tumor-tissue endothelial cells
Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2
... the endothelial cells express trypsinogen 4, consistent with the notion that this isoform is expressed by extra-pancreatic tissues ...in tissue specificity, cellular localization, and extracellular ...
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Endothelial cells stimulated with tumor necrosis factor alpha express varying amounts of tissue factor resulting in inhomogenous fibrin deposition in a native blood flow system Effects of thrombin inhibitors
... in endothelial cell functions, such as upregulation of tissue factor, resulting in endothelial procoagulant activity which may play a role in disseminated intravascular ...TNF-alpha-stimulated ...
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Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers
... of tumor antigens and priming of CTLs is affected by matrikines via interactions with TLRs and DC ...186]. Endothelial cells, pericytes and adhesion molecules modulate trafficking and infiltration of ...
14
Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium
... the endothelial cells of primary soft tissue sarcomas did not affect vascular development or tumor ...the tumor vasculature between tumors derived from cell lines and autochthonous ...
15
Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.
... Human tumor and metastases specimens were obtained from tumor patients at the Klinikum rechts der Isar, TU ...in tumor regression without the induction of adverse effects. (A) CT26 ...
11
Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma
... of endothelial progenitor cells into endothelial cells [20, ...of tumor cells, which acquire characteristics normally restricted to ...
19
Anti-tumor Effects of Targeted Follicle-stimulating Hormone-lytic Peptide Conjugates in Prostate Cancer (PC-3) Xenograft Mouse Model
... vascular endothelial cells, in sections from the tumor tissue samples obtained from nude mouse ...vascular endothelial cells at a dilution of ...
8
Original Article Clinicopathological features of Kaposiform hemangioendothelioma
... intermediate tumor of endothelial origin in childhood, is often associated with Kasabach-Merritt phenomenon ...spindleshaped endothelial cells and slitlike vascular channels with irregular ...
8
Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing
... into tumor tissue is problematic. Structural abnormalities, tumor vasculature heterogeneity, and elevated intratumor pressure impose barriers against the preferential accumulation of ...
10
Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice
... these tumor lines. Tumor cells over-expressing tissue factor released more (compared with control transfectants) mitogenic activity for endothelial cells in parallel with ...
9
Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and treatment
... neutrophils, tumor cells, platelets and endothelial cells result in ...blue), tumor (green), platelet (lavender), and endothelium ...primary tumor site releases extracellular ...
13
PubMedCentral-PMC5158050.pdf
... BMP ligands initiate signal transduction by binding a hetero-tetrameric receptor comprised of two dimers of type 1 and type 2 receptors [20]. Among a group with specificity for TGFβ and/or BMP signaling, BMPR1A, BMPR1B ...
13
DESIGN AND SYNTHESIS OF NOVEL CATIONIC LIPOPEPTIDES AND AMPHIPHILES FOR USE IN ANTI-ANGIOGENIC CANCER THERAPY AND DNA VACCINATION
... presenting cells such as dendritic cells (DCs) and macrophages, selectively binds molecules or microorganisms carrying sugars such as mannose, fucose, N- acetylglucosamine and glucose on their surface ...
10
Immunohistochemical Expression of VEGF in Gastric Tumors
... (8) Raica M1, Mogoantal, Cimpear AM, Alexa A, Ioanovicis, Margaritescu C, Lazar D, Izvernariu D, Immunohistological expression of vascular endothelial growth factor (VEGF) in intestinal type gastric carcinoma . ...
9
Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer
... the tumor microenvironment along with their secreted cytokines, such as IL-6, interact with prostate cancer cells and play an important role in neuroendocrine differentiation and the prognosis of prostate ...
14
Tumor dormancy: potential therapeutic target in tumor recurrence and metastasis prevention
... life. Tumor cell dormancy may help to explain treatment resistance and recurrence or metastatic ...of tumor cells may help in discovering ways to maintain the dormant state or permanently eliminate ...
8
Tissue factor expression by endothelial cells in sickle cell anemia
... these cells were blocked with 3% BSA before testing with the anti–Factor VII/VIIa antibody, this result incidentally excludes the possibility that bovine Factor VII/VIIa contami- nating BSA would contribute to our ...
7
Binding of tissue plasminogen activator to cultured human endothelial cells
... Therefore, endothelial cells can modulate hemostatic and thrombotic events at the cell surface by providing specific binding sites for activation of ...
9
Tissue engineering whole bones through endochondral ossification: Regenerating the distal phalanx
... Novel strategies are urgently required to facilitate regeneration of entire bones lost due to trauma or disease. In this study, we present a novel framework for the regeneration of whole bones by tissue ...
13
Double target for tumor mass destruction
... eter, increased leakiness, and capillary microaneurysms. During normal development, PDGF-B secreted (and bound) by vascular ECs signals to neighboring PC progenitors express- ing PDGFR-β to promote the recruit- ment of ...
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