Trichuris muris
Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a / mice
... parasite Trichuris muris ( T. muris ) and Mdr1a-/- mice, a genetic model of inflammatory bowel disease linked to deficiency of a key transporter protein in the gut ...T. muris induces severe ...
12
In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris
... intestine, Trichuris muris, and confirm that the cysteine pro- teinases present in the plant extracts are the active ...T. muris, demonstrating that enzyme activity survived passage to the caecum and ...
10
Bacteria induced egg hatching differs for Trichuris muris and Trichuris suis
... Trichuris muris and T. suis, whipworms of mice and pigs, respectively, invade the mucosa of the large intes- tine [1 – 3]. The life cycle is direct with embryonated eggs (each containing a fully developed ...
7
An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro
... of Trichuris muris, the laboratory model parasite for human trichuriasis, by investigating the actions of an RXR-active compound on ...T. muris viability. T. muris is maintained in laboratory ...
9
Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection
... the gut, such as with the gut-dwelling nematode parasite Trichuris muris. Gc treatment impairs these Th2 responses and permits the parasitic worms to evade expulsion from the gut. The allergic response ...
13
Characterization of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host–parasite communication
... whipworm Trichuris muris has been extensively used as a model to study human whipworm ...T. muris . We identify 148 proteins secreted by T. muris and show for the first time that the mouse ...
16
Effect of combinations of marketed human anthelmintic drugs against Trichuris muris in vitro and in vivo
... Clinical trials have been conducted with the four syn- ergistic combinations reported here (Figure 1). Ironically these trials have been conducted without any preclinical supporting information, either on efficacy or ...
7
Development of an in vitro drug sensitivity assay for Trichuris muris first stage larvae
... The assay methodology was adapted from the assays described for hookworm and Strongyloides spp. [21] and for adult T. muris [10-12]. Mebendazole, levamisole, iver- mectin, nitazoxanide and oxantel pamoate were ...
8
Compounds derived from the Bhutanese daisy, Ajania nubigena, demonstrate dual anthelmintic activity against Schistosoma mansoni and Trichuris muris
... Luteolin (3), with a LogP value of 2.6, meets the Lipinski rule of 5 criterion for drug-likeness [46]. Generally, compounds with LogP values in the range of 2–3 are more likely to diffuse/per- meate through the cell ...
18
Mucosal immune responses following intestinal nematode infection
... epithelium. Trichuris muris larvae live embedded within IEC within the caecum (55), and increased epithelial cell proliferation and turnover can result in parasite ...T. muris infection is con- ...
14
Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis
... Interestingly, TSLP was shown to be important for protective immunity following infection with the gastrointestinal nematode Trichuris muris by limiting Th1- and Th17-induced mucosal dam[r] ...
9
Prevalence and risk factors of Ascaris lumbricoides (Linnaeus, 1758), Trichuris trichiura (Linnaeus, 1771) and HBV infections in Southwestern China: a community based cross sectional study
... We found that HBV infection was associated with fertilization pattern and farm work activities. Fertilization with faeces after disposal (i.e. faeces processed with fer- mentation, drying and other hazard-free ...
11
Genetic characterisation and phylogenetic status of whipworms (Trichuris spp ) from captive non human primates in China, determined by nuclear and mitochondrial sequencing
... ciated Trichuris whipworms in Chinese zoos, a number of questions are apparent: (i) what are the potential routes of parasite introduction and establishment (nat- ural or cross infections); (ii) what is the most ...
16
Epidemiological and clinical correlates of malaria helminth co infections in southern Ethiopia
... Soil-transmitted helminths (STH), on the other hand, are a group of common parasites that infect more than a billion people worldwide [5]. In Ethiopia, like other devel- oping countries, infections with the major STH, ...
7
Prevalence and Intensity of Gastro-Intestinal Helminthiasis Among School Age Children in Nkondjock, Littoral-Cameroon
... Abstract: Gastro-intestinal helminthiasis is an infection which affects at least one person in two in the world and mainly school age children. Our study was conducted with the objective of determining the prevalence and ...
5
Parasite load of European brown hares in Austria and the Czech Republic
... binocular microscope. The number of T. retortae- formis nematodes isolated was then recalculated for the total volume. Scoleces and tapeworm segments were also isolated from the intestinal contents. The contents of the ...
8
Evaluating Effect of Albendazole on Trichuris trichiura Infection: A Systematic Review Article
... In the present study, the estimated RR was 1.99 with 95% confidence intervals of 1.71 to 2.31, indicating that the cure ratio of individu- als infected with Trichuris trichiura using alben- dazole was almost two ...
7
Antigenic Cross-reactivity among Haemonchus contortus, Oesophagostomum columbianum and Trichuris ovis of Goat
... mall ruminant livestock are the frequent victim of mixed nematode infection throughout the world including India. Haemonchus contortus, Oesophagostomum columbia- num and Trichuris ovis are the most common ...
7
Effect of bryostatin-1 as an anthelmintic drug on adult Syphacia muris infection in rats
... Syphacia muris worms recovered from infected bryostatin-1-untreated rats are small worms and clear white when alive which possess a narrow pointed poster- ior ...
8
Efficacy and reinfection with soil transmitted helminths 18 weeks post treatment with albendazole ivermectin, albendazole mebendazole, albendazole oxantel pamoate and mebendazole
... The most common soil-transmitted helminths (STH; As- caris lumbricoides , hookworms and Trichuris trichiura ) infect approximately 1.5 billion people [1] worldwide with the highest prevalences in Asia and Africa. ...
10