Tumor vessels
pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth
... Occluding tumor blood supply by delivering the extracellular domain of coagulation-inducing protein tissue factor (truncated tissue factor, tTF) to tumor vasculature has enormous potential to eliminate ...
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Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice
... of tumor growth by Sox17 ...early tumor growth — there was no growth inhibition when Sox17 was deleted during late tumor growth in the mouse model we ...a tumor environ- ment that was ...
15
Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity
... that tumor xenografts treated with lena- lidomide in association with 5-FU presented a clear trend towards the (re)differentiation of single cells and global tissue architecture, resembling features of nor- mal ...
12
Desacetylvinblastine Monohydrazide Disrupts Tumor Vessels by Promoting VE-cadherin Internalization
... Given that endothelial hyperpermeability contributes to vascular leakage [21, 25], we next investigated whether DAVLBH-mediated disruption of tumor vessels is associated with its effect on endothelial ...
15
Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery
... Prior to administration of particles, mice were positioned on a heated stage for a suitable position to image tumor vessels as previously described[49, 50]. Tumor imaging was performed by exposing ...
15
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
... glioma vessels, we analyzed the fraction of blood vessels positive for MMRN2 (Figure 9A) and fibronectin (Figure 9B) in glioma tissue microarrays, containing a total of 235 samples of human control brain ...
19
Percutaneous injection of an alcoholic embolizing emulsion as an alternative preoperative embolization for spine tumor
... The anterior spinal artery for the cervical cord arose from the right VA below the origin of tumor vessels; very thin tumor vessels arose from the left VA Fig 1C and 1D.. On the basis of[r] ...
5
Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice
... in tumor vessels could be targeted transiently to the luminal surface of the endothelium ...to tumor endothelial cells and develop tools to modulate angiogenesis in tumors, chronic in- flammation, ...
14
Two-stage oxygen delivery for enhanced radiotherapy by perfluorocarbon nanoparticles
... In tumor, vascular endothelial cells are fewer and irregularly ...the tumor, leading to reduced endothelial cell tight junctions and increased endothelial cell damage [36, ...blood vessels [36, ...
14
Ultrasound sonication with microbubbles disrupts blood vessels and enhances tumor treatments of anticancer nanodrug
... the tumor growth was significantly inhibited for the PLD group, and the tumors even shrank significantly for the PLD + MBs + US ...of tumor vessels and hemorrhage, so that there would not have been ...
10
Double target for tumor mass destruction
... of tumor blood vessels, inhibition of tumor angiogenesis may provide an efficient strategy to slow down or block tumor ...a tumor mass depends on molecular, cellular, and structural ...
5
Expression of Endoglin in Bladder Carcinoma of Iraqi Patients
... It has a low expression level in the resting endothelial cells, but ot is highly expressed in the endothelial cells at sites of active angiogenesis such as tumor vessels, inflamed tissues [3, 4].Endoglin is ...
6
Tumor refractoriness to anti-VEGF therapy
... blood vessels with a investment of pericytes expressing alpha smooth muscle actin (α-SMA) ...and tumor vessels covered by pericytes are less sensitive to VEGF blockade ...with tumor ...
10
Dunleavey_unc_0153D_15928.pdf
... between tumor cells and endothelial cells in vitro as well as in tumors, through imaging or traditional barrier function studies (Privratsky and Newman 2014) could help explain whether PECAM-1 homophilic binding ...
138
"Primary" aggressive chondroblastoma of the humerus: a case report
... 'Atypical' indicates features of chondroblastoma with hemangiopericytoma like areas or presence of myxoid substance or spindle cells arranged in storiform pattern [6]. Unfortunately these 'atypical' features are not good ...
6
Malignancy Associated Vessel Tortuosity: A Computer Assisted, MR Angiographic Study of Choroid Plexus Carcinoma in Genetically Engineered Mice
... Once cancer is established, growth is rapid and leads to the emergence of massive cancers that occupy close to the entire ventricular system, expand the skull, and produce death within a matter of weeks. Figure 4 ...
8
The blood brain barrier: an important concept in neuroimaging
... These include an increase in the number of capillaries except in avascular areas 165; an increase in the overall diameter of the lumen of tumor blood vessels compared with normal brain b[r] ...
22
Original Article Clinicopathology significance of podoplanin immunoreactivity in esophageal squamous cell carcinoma
... patients with cutaneous squamous cell carci- noma [11]. The more significant finding of this study was D2-40 cellular positivity in 31.8% ESCC specimens and it was an increased risk of LNM, which was in accordance with ...
11
Case Report Primitive myxoid mesenchymal tumor of the infancy in abdominal cavity: report of a rare case
... mesenchymal tumor of the infancy (PMMTI) is an extremely rare soft tissue ...the tumor consisted of primitive spindle or polygonal cells dispersing in a myxoid background with delicate blood ...
8
Monitoring of tumor vascular normalization: the key points from basic research to clinical application
... of tumor vascular normalization, which limits the ability of guiding traditional ...detecting tumor vascular normalization from studies and discussed the questions that must be faced in the clinic (Table ...
10