tubular epithelial cells
Original Article PAK4 enhances TGF-β1-induced epithelial-mesenchymal transition through activating β-catenin signaling pathway in renal tubular epithelial cells
... renal tubular epithelial cells plays a crucial role during the process of renal interstitial fibrosis ...in tubular epithelial cells of human kidney biopsies with different ...
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The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1
... proximal tubular epithelium is thought to play a key role in the initia- tion and progression of renal ...proximal tubular epithelial cells (FPTEC), comparing them to human primary renal epi- ...
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Hypoxia is a pro-fibrogenic stimulus for human renal tubular epithelial cells
... endothelial cells but may have more widespread ...HeLa cells is mediated by increased transcription o f the c-fos, jun-D and c-jun genes in response to changes in cellular redox status, although the ...
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Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells
... A-treated cells. Confocal microscopy of untreated cells re- vealed large nuclear inclusions with strong VP1 signals surrounded by LT-ag staining ...Vero cells (multiplicity of infection [MOI] of 1) ...
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TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells
... agent). Cells with increased ΔR/R0, in response to different stimuli, were counted from fields containing 30 to 100 cells taken from 3 to 4 separate ...First, cells were superfused with the control ...
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Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease
... HK-2 cells (provided by Theo Borghuis, Division of Medical Biology, UMCG) were cultured in growth medium consisting of low-glucose (1 g/l) DMEM supplied with 10% FCS, 1% 100 IE penicil- lin/100 μg streptomycin ...
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PATHOLOGICAL EFFECT OF CITRININ AND AFLATOXIN IN BROILER CHICKEN
... the tubular epithelial cells in kidneys, degenerative changes in hepatocytes, microgranuloma, periportal fibrosis, periductular mononuclear cell infiltration, fatty degeneration, focal necrosis and ...
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Generation of TALEN-mediated FH knockout rat model
... of tubular epithelial cells around glomeruli were identified in the FH+/– kidney, and these anaplastic cells were comparatively positive for Ki67, p53 and Sox9, and such findings are most ...
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Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel
... of tubular epithelial cells, especially PTECs, play an important role in the progression of DKD (Wakino et ...beta cells due to sustained enhancement of Ca 2+ influx and stimulated production ...
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Protective effect of intrarenal calcium membrane blockers before or after renal ischemia Functional, morphological, and mitochondrial studies
... Since intracellular calcium Ca++ in vascular smooth muscle and renal tubular epithelial cells could be involved in renal vasoconstriction 7 and epithelial cell necrosis 8, respectively, [r] ...
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Microvascular pericytes in healthy and diseased kidneys
... endothelial cells of healthy ...injured tubular epithelial cells and macrophages activate the endothelial cells, which produce PDGF and ...Injured tubular epithelial ...
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Predominant role for C5b 9 in renal ischemia/reperfusion injury
... proximal tubular epithelial cells have deficient expression of the C regula- tory proteins CD55 and CD46 (53) and can activate the alternative pathway spontaneously at low concentrations of serum ...
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Original Article Adult Stem Cell-like Tubular Cells Reside in the Corticomedullary Junction of the Kidney
... respectively. Cells were cultured using a previously described procedure with modifications ...dispersed tubular epithelial cells. The dispersed cells were plated on plastic culture ...
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Original Article Clinicopathological characteristics and intrarenal angiotensin II expression in X-linked Alport syndrome
... foam cells of XLAS, and the expression correlated with local tubulointerstitial ...First, tubular epithelial cells resorb AngII from glomerular filtration via the AT 1 R [21, ...
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TGF β Mediated Epithelial Mesenchymal Transition in Autosomal Dominant Polycystic Kidney Disease
... that epithelial-mesenchymal transition (EMT) can occur in tubular epithelial cells, which are able to migrate to the interstitium and produce extracel- luar matrix ...-SMA)+ cells is ...
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Original Article The differential expression of TGF-β1, ILK and wnt signaling inducing epithelial to mesenchymal transition in human renal fibrogenesis: an immunohistochemical study
... Abstract: Epithelial-to-mesenchymal transition (EMT) is a process for fully differentiated epithelial cells to undergo a phenotypic change to fibroblasts via diverse intracellular signaling ...
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A poles apart applications of somatostatin hormone
... The human kidney expresses several subtypes of sst mRNA, with a quite specific expression of sst5 in tubular epithelial cells. Sst1 and sst2 are have been found in the tubules and glomeruli of human ...
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Cyclic helix B peptide inhibits ischemia reperfusion induced renal fibrosis via the PI3K/Akt/FoxO3a pathway
... TGF-β-stimulated tubular epithelial cells (TCMK-1 and HK-2) ...the epithelial-mesenchymal transition of tubular cells, possibly through suppression of the PI3K/Akt path- way and ...
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Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production
... the tubular epithelial cells during the reoxygenation period, whereas in the renal medulla, iNOS immunoreactivity displayed only weak intensity, suggesting that iNOS expression induced by ...
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Original Article Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse
... Cisplatin or cis-diamine-dichloroplatinum (II) (CDDP) is a platinum-containing anti-cancer drug widely used against multiple solid tumors. Many side effects such as ototoxicity, gastro- toxicity, myelosuppression, and ...
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