Translational control
Translational control of cyclins
... Translational control of cyclin E1 by DDX3 in mammals Mammalian DDX3, as its yeast Ded1 homolog, has been implicated in translational control ...cause translational inhibition during ...
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Translational Control in Plasmodium and Toxoplasma Parasites
... precise control of gene expression at all levels, including ...regulate translational control in Plasmodium and Toxoplasma, with a particular emphasis on the phosphorylation of the ␣ subunit of ...
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Temporal complexity within a translational control element in the nanos mRNA
... spatial control of gene expression during development in a variety of organisms (Wickens et ...of translational control to subcellular mRNA localization facilitates targeting and restriction of ...
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Key contribution of eIF4H-mediated translational control in tumor promotion
... in translational control and can promote cellular transformation by preferentially regulating the translation of potent growth and survival factor mRNAs, indicating that eIF4H is a promising new molecular ...
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Translational control of the heat shock response in Xenopus oocytes
... The results described illustrate the difficulties encountered in using SP6 RNAs to study translational control in vivo. Firstly, it is impossible to synthesize RNA in vitro which is identical to endogenous ...
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Loss of translational control in yeast compromised for the major mRNA decay pathway
... Translational control via eIF2␣ kinases is an evolutionarily conserved response to ...major control point of protein synthesis (reviewed in reference ...divergent translational stresses that ...
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Translational control mechanisms in the p53 response network
... post-transcriptional control can modulate classical p53-regulated ...and translational levels, quantitative differences between the transcriptome, subpolysomal and polysomal RNAs were ...the ...
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Translational Control of the SigR Directed Oxidative Stress Response in Streptomyces via IF3 Mediated Repression of a Noncanonical GTC Start Codon
... of translational control of the sigma factor SigR and its cognate antisigma factor RsrA that may have broader implications for understanding the expression of other sigma-antisigma ...This ...
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NAT1/DAP5/p97 and Atypical Translational Control in the Drosophila Circadian Oscillator
... address translational control genes, we used 70 UAS-RNAi constructs targeting 34 genes impacting transla- tion and RNA metabolism in combination with the pdf-GAL4 driver (pdf ...the control lines ...
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Post-Translational Control of Alcohol Dehydrogenase Levels in Drosophila melanogaster
... Natural populations of Drosophila melanogaster have been shown to contain high degrees of regulatory gene variation for a num- ber of enzyme loci including alcohol dehydrogenas[r] ...
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Association of Maternal mRNA and Phosphorylated EIF4EBP1 Variants With the Spindle in Mouse Oocytes: Localized Translational Control Supporting Female Meiosis in Mammals
... key translational regulator, EIF4EBP1, undergoes a dynamic and complex spatially regulated pattern of phosphorylation at sites that regulate its association with EIF4E and its ability to repress ...EIF4EBP1 ...
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Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila
... To my knowledge this is the first proposal that mitochondrial genes contain IRESs. The majority of cellular IRES genes have been implicated in stress response. A lot of these have focused on upregulation under hypoxia, ...
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Stress Granules and P Bodies: An Insight into mRNA Translational Control and Decay
... In mammals, Smaug 1 (SMG) is described as an RNA-binding translational regulator involved in mRNA silencing and deadenylation (Baez and Boccaccio, 2005). SMG regulates the expression of target mRNAs by at least ...
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Translational control of protein synthesis after infection by vesicular stomatitis virus.
... Infection does result in a reduction in the rate of initiation of translation of all predominant species of cellular mRNA, but translation of cellular and viral mRNA's which encode for t[r] ...
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Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila
... One common downstream component of both the ILSP and the TOR pathways is the translational repressor 4EBP. Decreased ILSP signaling transcriptionally upregulates 4EBP via the forkhead transcription factor FOXO ...
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AKH BIOSYNTHESIS: TRANSCRIPTIONAL AND TRANSLATIONAL CONTROL OF TWO CO LOCALISED PROHORMONES
... In the present paper, we describe an mRNA encoding preproAKH II and show that it corresponds to the second major product of in vitro translation and that it codes for only one copy of an AKH prohormone (proAKH II). This ...
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Translational control of cytomegalovirus gene expression is mediated by upstream AUG codons.
... To understand how the cis-acting signal previously mapped within the 5' leader of the major P gene transcript exerted its effect on gene expression, we first determined the cellular loca[r] ...
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Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer
... Cancer is a leading cause of death worldwide. Aberrant promoter hypermethylation of CpG islands associated with tumor suppressor genes can lead to transcriptional silencing and result in tumorigenesis. DNA ...
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TRANSCRIPTIONAL AND TRANSLATIONAL CONTROL OF ZEBRAFISH MESODERMAL DEVELOPMENT
... There are several instances where the rules for decoding mRNA are altered. While rare, this occurs at specific sites, where signals or structures are present in the mRNA sequence. The specific pausing of ribosomes at ...
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Post-Translational Control of Retinoblastoma Protein Phosphorylation
... The retinoblastoma protein has been extensively studied in regards to post-translational modification primarily through phosphorylation by CDKs. More recent work has begun to emerge in the field that has begun to ...
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