Tyrosinase Inhibition
An Extreme Vertices Mixture Design Approach to Optimization of Tyrosinase Inhibition Effects
... the tyrosinase inhibition effects of three mixtures included Emblica extract, L-Ascorbic acid, and Kojic ...acid. Tyrosinase is a copper-containing oxidase, which has activity for both catechol and ...
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Tyrosinase inhibition and antioxidant properties of Asphodelus microcarpus extracts
... intracellular tyrosinase activity was also confirmed by tyrosinase ...acid). Tyrosinase activity in non-treated cells was very low while α-MSH-stimulated cells showed dark band with higher ...of ...
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Antibacterial, antioxidant and tyrosinase inhibition activities of pomegranate fruit peel methanolic extract
... and tyrosinase-inhibition activities of extracts from peels, using in vitro assays, of seven com- mercially pomegranate cultivars grown in the Western Cape, South ...
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SCREENING BIOACTIVES FROM VEGETAL SOURCES AS POTENTIAL SKIN LIGHTENING AGENTS USING AN ENZYMATIC MODEL OF TYROSINASE INHIBITION, CORRELATIONS AMONGST ACTIVITY,
... in tyrosinase inhibition there is not a clear correlation with the content of phenolics, so we think that cytotoxicity could be determined by the quality of the extracted compounds rather than the quantity; ...
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Mutagenicity, antimutagenicity and tyrosinase inhibition activity of hydroglycol extracts from Terminalia chebula Retzius, Terminalia bellerica Roxb and Rafflesia kerrii Meijer
... % inhibition of mutagenesis using the formula 100-[(A-C/B-D) x100], where A is the number of revertant colonies induced by the mutagen plus the extract, B is the number of revertant colonies induced by the ...
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Anti aging and tyrosinase inhibition effects of Cassia fistula flower butanolic extract
... examples of the beneficial effects are that skin aging and skin inflammation can be reduced. C. fistula (golden shower), family Fabaceae, is found in numerous Asian countries such as Thailand, China, Myanmar and India. ...
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TYROSINASE INHIBITION, 2,2 DIPHENYL 1 PICRYLHYDRAZYL RADICAL SCAVENGING ACTIVITY, AND PHYTOCHEMICAL SCREENING OF FRACTIONS AND ETHANOL EXTRACT FROM LEAVES AND STEM BARK OF MATOA (POMETIA PINNATA)
... Tyrosinase inhibitors such as mercury, hydroquinone, and kojic acid have been widely used as skin whitening or hyperpigmentation- preventing materials, but the study results have revealed that these compounds are ...
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Evaluation of biological activities of extracts from the fruiting body of Pleurotus citrinopileatus for skin cosmetics
... poor tyrosinase inhibitory activity compared with kojic acid (a positive control) for substrates (l-DOPA and l-tyrosine) at a concentration of 100 ...showed tyrosinase inhibition at ...100.0% ...
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Screening of Indonesian plants for tyrosinase inhibitory activity
... mushroom tyrosinase inhibition of several plant extracts ...poor tyrosinase inhibitory activity (less than 50% ...showed tyrosinase inhibitory activity at more than ...
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Chemical constituents and bioactivities of garcinia griffithii T. Anderson
... Chemical and bioactivity investigations were carried out on the leaves and stem barks of Garcinia griffithii T. Anderson from Guttiferae family. Sample for each part of the plant was extracted consecutively with ...
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Isolation, Identification and Tyrosinase Inhibitory Activities of the Extractives from Allamanda cathartica
... The tyrosinase inhibitory activity of glabridin is shown in Figure 4 for L-tyrosine as substrate and Figure 5 for L-DOPA as ...of tyrosinase inhibition at concentration ...28% inhibition at ...
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Journal of Applied Pharmaceutical Science
... Tyrosinase inhibition assay (EC1.14.18.1) was performed by using the dopachrome method with L-DOPA as substrate with slight modifications (Liu et al., 2009). Briefly, the extracts/compounds and kojic acid ...
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Thiopurine Drugs Repositioned as Tyrosinase Inhibitors
... tyrosinase inhibition. B16F10 cell lysates were used to evaluate inhibition against different concentrations of mammalian tyrosinase ...
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Tyrosinase inhibitory potential of phytochemicals and mycomolecules
... minimum tyrosinase inhibitory activity of ...maximum tyrosinase inhibition of 53.3%. The tyrosinase inhibitory activity of mycomolecules was found to be positively correlated with their ...
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Inhibitory kinetics of enterolactone on mushroom tyrosinase
... mushroom tyrosinase inhibition activities were determined according to the method described in the literature with some ...mushroom tyrosinase (1250 units/mL) and ...
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Inhibition of melanogenesis by Gaillardia aristata flower extract
... B16F10 cells were seeded at a density of 5 × 10 4 cells per well in 6-well culture plates and incubated for 24 h. They were first treated with GAE for 2 h and then stim- ulated with 50 nM α-MSH for an additional 72 h. ...
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Structural Basis and Mechanism of the inhibition of the type-3 copper protein Tyrosinase from Streptomyces Antiobioticus by halide Ions
... halide inhibition is mainly limited to the observations that the inhibition is strongly pH-dependent and that the order of inhibition strength of F ⫺ , Cl ⫺ , Br ⫺ , and I ⫺ appears to be dependent ...
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The functional property of royal jelly 10 hydroxy 2 decenoic acid as a melanogenesis inhibitor
... tyrosinase-related protein 1 and 2 (TRP-1 and TRP-2) and microphthalmia-associated transcription factor (MITF) [28, 29]. Tyrosinase is a rate-limiting enzyme for controlling the synthesis of melanin. The ...
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Traditional herbal prescription LASAP C inhibits melanin synthesis in B16F10 melanoma cells and zebrafish
... μg/mL. Tyrosinase is a rate-limiting enzyme in melanin syn- ...by tyrosinase in the presence of dopa as a cofactor [23]. Tyrosinase ac- tivity of cell lysates treated with various concentrations (10, ...
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IMMUNOGENETIC STUDIES OF TYROSINASE SPECIFICITY
... At the inception of this investigation three plausible mechanisms were suggested to explain the changed enzymatic activity : ( a ) gene changes affected the bioch[r] ...
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