tumour cell
Investigating citrullinated proteins in tumour cell lines
... gland epithelial cells and MCF-7 breast cancer cells [13]. Therefore, the identification of citrullination substrates is helpful for understanding the pathogenic mechanisms of PADs during tumorigenesis. Thus far, ...
8
Identification of circulating tumour cell subpopulations
... Circulating tumour cells cannot be grown on slides however, making staining in so- lution or the use of cytospin ...aspiration, cell loss is ...blood cell based on size and morphology, whilst it ...
56
The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer
... microenvironment. In the present study, the prognostic role of ph-STAT1 and ph-STAT3 tumour cell expression in different molecular subtypes was examined. Ph-STAT1 and ph-STAT3 were significant predictors of ...
15
Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness
... allowed tumour cell and CAF populations to be isolated by FACSorting and directly lysed for gene expression profiling ...the tumour cells isolated from the less aggressive 4T07 tumours with low-level ...
14
PARP inhibitor combination therapy.
... the tumour; presumably these mutations produce a larger number of neo-antigens, which can be recognised by the immune system (Rizvi et ...ovarian tumour cell line grown in vivo in the peritoneum ...
42
Modelling the immune response to cancer : an individual based approach accounting for the difference in movement between inactive and activated T cells
... either tumour specific antigens (TSAs), tumour asso- ciated antigens (TAAs) or cancer/testis antigens ...only tumour cells produce, that is, no normal cells will produce ...by tumour cells, ...
23
P2X7 receptors are a potential novel target for anti-glioma therapies
... analogue of brilliant blue FCF (FD&C blue dye No. 1) which is a synthetic dye approved by the Food and Drug Administration as a food additive considered as one of the safest dyes currently available, with no tox- ...
10
A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility
... Histopathological tumour cell percentage assessment was done based on (H/E) coloured tumour ...breast tumour samples was per- formed using custom-made Agilent 44K high-density microarrays ...
8
Comparing stochastic differential equations and agent based modelling and simulation for early stage cancer
... of tumour cells when compared to the ...of tumour cells over time in the ABMS simulation, which does not happen in the Gillespie ...the tumour cells agents are defined according to the mathematical ...
18
Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma –results from the UK MRC OE02 trial
... of tumour cells and intratumoural stroma (extracellular matrix, fibroblasts, vessels, immune cells ...transformation, tumour invasion and metastasis (for review see Hanahan et ...inhibiting tumour ...
11
Cancer stem cells – the current status of an old concept: literature review and clinical approaches
... heterogeneous cell populations. The cancer stem cell (CSC) hypothesis assumes that a tumour is hierarchically organized and not all of the cells are equally capable of generating descendants, ...
9
A 90Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy
... observed tumour regrowth at about day ...of cell de- generation was observed at day 28; furthermore, the shape and size of tumour cells appeared to be the same as those observed at day ...[22]. ...
10
Investigating mathematical models of immuno interactions with early stage cancer under an agent based modelling perspective
... of tumour cells is also observed in the ABMS ...of tumour cells over ...of tumour cells agents are defined according to the mathematical model, when the tumour cell population grows, the ...
38
Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics
... expressing tumour cells need only a short incubation with GCV (16 h), to bring about almost 100% tumour cell death over the subsequent 3-days of culture without ...and tumour regression in ...
11
The roles of hypoxia on neuroblastoma cell migration and invasion
... of tumour cell aggression (Wojtkowiak et ...of tumour cell aggression in studies of human colon cancer, glioblastoma and breast cancer (McIntyre et ...
115
Perivascular epitheloid cell tumour (PEComa) of the retroperitoneum – a rare tumor with uncertain malignant behaviour: a case report
... of tumour cells with a uniform, spindle ...the tumour dis- played fascicles and nests of elongated epitheloid tumour cells with a clear to pale eosinophilic cytoplasm, arranged around numerous ...
5
Granular Cell Ameloblastoma: an Unusual Histological Subtype Report and Review of Literature
... apoptotic cell death of the lesional cells and the phagocytosis by neighbouring neoplastic cells ...granular cell ameloblastomas includes other oral lesions with a similar morphology of granular cell ...
8
Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer
... Nuclear fractionation. Cells were rinsed in cold PBS and chilled on ice and harvested in the minimum volume of cold buffer I (0.32 M sucrose, 10 mM Tris-HCl pH 8.0, 3 mM calcium chloride, 2 mM magnesium acetate, 0.1 mM ...
10
Solitary Neurogenic Sarcoma of the Nose
... Conclusion This case describes an exceedingly rare tumour, which can only be diagnosed as a malignant 'spindle cell' tumour on light microscopy and which required electron microscopic ex[r] ...
11
Heat Shocking of Murine Malignant Mesothelioma Cells Enhances Their Effectiveness as an Autologous Anti Tumour Vaccine
... heat-shocked cell lysates on days 0, 7 and 14 (1 × 10 7 cells/dose) prior to subcutaneous challenge with viable AE17sOVA tumour cells on day ...delayed tumour growth relative to saline and untreated ...
10