hexosamine biosynthetic pathway is involved in the glucose-induced ex- pression and bioactivation of TGF- b 1 in mesangial cells; glu- cosamine mimicked the effects of high ...
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Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1
... BMAL1 is an essential component of the molecular feedback network. Inactivation of BMAL1 in mice re- sults in a complete loss of circadian rhythm under constant dark conditions [21]. BMAL1−/− mice is characterized by ...
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Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation
... Again proliferation of T cells was inhib- ited by TGFβ1-LAP loaded on TCR/CD28-activating beads (Figure 3B). Here however, TGFβ1-mediated sup- pression of T cell proliferation was less p[r] ...
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Different Risk Indictors of Diabetic Nephropathy in Transforming Growth Factor-beta1 T869C CC/CT Genotype and TT Geno¬type
... as transforming growth factor-β1 (TGF-β1) T869C (Leu 10 Pro) gene pol- ...ymorphism. Transforming growth factor-beta (TGF-β) is a multifunctional regulator that modu- lates cell ...
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Plasmid DNA encoding transforming growth factor beta1 suppresses chronic disease in a streptococcal cell wall induced arthritis model
... Transforming growth factor b is a potent immunomodula- tor with both pro- and antiinflammatory activities. Based on its immunosuppressive actions, exogenous TGF- b has been shown to inhibit ...
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Adenovector mediated gene transfer of active transforming growth factor beta1 induces prolonged severe fibrosis in rat lung
... respiratory tract directly. We have demonstrated that transient overexpression of active, but not latent, TGF-beta1 resulted in prolonged and severe interstitial and pleural fibrosis characterized by extensive ...
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1 Rap1 regulates hepatic stellate cell migration through
... gtpase rap1 regulates cell migration through regulation of small gtpase rhoa activity in response to 405. transforming growth factor-beta1[r] ...
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Idiopathic Pulmonary Fibrosis and Mutation of TGF-beta Gene, Codon 10
... JA. Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix ...
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Role of matrix metalloproteinase-9 in transforming growth factor-β1-induced epithelial–mesenchymal transition in esophageal squamous cell carcinoma
... cells. Transforming growth factor (TGF)-β1 is involved in the process of EMT in a variety of human ...various growth factors, including TGF-β1, in different cell ...
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