TSG-6
TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
... Previously, we have shown that ASC-CCM could pre- serve retinal barrier function in an in vitro model [11]. To address the role of TSG-6 in this pathway, trans- endothelial electrical resistance (TER) was ...
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Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix
... 䡠 TSG-6 formation (40), requiring a particular sulfation pattern in the glycosaminoglycan linkage region in order for I ␣ I to act as a substrate (24); chondroitin (91, 92) and the CS chain of bikunin 䡠 CS ...
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The inhibitory effect of mesenchymal stem cell on blood–brain barrier disruption following intracerebral hemorrhage in rats: contribution of TSG-6
... of TSG- 6 [21]. TSG-6 can play a role by inhibiting components in the inflammatory network of proteases [56], suppressing neutrophil migration into the site of inflammation [57], and ...
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Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix
... by TSG-6 (37, 39, ...that TSG-6 is not a major participant in the structural stabilization of the cumulus matrix through its direct cross-linking of HA chains, as has been sug- gested ...
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Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6
... alpha; TSG-6: Tumor necrosis factor alpha-stimulated gene-6; TSG-6 siRNA: Tumor necrosis factor α stimulated gene-6 small interfering ribonucleic acid; TUNEL: Terminal ...
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TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice
... APC: Allophycocyanin; cAT-MSC: Canine adipose tissue-derived mesenchymal stem cell; cPBMC: Canine peripheral blood mononuclear cell; DSS: Dextran sulfate sodium; ELISA: Enzyme-linked immunosorbent assay; FITC: ...
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Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6
... of TSG-6 in microglia, we first evaluated its effect on NF-κB ...with TSG-6 significantly decreased the level of activation of these kinases in LPS-stimulated micro- ...of TSG-6 ...
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Liver-targeted delivery of TSG-6 by calcium phosphate nanoparticles for the management of liver fibrosis
... the TSG-6 loading capacities of CaP@BSA NPs was determined by ...The TSG-6 loading efficiency and loading capacity of CaP@BSA NPs were ...initial TSG-6 concentration of 125 ...
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TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice
... all, TSG-6 plays an important role in ER stress-induced apoptosis and early phase of inflamma- tory response, probably by reducing the ER stress and inhibiting the NF-κB pathway in ...
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TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway
... Recently, TSG-6 has emerged as a protective regulator against inflammation in cornea injury, peritonitis, auto- immune diabetes, asthma, and other inflammation-asso- ciated ...diseases. TSG-6 ...
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Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model
... the TSG-6 treatment, an observation that is consistent with the anti-inflammatory effects of the protein ...of TSG-6 in many different cells, but TSG-6 creates a negative ...
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Gene expression induced by interleukin 17 in fibroblast like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan binding protein TSG 6
... To gain knowledge about the effects of IL-17 in SFCs of patients with RA, we studied the expression and modula- tion of selected genes differentially expressed after stimu- lation with IL-17. Our results show that IL-17 ...
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Systematic implantation of dedifferentiated fat cells ameliorated monoclonal antibody 1-22-3-induced glomerulonephritis by immunosuppression with increases in TNF-stimulated gene 6
... of TSG-6 protein was significantly higher in DFAT cells than in ...of TSG-6 mRNA in MCs cocultured with DFAT cells was significantly higher than in mesangial cells or DFAT cells ...with ...
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Tumor necrosis factor-inducible gene 6 promotes liver regeneration in mice with acute liver injury
... study, TSG-6 released by MSCs suppressed the proinflammatory signal and reduced the collagen accumulation which was likely due to the inactiva- tion of hepatic stellate cells by TSG-6 in the ...
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Novel mechanism for mesenchymal stem cells in attenuating peritoneal adhesion: accumulating in the lung and secreting tumor necrosis factor α-stimulating gene-6
... MSCs, TSG-6-siRNA-MSCs, or TSG-6- siRNA-NC-MSCs injection intravenously at 24 hours after scraping (n = 3 in each group at each time ...of TSG-6 in serum was performed by ELISA ...
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6220T-TSG User Manual
... Tone Commander 6220T-TSG ISDN Telephone is an easy to use multiline terminal with advanced automatic setup capabilities. This model meets the requirements for TSG-6 certification, guaranteeing on- ...
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Discontinuous Parsing with an Efficient and Accurate DOP Model
... Representing all possible fragments of a treebank is infeasible, since the number of fragments is exponen- tial in the number of nodes. A practical solution is to define a subset. A method called Double- dop (2dop ; ...
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An integrative approach to building professional attributes in a first year nursing course: description and preliminary analysis of academic numeracy
... a TSG is to gather participants interested in a certain topic in mathematics ...each TSG will review, select and organize contributions, some by invitation and some submitted by interested participants, ...
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2. Epigenetics-beyond the DNA sequences-current scenario
... are one of the main causes of the breast cancers where metabolites resulted by foods and drinking water may act as endocrine disruptors causing epigenetic hormonal regulation towards increased breast cancer risk. ...
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TSG: a new algorithm for binary and multi-class cancer classification and informative genes selection
... The TSG classifier achieved better leave- one-out cross validation accuracy for the binary classifica- tion than TSP or k-TSP ...our TSG classifier gives comparable performance or outperform TSP family and ...
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