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Tumor Cells

Characteristics of circulating tumor cells in organ metastases, prognosis, and T lymphocyte mediated immune response

Characteristics of circulating tumor cells in organ metastases, prognosis, and T lymphocyte mediated immune response

... Circulating tumor cells (CTCs) possess profound influence on tumor metastases and disease ...T cells was ...circulating tumor cells (EMCTCs) was higher than that of epithelial ...

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Interaction of MSC with tumor cells

Interaction of MSC with tumor cells

... for tumor-initiating cells (TIC) in mammary carcinoma also termed cancer stem cells (CSC) with increased expression of mesenchy- mal characteristics including vimentin, fibronectin and N-cadherin ...

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Human mesenchymal stem cell-derived iron oxide exosomes allow targeted ablation of tumor cells via magnetic hyperthermia

Human mesenchymal stem cell-derived iron oxide exosomes allow targeted ablation of tumor cells via magnetic hyperthermia

... of tumor cell proliferation in the absence of 5-Fc and for proliferation inhibition activity in the presence of 5-Fc using the Incucyte system and MTT ...of tumor cell death after aMF ...Uc-Mscs/Fe ...

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The impact of γ-irradiation on the induction of bystander killing by genetically engineered ovarian tumor cells: implications for clinical use

The impact of γ-irradiation on the induction of bystander killing by genetically engineered ovarian tumor cells: implications for clinical use

... these cells in the presence of ganciclovir provoked bystander killing, but with limited cytotoxic activity in vivo ...STK cells, injected in the vicinity of the patient’s tumor bulk, could make ...

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Circulating Tumor Cells as a Tool for Assessing Tumor Heterogeneity

Circulating Tumor Cells as a Tool for Assessing Tumor Heterogeneity

... in tumor cells and TME components (mainly immune cells) in breast ...to tumor development and the response to cancer therapy ...the cells’ transcriptomic ...

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Antileukotactic properties of tumor cells

Antileukotactic properties of tumor cells

... A chemotactic factor inactivator (CFI) has been found in extracts of Walker and Novikoff tumor cells maintained in rats. The CFI directly inactivates the bacterial chemotactic factor as well as the ...

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Gangliosides shed by tumor cells enhance tumor formation in mice

Gangliosides shed by tumor cells enhance tumor formation in mice

... of tumor cell membrane gangliosides in tumor formation was probed using a series of cloned murine AKR lymphoma cell ...lines. Tumor formation was directly related to high expression and shedding of ...

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Interaction of tumor cells with the microenvironment

Interaction of tumor cells with the microenvironment

... stem cells (MSC), and a variety of different immune cells including lymphocytes and tumor-associated macro- phages ...the tumor stroma determine not only cancer growth and metastasis but may ...

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Elimination of mouse tumor cells from neonate spermatogonial cells utilizing cisplatin-entrapped folic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles in vitro

Elimination of mouse tumor cells from neonate spermatogonial cells utilizing cisplatin-entrapped folic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles in vitro

... green cells indicate the TUNel-positive apoptotic ...apoptotic cells increased after 48 hours in the group treated with 2 mg/ ml cDDP/Plga NPs: (A) TUNel assay; (B) DaPI staining; and (C) ...el4 ...

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Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing

Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing

... of tumor cells adjacent to blood vessels is one of the major elements to gain deeper penetration and diffusion of PEGylated liposome in tumor tissue (Figures 2 and ...5-FU-resistant tumor ...

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AN INSIGHT INTO BREAST CANCER METASTASIS TO BONE

AN INSIGHT INTO BREAST CANCER METASTASIS TO BONE

... certain tumor cell will selectively colonize a distant organ because of the presence of a favorable environment for their growth ...of tumor cells is because of its biological and molecular ...

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Cytokine therapy reverses NK cell anergy in MHC deficient tumors

Cytokine therapy reverses NK cell anergy in MHC deficient tumors

... NK cells provided therapeutic benefit in tumor-bearing mice by inducing activation of NK ...treated tumor-bearing mice with a combination of IL-12 and IL-18 or with an IL-2 mutant (H9 “superkine”) ...

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Differential expression of the epigenetic methylation related protein DNMT1 by breast cancer molecular subtype and stromal histology

Differential expression of the epigenetic methylation related protein DNMT1 by breast cancer molecular subtype and stromal histology

... % tumor cells; 2+, complete membranous staining, either uniform or weak in at least 10 % of tumor cells; and 3+, uniform, intense membranous staining in at least 30 % of tumor ...

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Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.

Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.

... CT26 tumor cells (16 10 6 , in 100 ml PBS) were subcutaneously injected into the neck area of 8–12 week old female BALB/c mice and 6 days thereafter, 100 mg ...dissected tumor area was measured using ...

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Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice

Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice

... immune cells, mediators of our defense system, to pro- mote tumor invasion and angiogenesis remain incompletely ...in tumor cells has been shown to promote tumor invasion and ...in ...

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A Computational Assessment of the Robustness of Cancer Treatments with Respect to Immune Response Strength, Tumor Size and Resistance

A Computational Assessment of the Robustness of Cancer Treatments with Respect to Immune Response Strength, Tumor Size and Resistance

... reduced tumor size more effectively than standard ...are tumor angiogenesis, immunosuppression due to Treg cells and tumor-secreted cytokines, and the emergence of treatment ...KRAS-mutant ...

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Case Report Granular cell tumor of the ampulla of Vater: report of a unique case with emphasis on immunohistochemistry for TFE3 antigen expression

Case Report Granular cell tumor of the ampulla of Vater: report of a unique case with emphasis on immunohistochemistry for TFE3 antigen expression

... no tumor markers or imaging characteristics that allow a preop- erative diagnosis for GCT, the diagnosis is based entirely on histopathological and immu- nohistochemical ...circumscribed tumor was located ...

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Search | Preprints

Search | Preprints

... [53,55], tumor-associated angiogenesis [30] due to upregulation of VEGF-A and tumor- associated lymphangiogenesis [56-59] due to upregulation of VEGF-C and ...on tumor and host cells, as ...

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Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance

Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance

... criteria, tumor stage, tumor site and preoperative therapy were ...paraffin-embedded tumor samples from these ...on tumor and stromal cells for HNPCC ...and tumor cells. ...

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Tumor infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

Tumor infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

... induce tumor-specific immune responses, in particular CTL responses, in many patients ...suppressor cells (MDSCs) are a source of the free radical peroxynitrite ...human tumor cells with PNT ...

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