Transforming growth factor β1
Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-β1
... The plasticity of differentiated adult cells could have a great therapeutic potential, but at the same time, it is characteristic of progression of serious pathological states such as cancer and fibrosis. In this study, ...
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Original Article Association of transforming growth factor-β1 gene polymorphisms in pneumoconiosis susceptibility: a meta-analysis
... Several articles have identified the role of transforming growth factor-β1 (TGF-β1) polymorphisms in development of pneumoconiosis, however, the results remain inconclusive. The ...
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ASSOCIATION BETWEEN TRANSFORMING GROWTH FACTOR-β1 AND INTERLEUKIN-4 AND CHILDHOOD ASTHMA IN ZAGAZIG UNIVERSITY HOSPITALS
... Background: Interleukin (IL) 4 and transforming growth factor β1 (TGF-β1) are two key cytokines involved in a Th2-type inflammation characteristic of asthma. This type has more ...
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The effect of transforming growth factor-β1 on nasopharyngeal carcinoma cells: insensitive to cell growth but functional to TGF-β/Smad pathway
... and growth fac- tors in NPC, where most of these investigations have attempted to understand the roles played by cytokines and growth factors during development and chemopre- vention in ...of ...
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TRANSFORMING GROWTH FACTOR-Β1 T869C (CODON 10) GENE POLYMORPHISM IN TYPE 2 DIABETES IRAQI PATIENTS
... causative factor to develop DM is ...mortality. Transforming growth factor-β1 (TGF-β1), a pleiotropic cytokine, is a key player in immune regulation and plays an important role ...
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The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition
... vessel growth, also known as angiogenesis, is essential during organ development and tissue repair for the supply of nutrients and oxygen to organs and ...of growth factors, such as vascular endothelial ...
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Reciprocal balance of hepatocyte growth factor and transforming growth factor-β1 in renal fibrosis in mice
... Mizuno et al: HGF as an intrinsic repair factor in fibrosis 942 Fig. 3. Influence of neutralizing treatment with an anti-HGF antibody ( ␣-HGF) on renal function and morphology in nephrotic ICGN mice. (A) Changes ...
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Reciprocal functions of hepatocyte growth factor and transforming growth factor-β1 in the progression of renal diseases: A role for CD44?
... Transforming growth factor- 1 has been shown to in- duce epithelial-mesenchymal transition in vitro [24], which can be blocked by ...Hepatocyte growth factor exerts this in vivo ...
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Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1
... 15]. However, the precise mechanisms via which pirfeni- done suppresses lung fibrosis are still unclear. In this study, we evaluated the effects pirfenidone on TGF-β1-mediated contraction of ECM and migration of ...
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The Effect of Curcumin on Regression of Liver Fibrosis through Decreased Expression of Transforming Growth Factor-β1 (TGF-β1)
... Immunohistochemistry The analysis of TGF-β1 expression in liver tissue was measured by immunohistochemical kits Anti TGF-β1 (No. BS series 0086R, Elabscience, Singapore, Singapore) and Secondary Antibodies ...
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Induction by transforming growth factor β1 of epithelial to mesenchymal transition is a rare event in vitro
... were growth inhibited by TGF-β1, many of the cancer cell lines were insensitive to the growth inhibitory effects of ...TGF-β1-mediated growth inhibition was accompanied by an increase ...
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Transforming Growth Factor β1 Receptor II Is Downregulated by E1A in Adenovirus-Infected Cells
... A key question is whether the adenovirus-mediated down- regulation of TRII and TGF-1 signaling that we had ob- served in cultured cells is physiologically relevant. Unfortu- nately, there is not an established animal ...
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Effects of enamel matrix derivative and transforming growth factor-β1 on human osteoblastic cells
... Although the roles of ALP during the process of matrix mineralization are still not fully clarified, it has been pro- posed that such enzyme generates the phosphate needed for hydroxyapatite formation. In addition, ALP ...
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Increased expression of collagens, transforming growth factor β1, and β3 in gluteal muscle contracture
... of cultured fibroblasts might have been by chance those inactive in other stages, as supported by the work of Zhang [21]. TGF-bs are pluripotent growth factors and are highly conserved between species. There is ...
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Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1
... In this study, we have demonstrated that TGF-β potently induces insensitivity to glucocorticoid transactivation in epithelial cells, without impacting on glucocorticoid trans- repression. Demonstration of the interaction ...
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Study of gonadic growth factors: Seminal transforming growth factor β1, epidermal growth factor and insulin like growth factor I and their relationship with male infertility
... The growth factor being primarily peptides, and their manipulation identification in a com- plex environment such as seminal plasma, however, re- quires a lot of precautions if you do not want to expose ...
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Rapamycin Inhibits Transforming Growth Factor β1 Induced Fibrogenesis in Primary Human Lung Fibroblasts
... Rapamycin inhibited the mTOR/p70S6K pathway in a dose- dependent manner. However, the effect on collagen type III and fibronectin secretion did not occur in a dose-dependent manner, and the reason remains unclear. At ...
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Density and Duration of Pneumococcal Carriage Is Maintained by Transforming Growth Factor β1 and T Regulatory Cells
... Measurements and Main Results: We describe the previously unknown immunological basis of noninvasive carriage and highlight mechanisms whose perturbation may lead to invasive disease. We identify the induction of active ...
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Original Article Effect of transforming growth factor-β1 869C/T polymorphism and radiation pneumonitis
... Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumo- nitis in patients with non-small-cell lung cancer. treated wit[r] ...
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Platelet-derived transforming growth factor-β1 promotes keratinocyte proliferation in cutaneous wound healing.
... TGF β1 did not exhibit enhanced collagen deposition or proliferation, suggesting that platelet-derived TGF β1 is not a key promoter of these wound healing ...TGF β1-driven proliferation in response ...
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