tumor uptake
![Comparative study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
Comparative study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging
... kidney uptake was higher at all times for the dimer, while muscle uptake was simi- lar for both ...cellular uptake studies predicted higher tumor uptake for 64 ...PC3 tumor ...
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A convenient and efficient total solid-phase synthesis of DOTA-functionalized tumor-targeting peptides for PET imaging of cancer
... identical tumor uptake value ...The tumor uptake values of other BN pep- tides varied from ...vivo tumor receptor specificity of these radiolabeled BN peptides for BN/GRP ...
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Nanogels from Metal-Chelating Crosslinkers as Versatile Platforms Applied to Copper-64 PET Imaging of Tumors and Metastases
... passive tumor uptake, long blood circulation time, and relatively low uptake in the liver and spleen suggest that they represent a promising platform for molecular imaging and drug ...
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Effects of erlotinib therapy on [11C]erlotinib uptake in EGFR mutated, advanced NSCLC
... TKI uptake after disease progression appears, and consequently, may aid in deciding whether or not to discontinue EGFR TKI ...on tumor [ 11 C]erlotinib uptake need to be investigated ...and ...
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Neuropilin-1 drives tumor-specific uptake of chlorotoxin
... in tumor regression ...where tumor regression was observed in WT versus minimal antitumor activity in KO tumors ...with tumor regression observed in both models ...on tumor cells enhances the ...
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Photodynamic Therapy Induced Enhancement of Tumor Vasculature Permeability Using an Upconversion Nanoconstruct for Improved Intratumoral Nanoparticle Delivery in Deep Tissues
... intratumoral uptake of different particles, Human Serum Albumin (HSA) and gold nanoparticles instead of liposomal nanoparticles were used and their accumulation within tumors was ...enhanced uptake in ...
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Intratumoral 18F-FLT infusion in metabolic targeted radiotherapy
... of tumor therapies [3, 7], and it has found limited use for tumor therapy follow-up in clinical trials [8, ...F-FLT tumor uptake is generally lower than that of 2-deoxy-2-[ 18 ...
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Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment
... treated tumor tissue was much greater than the theoretical DOX content (in direct proportion to the TopFluor® PC content), as shown in Figure ...the tumor uptake of vesicles but also triggered the ...
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68Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma
... maximum tumor uptake was selected by drawing a 3D-volume of interest (VOI) around the whole tumor ...area. Tumor regions of interest (ROIs) were defined in 2 ...
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Integrin αvβ3-Targeted Radiotracer 99mTc-3P-RGD2 Useful for Noninvasive Monitoring of Breast Tumor Response to Antiangiogenic Linifanib Therapy but not Anti-Integrin αvβ3 RGD2 Therapy
... the lateral tail vein. Anesthesia was induced using an air flow rate of 350 mL/min and approximately 3.0% isoflurane. After induction of anesthesia, the air flow rate was reduced to 250 mL/min with approximately 2.0% ...
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Enhanced Synergism of Thermo-chemotherapy For Liver Cancer with Magnetothermally Responsive Nanocarriers
... tissues, tumor tissues are rich in blood vessels and have a wider blood vessel gap, poor structural integrity, and lack lymphatic drainage, which is responsible for their selective high permeability and retention ...
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Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
... Radiotracer uptake studies were performed in monolayer cultures of DU-145 prostate cancer cell lines, which were obtained from ATCC (Manassas, VA, ...ment, tumor cells exposed to a medium containing (+)-[ ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... The uptake experiment was terminated at each time point by aspirating the test samples and washing the cell monolayers with ice-cold PBS three ...The uptake of DOX-MNPs or free DOX can be visualized by ...
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Self-assembled micelles of amphiphilic poly(L-phenylalanine)-<em>b</em>-poly(L-serine) polypeptides for tumor-targeted delivery
... the uptake of PFS micelles by Huh-7 cells, which indicated that at least a part of PFS micelles were uptaken by cells via clathrin-mediated ...the uptake of PFS micelles, which illustrated that caveolae- ...
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Imaging of Hsp70-positive tumors with cmHsp70.1 antibody-conjugated gold nanoparticles
... an uptake of gold nanoparticles, which could be visualized by light microscopy (data not ...visible uptake of ...the tumor cells bearing Hsp70 on their membrane showed an uptake of Au- Hsp70 ...
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Evaluation of a 3-hydroxypyridin-2-one (2,3-HOPO) Based Macrocyclic Chelator for 89Zr4+ and Its Use for ImmunoPET Imaging of HER2 Positive Model of Ovarian Carcinoma in Mice
... for tumor, blood, liver and bone obtained during PET imaging are shown at Figure ...liver uptake of 1-labeled antibodies compared to 89 Zr-DFO-labeled ...
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Tumor heterogeneity measurement using [18F] FDG PET/CT shows prognostic value in patients with non-small cell lung cancer
... lying tumor biology and heterogeneity in specific tumor biology ...characteristics. Tumor heterogeneity refers to features at a cellular level ...and tumor metabolism) as well as to molecular ...
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Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives
... the tumor, penetration of Abs into the tumor can still be hampered by some physiological barriers, such as high interstitial pressure and a ‘binding site barrier’ ...within tumor masses, fragments of ...
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<p>SUVmax and metabolic tumor volume: surrogate image biomarkers of KRAS mutation status in colorectal cancer</p>
... were reconstructed by attenuation and iterative reconstruc- tion, then multi-layered, multi-imaged, and merged with the CT images to ensure image clarity. This procedure was conducted by manufacturer review workstation ...
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ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy
... the tumor targeting delivery of anti-cancer drugs/gene, due to reaction of PBA with sialic acid (SA) over-expressed on the tumor cells [26, ...for tumor targeting in this ...
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