Type I Collagen C-telopeptide
Low bone turnover in premenopausal women with type 2 diabetes mellitus as an early process of diabetes-associated bone alterations: a cross-sectional study
... procollagen type I intact N-terminal (P1NP) and serum C-terminal cross-linking telopeptide of type I collagen (CTX) as markers of bone formation and resorption, ...
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Safety, tolerability and efficacy of intra articular Progenza in knee osteoarthritis: a randomized double blind placebo controlled single ascending dose study
... CTX-I: C-terminal telopeptide of type I col- lagen; CTX-II: C-terminal telopeptide of type II collagen; CVs: coefficients of variation; ECG: ...
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Effect of Phase I Therapy on Salivary Carboxyterminal Telopetide of Type I Collagen in Chronic Periodontitis Patients
... osteoprotegerin, C-terminal pyridinoline crosslinks of type I collagen (ICTP) and β – C terminal type I collagen telopeptide ...
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The role of enteric hormone GLP-2 in the response of bone markers to a mixed meal in postmenopausal women with type 2 diabetes mellitus
... Background: Type 2 diabetes mellitus (T2D) is a complex disease associated with several chronic complications, including bone fragility and high fracture risk due to mechanisms not yet fully ...marker ...
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The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
... CITP: C-terminal telopeptide of type I collagen CMR cardiovascular magnetic resonance imaging; CV: cardiovascular; CVA: cardiovascular accident; DD: diastolic dysfunction; LGE: late ...
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Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD
... 1 C-terminal peptide (PICP) and collagen type 1 C-terminal telopeptide (ICTP), two major by-products in the synthesis and degradation of collagen, was shown to be positively ...
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Serum concentrations of carboxyl terminal propeptide of type I procollagen, amino terminal propeptide of type III procollagen, cross linked carboxl terminal telopeptide of type I collagen, and their interrelationships in schoolchildren
... The geometric means of each marker by sex and age are displayed in Figs. 1–3, c. PICP, ICTP, and P3NP all showed a significant variation with age for both sexes (ANOVA, P # 0.0015). For PICP in boys, however, post ...
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POSTPRANDIAL RESPONSES OF SERUM CALCIUM, PARATHYROID HORMONE AND C TELOPEPTIDE OF TYPE I COLLAGEN TO THREE DOSES OF CALCIUM DELIVERED IN MILK
... Acute doses of Ca rapidly increase serum Ca and reduce bone resorption concomitant with a reduction in serum parathyroid hormone (PTH) levels. The physiological response to a dose of Ca in milk and to a Ca salt may be ...
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Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]
... Type I collagen comprises more than 90% of the organic bone ...contain type I colla- gen – for example, skin, tendon, and cornea – but bone has a much higher proportion and a much ...
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Impact of low dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two year randomized study
... procollagen type I N-terminal propeptide (P1NP), a marker of bone formation, and the C-telopeptide crosslaps of type I collagen (CTX-1) and C-terminal ...
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Biochemical markers of ongoing joint damage in rheumatoid arthritis current and future applications, limitations and opportunities
... and collagen type I and ...of type I procollagen), PICP (carboxyl terminus propeptide of type I procollagen), PIINP (amino terminus propeptide of type II ...
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THE THERAPEUTIC POTENTIAL OF FRESH GOAT’s MILK AGAINST PREMATURE OSTEOPOROSIS BY INHIBITING OF BIOMARKERS OF BONE RESORPTION IN UNTRAINED HEALTHY WOMEN
... are C-terminal propeptide of type-I procollagen (PICP), the bone alkaline phosphatase (BSAP), and osteocalcin (OC), the N- terminal propeptide ...the C-terminal telopeptide (CTX), the ...
5
Mauntel_unc_0153D_16326.pdf
... concentrations of collagen byproducts in the serum as the food is broken down and digested, which may be incorrectly identified as bone resorption byproducts, such as CTx-1. 63 PINP does not appear to be ...
174
Hormone Therapy Reduces Bone Resorption but not Bone Formation in Postmenopausal Athletes
... of type I collagen were measured in hydrolyzed urine samples by high performance liquid chromatography, correc- ted for urine creatinine and expressed as nmol/ mmol Cr ...
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Antiresorptive effect of a cathepsin K inhibitor ONO 5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis
... ONO-5334 100 mg QD was added for evaluation of the dose response. ONO-5334 50 mg BID was chosen to com- pare the efficacy and safety of two regimens with a 100 mg total daily dose, to assess the potential for development ...
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Review Article Serum cross-linked N-telopeptide of type I collagen as a biomarker of bone metastases for patients with lung cancer: a meta-analysis
... of type I collagen as a biomarker of bone metastases for patients with lung cancer, were electronically searched in databases of Pubmed, Embase, and CNKI by two reviewers (Yanjun Su and Hui Chen), ...
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Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor
... Idiopathic interstitial pneumonias are a diverse group of diseases characterized by fibrosis and inflammation, of which idiopathic pulmonary fibrosis (IPF) is the most common type. The etiology of the disease is ...
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Urinary Excretion of Cross-Linked N-Telopeptides of Type 1 Collagen to Assess Bone Resorption in Infants From Birth to 1 Year of Age
... H uman bone is continuously remodeled through a coupled process of bone resorp- tion by osteoclasts followed by bone forma- tion by osteoblasts. This process is necessary for nor- mal development and bone growth as well ...
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Impact of severity, duration, and etiology of hyperthyroidism on bone turnover markers and bone mineral density in men
... terminal telopeptide of type l collagen also, urinary deoxypyridinoline cross-links (DXP), urinary DXP/urinary creatinine ratio and urinary calcium/urinary creatinine ratio were significantly higher ...
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New diagnostic modalities and emerging treatments for neonatal bone disease
... As yet, no intervention has emerged that alters the material quality of bone; one potential approach to this issue would be the removal of mutant protein prior to its export from the cell, a process called autophagy. ...
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