transforming growth factor β 1
Activation of the Connective Tissue Growth Factor (CTGF)-Transforming Growth Factor β 1 (TGF-β 1) Axis in Hepatitis C Virus-Expressing Hepatocytes
... HepG2 cells transfected with JFH-1 RNA over the first 36 hours of culture by Western blot (Fig. 6A & 6D) and RT-PCR (Fig. 6B). To assess whether this difference was reflected in downstream Figure 4. HCV ...
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miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity
... in transforming growth factor β 1 (TGF- β 1)-induced skin myofibroblasts compared with healthy skin or nontreated fibroblasts (p < ...TGF- β 1 stimulation ...
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Current progress in understanding the molecular pathogenesis of burn scar contracture
... secrete transforming growth factor- β 1 (TGF- β 1) and other cytokines, which can promote persistent myofibroblast activation via a positive regulation ...initiation ...
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Transforming growth factor β stimulates nerve growth factor production in osteoarthritic synovium
... TGF- β and NGF using immunohistochemistry, and analyzed the relationship between NGF and TGFB mRNA ...TGF- β (rhTGF- β ), rhTGF- β + ALK5 inhibitor SB505124, rhTGF- β + ...
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Tumour stromal interactions: Transforming growth factor β isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesis
... TGF- β in vivo, it is also important to appreciate that there are several extracellular controls on TGF-β function that can spatially and temporally regulate TGF- β action to allow context dependent ...
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Expression of epidermal growth factor, transforming growth factor-β1 and adiponectin in nipple aspirate fluid and plasma of pre and post-menopausal women
... epidermal growth factor (EGF), transforming growth factor-beta 1 (TGF- β 1), and adiponectin and evaluated menopausal status and body mass index (BMI) as potential ...
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Development of a two-step protocol for culture expansion of human annulus fibrosus cells with TGF-β1 and FGF-2
... with transforming growth factor (TGF- β 1) and fibroblast growth factor (FGF-2) culture for 14 days: group 1 had no GFs (control group); group 2 received TGF- ...
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Transforming growth factor beta and breast cancer: Tumor promoting effects of transforming growth factor β
... TGF- β -induced growth inhibitory responses and extracellular matrix responses may represent distinct processes in certain cell ...TGF-β1-mediated growth inhibition, but enhances the ability of TGF- ...
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Transforming growth factor β and breast cancer: Cell cycle arrest by transforming growth factor β and its disruption in cancer
... TGF- β -induced G 1 arrest occurs through induction of p15 and p21 genes, repres- sion of the c-myc, Cdc25A, cyclin E and cyclin A genes, and an increase in the association of p15, p21 and p27 with target ...
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Inflammatory biomarkers in type 2 diabetic patients: effect of glycemic control and impact of ldl subfraction phenotype
... Type 2 diabetes mellitus is one of the most common dis- eases in occidental society and it is associated with a high cardiovascular risk, not only due to the classical factors but also to a chronic low-grade inflammation ...
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Transforming growth factor β and breast cancer: Transforming growth factor β/SMAD signaling defects and cancer
... TGF- β signaling warrants closer investiga- tion of this ...TGF- β in breast cancer. A nuclear zinc-finger protein, Evi-1 is involved in leukemic transformation of hematopoietic cells subsequent to ...
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Transforming growth factor-β and abdominal aortic aneurysms
... Significant shortfalls exist in current AAA management strategies. In particular, the absence of effective drug therapies for AAA means that patients with early stage AAAs are managed conservatively requiring repeat ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients ...
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Transforming growth factor-β pathway activity in glioblastoma
... (Figure 1), suggesting that targeted approaches focusing on a particular isoform are unlikely to be successful in ...Figures 1 and 3). The strong correlation between TGF-β mRNA expression and the ...
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Transforming Growth Factor – β and Glioma
... Due to the increasing amount of evidence which suggest that the increase in TGF-β signaling is prominent in malignant tumors, the clinical application of TGF-β is being investigated further. The ...
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Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... epidermal growth factor (EGF), fibroblast growth factor-β (FGF-β), heparin-like growth factor (HGF), keratinocyte growth factor (KGF), ...
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Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough
... stored at -80°C before use. Frozen sections (6 m) were cut before fixed in cold acetone for 10 min. Sections were incubated in 10% normal horse serum to block non-spe- cific binding, followed by a mouse anti-human ...
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<p>Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes Combined Pluronic F127 Hydrogel Promote Chronic Diabetic Wound Healing and Complete Skin Regeneration</p>
... analyzed: 1) hUCMSC-exos group: 3 mL hUCMSC-exos; 2) hUCMSC supernatant group: 3 mL hUCMSC superna- tant; 3) PF-127 hydrogel group: 1 mL 24% PF-127 with DMEM (Gibco, USA); and 4) Control group: 1 mL ...
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The Role of p62/SQSTM1 in TGFβ-dependent EMT and Autophagy
... Transforming growth factor beta (TGFβ) is a cytokine that regulates cellular adhesion, proliferation and ...sequestosome 1 (p62/SQSTM1) ...
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Transforming Growth Factor Β in Psoriasis: Pathogenesis and Therapy
... prominent alterations in dermal capillary vasculature~and the presence of dermal and epidermal T cells, monocytehacrophages, and polymorphonuclear leukocytes?.6 We have recently shown th[r] ...
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