Treponema pallidum
Prevalence of hepatitis B virus, hepatitis C virus, human immunodeficiency virus and Treponema pallidum infections in hospitalized patients before transfusion in Xiangya hospital Central South University, China from 2011 to 2016
... Blood transfusion, especially component transfusion such as packed red blood cells, platelet concentrates, fresh frozen plasma, individual factor concentrates, and cryoprecipitate, has become an indispensable medical ...
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Long Term In Vitro Culture of the Syphilis Spirochete Treponema pallidum subsp pallidum
... of Treponema pallidum subsp. pallidum, the spirochete that causes syphilis, has been hindered by an inability to culture the organism con- tinuously in vitro despite more than a century of ...T. ...
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Molecular docking studies of bioactive compounds from the leaves of Epiphyllum oxypetalum against Treponema pallidum, Zika virus and liver cirrhosis
... The Epiphyllum oxypetalum is a unique plant that belongs to a cactaceae family. Traditionally, this plant mainly cures sexually transmitted diseases, liver infection, and antiviral disease. The molecular docking analysis ...
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Clinical Value of Treponema pallidum Real Time PCR for Diagnosis of Syphilis
... T. pallidum PCR results that we found in our ...T. pallidum real-time PCR negative, had a suspected case of secondary or latent syphilis or had a serology result that corresponded with previous syphilis ...
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Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin Trafficking Protein
... spirochete Treponema pallidum is an important human pathogen but a highly enigmatic bacterium that cannot be cultivated in ...T. pallidum lacks many biosynthetic pathways and therefore has evolved ...
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Treponema pallidum Immunohistochemistry is positive in human intestinal Spirochetosis
... The Treponema pallidum immu- nostain has been shown to be positive in cases of intes- tinal spirochetosis in a prior study [8] but this was not the main focus of that ...
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Detection of the A2058G and A2059G 23S rRNA Gene Point Mutations Associated with Azithromycin Resistance in Treponema pallidum by Use of a TaqMan Real Time Multiplex PCR Assay
... in Treponema pallidum ...T. pallidum that were obtained from an azithromycin resistance surveillance study conducted in the United States were ...T. pallidum strains were ...T. pallidum ...
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Detection of Treponema pallidum by a sensitive reverse transcriptase PCR
... Syphilis is diagnosed by serologic testing or by identification of the causative agent, Treponema pallidum. The bacterium has historically been detected in clinical specimens by dark-field microscopy, ...
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Sensitivity and specificity of monoclonal antibodies directed against antigenic determinants of Treponema pallidum Nichols in the diagnosis of syphilis
... Murine anti-Treponema pallidum monoclonal antibodies were employed in studies on sensitivity and specificity of binding to examine their potential for use in the detection of low numbers[r] ...
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Cerebrospinal Fluid Treponema pallidum Particle Agglutination Assay for Neurosyphilis Diagnosis
... CSF Treponema pallidum particle agglutination assay (CSF-TPPA) for neurosyphilis diagnosis suggest that, like CSF-FTA-ABS, it may be diagnostically sensitive (4, ...The Treponema pallidum ...
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Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis
... T. pallidum. Treponema pallidum subsp. pallidum (Nichols strain), originally purchased from the Statens Serum Institut, Copenhagen, Denmark, was maintained in adult male New Zealand White ...
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Borrelia burgdorferi and Treponema pallidum: a comparison of functional genomics, environmental adaptations, and pathogenic mechanisms
... and Treponema pallidum subspecies pallidum, the agent of venereal ...T. pallidum must be grown in the testicles of live rabbits to obtain bacte- ria for experimental use ...
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Evaluation of the Recombinant Protein TpF1 of Treponema pallidum for Serodiagnosis of Syphilis
... by Treponema pallidum subsp. pallidum, and diagnosis with sensitive and specific meth- ods is a challenging process that is important for its prevention and ...T. pallidum Nichols strain and ...
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Sequence Variation of Rare Outer Membrane Protein β Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp pallidum, the Syphilis Spirochete
... spirochete Treponema pallidum subsp. pallidum, has undergone a dramatic resurgence in the United States, particularly among men who have sex with men ...T. pallidum subsp. pallidum ...
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Evaluation of a Treponema pallidum enzyme immunoassay as a screening test for syphilis.
... In our study, 15 samples were nonreactive in the RPR test, yielded positive or equivocal CAPTIA Syphilis-G results, and were reactive or minimally reactive in the FTA-ABS test.. Upon rep[r] ...
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Evaluation of the microenzyme linked immunosorbent assay with Treponema pallidum antigen
... Treponemra pallidum, Nichols strain, was evaluated in the ELISA procedure, and the results were compared with those obtained with the Venereal Disease Research Laboratory VDRL test 6, th[r] ...
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Evaluation of a PCR Test for Detection of Treponema pallidum in Swabs and Blood
... lesions. The retention of patients with uncertain DFM results in the study decreased the specificity to 88% due to the possible pres- ence of nontreponemal spirochetes in mucosal samples from oral sites. Indeed, T. ...
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Complete genome sequence of Treponema pallidum strain DAL-1
... Each DAL-1 region not sequenced by Illumina and con- taining differences from the Nichols genome was resequenced using the Sanger method.. In addition, all other discrepancies between[r] ...
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Specific immunofluorescence staining of Treponema pallidum in smears and tissues
... pallidum in chancre smears 15 can easily be stained with specific fluorescein-labeled anti- T.pallidum conjugate absorbed with Treponema phagedenis.. However, this conjugate has not been[r] ...
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Sensitive detection of Treponema pallidum by using the polymerase chain reaction
... Positive PCR results were obtained from serum, CSF, and amniotic fluids of untreated syphilis patients but not from control specimens.. Representative results are shown in Fig.[r] ...
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