Triple Negative Breast Cancer
Top PDF Triple Negative Breast Cancer:
Triple-negative breast cancer: treatment challenges and solutions
... BC, breast cancer; BL, basal-like; CSC, cancer stem cells; DNA, deoxyribonucleic acid; EGFR, epidermal growth factor receptor; EMT, epithelial- mesenchymal-transition; iGF-1R, insulin-like growth ...
15
RNF181 modulates Hippo signaling and triple negative breast cancer progression
... Background: Breast cancer ranks No. 1 in women cancer incidence, while triple negative breast cancer (TNBC) is the most aggressive and the worst prognostic subtype in all ...
11
Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer
... promoting cancer cell survival as well as tumorigen- esisis is well documented ...BRCA1-mutated triple-negative breast cancer ...
15
Clinicopathological Characteristics of Basal Type Breast Cancer in Triple Negative Breast Cancer
... ventional chemotherapy is currently used in clinical prac- tice and it effectiveness is limited [1]. Moreover, TNBC consist of two subtypes; basal and nonbasal type. The terms TNBC and basal type often are used inter- ...
5
Novel therapeutic strategies for patients with triple-negative breast cancer
... Abstract: Triple-negative breast cancer (TNBC) represents a very heterogeneous group of breast diseases. Currently, the backbone of therapy for TNBC is mainly chemotherapy as there are ...
10
Roles of eIF3m in the tumorigenesis of triple negative breast cancer
... Background: Without targets, triple negative breast cancer (TNBC) has the worst prognosis in all subtypes of breast cancer (BC). Recently, eukaryotic translation initiation ...
16
Radiological diagnostics of triple negative breast cancer: a review
... of breast MR imaging associated with TRN breast ...detecting triple negative breast ...cally triple negative breast ...this cancer. However, breast MR ...
9
Triple-negative breast cancer: new perspectives for targeted therapies
... Abstract: Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical ...five breast cancer subgroups: ...
17
Osthole inhibits triple negative breast cancer cells by suppressing STAT3
... Triple-negative breast cancer (TNBC) is a unique subset of human breast cancer that is characterized by negative estrogen receptor (ER), progesterone receptor (PR) and ...
11
Immunotherapeutic interventions of Triple Negative Breast Cancer
... with cancer progression and thus serve as potential immunotherapeutic targets ...that breast cancer (BC) is a non-immunogenic disease with fewer immunogenic tumour antigens [10], so BC has not been ...
19
Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer
... and triple-negative breast cancer (TNBC) has the highest propensity to develop distant metastases when there is evidence of central ...by cancer-associated fibroblasts (CAFs) promote ...
13
Comparative antiproliferative effects of iniparib and olaparib on a panel of triple negative and non triple negative breast cancer cell lines
... in triple-negative breast cancer should not be abandoned at this point in time because of the negative phase III trial results with ...
9
Identification of candidate genes associated with triple negative breast cancer
... CCLE: Cancer Cell Line Encyclopedia; CD68: macrophage antigen; CD8: T cell antigen; CEL: cell intensity file; DHCR24: 24-dehydrocholesterol reductase; DMEM: Dulbecco’s Modified Eagle Minimum essential media; ESR1: ...
14
Approach to the Triple Negative Breast Cancer in new drugs area
... advanced breast cancer were assigned to two sequential cohorts in a phase 2 ...BRCA-deficient breast cancers and show a favorable therapeutic index for a novel targeted treatment strategy in patients ...
5
The clinical promise of immunotherapy in triple-negative breast cancer
... Abstract: Triple-negative breast cancer (TNBC) is a heterogeneous disease with poorer outcomes compared to other breast cancer ...lung cancer, melanoma, and bladder ...
11
Androgen receptor expression in triple-negative breast cancer
... in breast carcinomas especially in metaplastic carcinoma, which although less frequent, is inserted into the differentiation pathway of progenitor/myoepithelial cells of the mammary carcinogenesis [59] ...
80
Update on triple-negative breast cancer: prognosis and management strategies
... Abstract: Triple negative breast cancer (TNBC) is a heterogeneous disease comprehending different orphan breast cancers simply defined by the absence of ...all breast cancers ...
10
Recent advances in nanotheranostics for triple negative breast cancer treatment
... PD-L1-positivetriple-negative breast cancer (TNBC) ...anti- cancer activity and prolonged the progression-free sur- vival among patients with metastatic triple-negative ...
22
Controversial issues in the neoadjuvant treatment of triple-negative breast cancer.
... Abstract: Triple-negative breast cancer (TNBC), as a collective group of heterogenous tumours, displays the highest rate of distant recurrence and lowest survival from metastatic disease ...
15
Triple negative breast cancer: an Indian perspective
... Introduction: Breast cancer is the most common female cancer in the ...world. Triple negative breast cancer (TNBC) is a recently identified biological variant with ...
5