Transient receptor potential channels
Original Article Changes of stretch-activated channel-transient receptor potential channels in atrial myocardium of rabbits with heart failure
... Abstract: Transient receptor potential channels (TRPC) are shown recently to play an important role in the develop- ment of heart failure and ...of transient receptor ...
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Original Article Role of transient receptor potential channels in airway smooth muscle cell growth
... Abstract: The proliferation of airway smooth muscle cells (ASMCs) plays a vital role in airway remodeling. Besides, transient receptor potential channels (TRPC) play a key role in pathological ...
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Polymodal roles of transient receptor potential channels in the control of ocular function
... Subsequent to the breaching of the corneal epithelial base- ment membrane by a severe injury, transforming growth factor–β (TGFβ) infiltrates into the stroma and activates its cognate receptor on human fibroblasts ...
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How does rhinovirus cause the common cold cough?
... NOD-like receptor X-1 ultimately producing reactive oxygen ...of receptor expression, such as transient receptor potential channels which have a prolific effect to cause cough ...
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Homer, TRP channels and calcium : the signalling triad of growth cone motility
... The regulation of growth cone motility by BDNF is calciumdependent Song etal., 1997 and recent experiments have confirmed that transient receptor potential channels TRPC contribute to BD[r] ...
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Role of the transient receptor potential vanilloid 1 in inflammation and sepsis
... voltage-gated channels, TRPV1 and other transient receptor potential channels lack an array of charged residues in their transmembrane segment ...
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Stenger, Bernhard (2018): Transient receptor potential A1 channels and their role in the cytotoxicity of sulfur mustard. Dissertation, LMU München: Medizinische Fakultät
... Der chemische Kampfstoff Schwefel-Lost (S-Lost) weist einen stechenden, senf- oder knoblauchartigen Geruch auf, was zum Synonym „Senfgas“ führte. Das Wahrnehmen von Gerüchen ist Teil der physiologischen Chemosensorik - ...
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Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... Transient receptor potential vanilloid-1 (TRPV1) is a member of the TRP family of channels that are responsible for nociceptive, thermal and mechanical ...
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Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... TRPV1 channels are activated by a variety of other plant-derived vanilloids including, camphor and resiniferatoxin (RTX), and putative endogenous vanilloids such as the endocannabinoid, anandamide, some ...
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Transient receptor potential (TRP) gene superfamily encoding cation channels
... Transient receptor potential (TRP) non-selective cation channels constitute a superfamily, which contains 28 different ...TRP channels in different ocular ...
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Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression
... TRPML channels are 6 transmembrane-spanning proteins that consist of cytosolic N- and C-termini, and a pore-loop domain between S5 and ...TRPML-2 channels localize in endosomal and lysosomal compartments ...
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Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture responding channel”
... mechanosensitive channels are involved in the reception of ...The transient receptor potential vanilloid receptors 1 and 4 (TRPV1 and TRPV4) and the acid-sensing ion channel 3 (ASIC3) are ...
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Transient Receptor Potential Ion Channels in the Etiology and Pathomechanism of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
... TRP channels cause depola- rization and hence activation of voltage-dependent ion channels, thus permitting changes in intracellular Ca 2+ concentration ...
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Transient Receptor Potential-Like Channels Are Essential for Calcium Signaling and Fluid Transport in a Drosophila Epithelium
... Calcium signaling is an important mediator of neuropeptide-stimulated fluid transport by Drosophila Malpighian (renal) tubules. We demonstrate the first epithelial role, in vivo, for members of the TRP family of calcium ...
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Abstract: ThermoTRP channels (thermoTRPs) define a subfamily of the transient receptor
... ThermoTRP channels (thermoTRPs) define a subfamily of the transient receptor potential (TRP) channels that are activated by changes in the environmental temperature, from noxious cold ...
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Ocular transient receptor potential channel function in health and disease
... Worldwide, the number of people needing relief from ocular dysfunction is on the rise. One of the reasons for this increase is a change in lifestyle due to reliance on video display terminals and stresses imposed by ...
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Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy
... these cells. We propose that TRPC6 is the major TRPC channel expressed in MCF-7 cells. However correlation of the permeation and pharmacological profiles of the cati- onic current in MCF-7 cells as described by El Hiani ...
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A Novel Mechanism for Calmodulin Dependent Inactivation of Transient Receptor Potential Vanilloid 6
... If the formation of the 1:2 complex has a functional role, the increased affinity of the second binding event resulting from the L707A mutation would be expected to stabilise the inactivated state and thus increase the ...
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THE ROLE OF TRANSIENT RECEPTOR POTENTIAL VANILLOID 1 RECEPTOR IN DESIPRAMINE INDUCED ANALGESIC EFFECT IN DIABETIC MICE
... INTRODUCTION: Antidepressants are widely used in chronic pain states including both inflammatory and neuropathic pain conditions. It has been suggested that antidepressant drugs have specific analgesic properties, and ...
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<p>Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling</p>
... angiotensin receptor antagonist valsartan, which has crucial roles in protecting podocytes, was used as a positive ...TRPC6 channels is reduced) and Y-27632 (inhibitor of ROCK, a downstream effector of ...
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