tumour angiogenesis
TAFIa is a Novel Inhibitor of Tumour Angiogenesis in Breast Cancer
... through tumour angiogenesis differ from blood vessels formed through normal ...by tumour angiogenesis do not become quiescent, and the constant growth of new blood vessels within a ...
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The dual effect of mesenchymal stem cells on tumour growth and tumour angiogenesis
... in angiogenesis, we decided to evaluate the influence of hMSCs on tumour ...the tumour vasculature, characterised by a decrease in the number of blood vessels and an increase in the vessel size, ...
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Tumour angiogenesis in Epstein-Barr virus-associated post-transplant smooth muscle tumours
... of angiogenesis-related factors in ...hypoxia-inducible angiogenesis such as HIF1A, VEGFA, VEGFC, VEGFR1/FLT1, VEGFR2/KDR and FGFR1/FLT2 were expressed at low ...
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Role of genetic polymorphisms in tumour angiogenesis
... of angiogenesis. FGFs promote tumour cell mitosis and angiogenesis and inhibit apoptosis (Powers et al, ...in tumour angiogenesis and their inhibition represses tumour growth ...
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The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer
... of tumour cell angiogenesis, proliferation, invasion, and metastasis [32, 40, 44 – ...domain-promoted tumour angiogenesis and metastasis may be partly due to the activation of ...
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Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo.
... We have now shown that in C6 gliomas in the absence of NO, endogenous DDAH I overexpression did not alter tumour growth or vascular development. Our data rein- force the hypothesis that regulating DDAH I ...
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Host microenvironment in breast cancer development Inflammatory and immune cells in tumour angiogenesis and arteriogenesis
... differentiation. Tumour hypoxia is an important stimulus for extravasation of mono- cytes [14], which migrate into the tumour tissue along gra- dients of chemoattractants, and these TAMs become immobilized ...
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Breast tumour angiogenesis
... in angiogenesis, glycolysis, erythropoiesis and apoptosis ...various tumour types, with high levels influencing the growth rate and metastatic potential of these ...both tumour cells [38] and in ...
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EXPERIMENTAL MODELS TO STUDY TUMOUR ANGIOGENESIS – IN VITRO, EX VIVO AND IN VIVO APPROACH
... cancer, angiogenesis is required for tumor survival and ...on angiogenesis led to the idea that blocking tumor nourishment could be one of the ways to avoid its ...In-vitro angiogenesis assays are ...
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Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways
... Significant advances have been made in the treatment of metastatic colorectal cancer (mCRC) [9]. Refinements to cytotoxic chemotherapy regimens have incrementally improved median life expectancy in patients with mCRC, ...
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Tissue factor, angiogenesis and tumour progression
... of angiogenesis- stimulating ...pancreatic tumour cells and keratinocytes) to FVIIa led to increased gene expression of VEGF [56,57], urokinase-type plasminogen activator receptor [58], early growth ...
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Multi-scale mathematical modelling of tumour growth and microenvironments in anti-angiogenic therapy
... 3D tumour modelling is utilized to detail the mechanisms of tumour growth and ...solid tumour and the structural proper- ties of the vascular ...of tumour cells with correspond- ing metabolic ...
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... in angiogenesis, haematopoiesis, haemodynamics, and vascular ...and tumour angiogenesis ...of angiogenesis within its various glandular compartments ...
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Differentiation of angiogenic burden in human cancer xenografts using a perfusion type optical contrast agent (SIDAG)
... of tumour tissue, because the microvascular hyperpermeability observed in carcinomas increases with increasing tumour grade ...located tumour-associ- ated fluorochrome ...
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Quantification of Microvessel Density in Breast Carcinomas Based on Immunohistochemistry
... of tumour angiogenesis [17]. . They revealed that tumour microvessels can be highlighted with help of immunohistochemistry, by staining the tumour sections with an antibody against antigen ...
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... stimulate angiogenesis are basic fibroblast growth factor, epidermal growth factor, interleukin 1, interleukin 2, transforming growth factor alpha, transforming growth factor beta, tumour necrosis factor ...
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A Heterogeneous In Vitro Three Dimensional Model of Tumour-Stroma Interactions Regulating Sprouting Angiogenesis
... the tumour microenvironment, including endothelial cells, fibroblasts and in some instances tumour cells ...therefore tumour angiogenesis, through increased transcriptional activation ...a ...
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XI SEMINARIO NAZIONALE PER DOTTORANDI IN FARMACOLOGIA E SCIENZE AFFINI
... Tumour angiogenesis promoted by different stimuli as vascular endothelial growth factor (VEGF) is a fundamental step of tumour growth and progression. The aim of this study was: 1) to [r] ...
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Macrophages promote angiogenesis in human breast tumour spheroids in vivo
... for tumour angiogenesis and maintenance of vessel integrity has been demonstrated (Borgstrom et al, 1996; Lichtenbeld et al, ...of tumour angio- genesis, provide evidence that new functional vessels ...
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Noninvasive assessment and quantification of tumour vascularisation using MRI and CT in a tumour model with modifiable angiogenesis – An animal experimental prospective cohort study
... The MRI protocol contained morphological and func- tional techniques. T2-weighted imaging served for co- localisation and tumour volumetry, the latter was obtained by manual segmentation. For visualisation of ...
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