TRIAZOLE RING
Synthesis and Anti-Inflammatory Activity of Hydrazide-Hydrazones Bearing Anacardic Acid and 1,2,3-Triazole Ring Based Hybrids
... phenyl ring flanked between hydrazone group and the triazole ring, while the protons resonating at ...phenyl ring and anacardic acid ring ...
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Use of triazole ring formation to attach a Ru/TsDPEN complex for asymmetric transfer hydrogenation to a soluble polymer
... Dichloromethane 200 cm3 and water 100 cm3 were then added to the reaction mixture and the organic layer separated, re-extracted with water 4 x 100 cm3 and saturated NaCl solution 100 cm3[r] ...
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Crystal structures of 2,6 bis[(1H 1,2,4 triazol 1 yl)methyl]pyridine and 1,1 [pyridine 2,6 diylbis(methylene)]bis(4 methyl 1H 1,2,4 triazol 4 ium) iodide triiodide
... the triazole ring and the nitrogen lone pairs of the neighboring triazole molecule (Table ...the triazole ring (C1— H1 N7 and C11—H11 N7), and b) the nitrogen atom is in the second ...
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1 [(1 Benzyl 1H 1,2,3 triazol 4 yl)methyl]indoline 2,3 dione
... a triazole ring which is connected to a benzyl ring as shown in ...indoline ring and the two carbonyl oxygen atoms are nearly coplanar, with the largest deviation from the mean plane being ...
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5 [(1H 1,2,4 Yriazol 1 yl)methyl] 4 (4 fluorobenzylideneamino) 2H 1,2,4 triazole 3(4H) thione
... Compounds containing the 1,2,4-triazole ring possess a broad pharmacological activity spectrum encompassing anti-inflam- matory (Prasad et al., 1989), sedative, smooth-muscle relaxa- tion (Gall et al., ...
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Crystal structure, computational study and Hirshfeld surface analysis of ethyl (2S,3R) 3 (3 amino 1H 1,2,4 triazol 1 yl) 2 hydroxy 3 phenylpropanoate
... The triazole ring system has attracted considerable interest among synthetic organic chemists and those dealing with medicinal compounds because of its versatile potential to interact with biological ...
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Synthesis, Characterization and Thermal Behavior Study of New 1,2,3-Triazole Derivatives Containing 1,3,4-Oxadiazole Ring
... 1,2,3-triazole ring system with 1,3,4-oxadiazole ring system in one molecule to obtain new heterocyclic compounds such as 11-15 as described in Scheme ...
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← Return to Article Details ZIDOVUDINE: STRUCTURAL MODIFICATIONS AND THEIR IMPACT ON BIOLOGICAL ACTIVITIES AND PHARMACOKINETIC PROPERTIES
... Azido group has been converted into triazole ring and resultant compounds exhibited anticancer activities in addition to antiviral activities. Lewandowski et al. covalently conjugated AZT derivatives to ...
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1 [2 (4 Bromobenzyloxy) 2 phenylethyl] 1H 1,2,4 triazole
... planar triazole ring is oriented with respect to the phenyl and bromobenzene rings at dihedral angles of ...the ring planes of the corresponding triazole, phenyl and bromobenzene, ...
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Comprehensive spectral identification of key intermediates to the final product of the chiral pool synthesis of radezolid
... This conclusion is also confirmed by the occurring in this spectrum the peak correlation at 7.86 ppm/52.1 ppm between the proton signal assigned to triazole ring (CH group) and a ca[r] ...
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Crystal structure of catena poly[[(N,N diethyl 3 mesitylsulfonyl 1H 1,2,4 triazole 1 carboxamide κN1)silver(I)] μ nitrato κ3O,O′:O]
... cafenstrole ligand molecule, one Ag I atom and one nitrate ion. The Ag I atom, with a distorted trigonal–pyramidal environment, is coordinated by one nitrogen atom of a triazole ring, two oxygen atoms of a ...
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4 Amino 3,5 bis(4 pyridyl) 1,2,4 triazole
... A perspective view of (I), including the atomic numbering scheme, is shown in Fig. 1. In the structure of (I), the two pyridine rings make dihedral angles of 35.7 (2) and 16.8 (2)° with the mean plane of the central ...
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Synthesis, Characterization and Thermal Stability Study of New Heterocyclic Compounds Containing 1,2,3-Triazole and 1,3,4-Thiadiazole Rings
... of the DTG curve helps to permit the direct application of the rate function of the change in the weight of the target sample to the study of phenomena occurring during thermogravimetric analysis. Practically, depending ...
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3 Benzyl 4 (p fluorobenzylidenamino) 4,5 dihydro 1H 1,2,4 triazol 5 one
... The bonds and angles in (I) (Table 1) are consistent with those in similar substituted triazoles (Kahveci et al., 2003; CËoruh et al., 2003; IsËõk et al., 2003). The benzyl rings and 1,2,4- triazole ring ...
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Sythesis and biological evolution of trizole derivatives
... membered triazole ring exists in two tautomeric forms i.e. 1, 2, 3-triazole and 1, 2, ...4- triazole and 4H-1, 2, 4-triazole collectively known as s-triazoles The s-triazole ...
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Synthesis, Characterization and Anticonvulsant Activity of Some Novel 4, 5-Disubstituted-1, 2, 4-Triazole Derivatives
... the triazole ring is an important lead moiety in the field of agriculture, microbiology and medicine which exhibits a broad spectrum of biological activities such as anticancer (Li et ...
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4′ Phenyl 3,4 dihydro 2H spiro[naphthalene 1,3′ [1,2,4]triazole] 5′ thione
... In the title compound, the phenyl group (C3–C8) attached to N3 makes a dihedral angle of 57.29 (11)° with the mean plane of the triazole ring (N1–N3/C1/C2) which in turn makes an angle of 86.83 (12)° with ...
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Design, synthesis, and antifungal activities of novel triazole derivatives containing the benzyl group
... on the structure–activity relationships (SAR) of antifungal azoles were undertaken, and these studies led to new com- pounds endowed with better biological and pharmacological properties. These studies indicated that the ...
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1 Acetyl 3 (p chlorobenzyl) 4 (p chlorobenzylidenamino) 4,5 dihydro 1H 1,2,4 triazol 5 one
... 1,2,4-triazole ring systems are very interesting because of their similarity to the 1,3-imidazole bridging found in the copper–zinc protein superoxide dismutase (Feiters, 1990) and for their ability to act ...
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N [4 Ferrocenyl 5 (1H 1,2,4 triazol 1 yl) 1,3 thiazol 2 yl] 2 nitrobenzamide
... thiazole ring (P1), the 2-nitrophenyl ring, C17–C22 (P2), the triazole ring (P3), the substituted cyclopentadienyl ring, C4–C8 (P4), and the cyclopentadienyl ring, C9–C13 ...
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