• No results found

tumor microenvironment

Social networks help to infer causality in the tumor microenvironment

Social networks help to infer causality in the tumor microenvironment

... the tumor microenvironment—where different types of resident and infiltrating cells interact to carry out their functions, the complexity of the system demands a theoretical framework, such as statistical ...

10

Novel Therapeutic Targets in the Brain Tumor Microenvironment

Novel Therapeutic Targets in the Brain Tumor Microenvironment

... brain tumor of adults and children, diffusely invades within the non-neoplastic ...the tumor and constituents of its microenvironment are known to regulate malignancy, and heparan sulfate ...

8

Cellular interactions in the tumor microenvironment: the role of secretome

Cellular interactions in the tumor microenvironment: the role of secretome

... primary tumor cells recruit and activate non-transformed stromal cells, including fibroblasts, endothelial, inflammatory and immune system cells [22, 23], in order to promote a microenvironment favorable to ...

14

Exosomes in tumor microenvironment: novel transporters and biomarkers

Exosomes in tumor microenvironment: novel transporters and biomarkers

... exosomes: tumor‑derived exosomes; TEM: transmission electron microscope; TFPI: tissue factor pathway inhibitor; TGF: transforming growth factor; TME: tumor microenvironment; TSCC: tongue squamous ...

9

Tissue factor in tumor microenvironment: a systematic review

Tissue factor in tumor microenvironment: a systematic review

... the tumor microenvironment ...the tumor microenvironment, resulting in an immunosuppressive milieu [82] (Figure ...the tumor microenvir- onment may cause local ischemia and hypoxia, ...

8

Immune targets in the tumor microenvironment treated by radiotherapy

Immune targets in the tumor microenvironment treated by radiotherapy

... cells: Tumor infiltration of DCs and several other immune effector cells is carried out via several cytokines such as CXCL16, TNFα, IL-1β, IL-6 secreted by IR induction of tumor cells ...in tumor ...

17

Theranostic Probes for Targeting Tumor Microenvironment: An Overview

Theranostic Probes for Targeting Tumor Microenvironment: An Overview

... the tumor microenvironment ...promote tumor growth, invasion and ...enhancing tumor progression, it is vital to identify the different components in the ...

24

Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

... of tumor- derived SCF, inflammation, and germline Nf1 heterozygosity to neu- rofibroma development and provide insights for the design of future neurofibroma therapies in targeting its tumor ...

15

Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy

Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy

... Subsequently, tumor microenvironment modification by IMA treatment was investigated by immunofluorescence staining (Figure ...cause tumor vessel regression by stripping out pericytes in some ...

12

Immune mediators in the tumor microenvironment of prostate cancer

Immune mediators in the tumor microenvironment of prostate cancer

... both tumor cells and host ...the tumor is termed the tumor microenvironment (TME) ...either tumor- or host-derived ...target tumor cells through cytostatic or cytocidal activ- ...

8

Molecular targeting of liposomal nanoparticles to tumor microenvironment

Molecular targeting of liposomal nanoparticles to tumor microenvironment

... target tumor microenvironments ranging from animal studies to clinics will be dependent on their ability to target all aspects of the tumor microenvironment, including cancer stem ...of tumor ...

11

Tumor associated stromal cells as key contributors to the tumor microenvironment

Tumor associated stromal cells as key contributors to the tumor microenvironment

... In addition to CAFs/TAFs, there is growing evidence to support a TASC subtype derived exclusively from adipose tissue called cancer-associated adipocytes (CAAs) [4] (Fig. 1). Found at the invasive front of tumors, CAAs ...

11

A Review of Exosomes and their Role in The Tumor Microenvironment and Host-Tumor "Macroenvironment"

A Review of Exosomes and their Role in The Tumor Microenvironment and Host-Tumor "Macroenvironment"

... the tumor microenvironment (TME) and the hypothesis that exosomes may also generate a host-tumor “macroenvironment” beyond the TME through their miRNA and protein payloads, so to speak “fertilizing ...

5

Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

... immunosuppressive tumor micro- environment contains numerous potential therapeutic targets whose modulation could render the tumor microenvironment more immunologically ...the tumor ...

19

Effect of Stromal Cells in Tumor Microenvironment on Metastasis Initiation

Effect of Stromal Cells in Tumor Microenvironment on Metastasis Initiation

... where tumor cells reside is called the tumor microenvironment (TME), which consists of borders, blood vessels, lymph vessels, extracellular matrix (ECM), stromal cells, immune/inflammatory cells, ...

11

Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications

Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications

... entering tumor cells, the balance between positive and negative charges will be broken and thereby cause conformational changes, facilitating drug release in tumor ...of tumor microenvironment ...

11

Virulence genes are a signature of the microbiome in the colorectal tumor microenvironment

Virulence genes are a signature of the microbiome in the colorectal tumor microenvironment

... the tumor microenvironment suggests sev- eral alternative, though not mutually exclusive, hypoth- ...or tumor progression; another possibility is that these species are being enriched as the ...

12

A key role of GARP in the immune suppressive tumor microenvironment

A key role of GARP in the immune suppressive tumor microenvironment

... on tumor and T cells, we checked viability using 7-AAD (data not shown) and only viable cells were analyzed by flow ...inhibitory tumor microenvironment by decreasing GARP expression on melanoma ...

14

Osteoprotegerin rich tumor microenvironment: implications in breast cancer

Osteoprotegerin rich tumor microenvironment: implications in breast cancer

... TME: tumor microenvironment; ECM: extracellular matrix; OPG: osteoprotegerin; TNFR: tumor necrosis factor receptor; TRAIL: TNF related apoptosis inducing ligand; IBC: Inflammatory breast cancer; ...

15

Targeting the tumor microenvironment to enhance antitumor immune responses

Targeting the tumor microenvironment to enhance antitumor immune responses

... the tumor microenvironment ...of tumor-specific T cells by the peri- tumoral administration of CTLA-4-blocking antibodies in the lipid-based adjuvant montanide [213, ...approach, ...

23

Show all 9834 documents...

Related subjects