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Unfractionated Heparin

Effects of four commercially available factor Xa proteins on the fluorogenic anti factor Xa assay when monitoring unfractionated heparin

Effects of four commercially available factor Xa proteins on the fluorogenic anti factor Xa assay when monitoring unfractionated heparin

... Four commercially available Factor Xa (FXa) reagents were evaluated in a fluorogenic anti-FXa assay. The four reagents - of which three were of human origin and the fourth was bovine - were compared in terms of the ...

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Use of a fixed, body weight-unadjusted loading dose of unfractionated heparin for extracorporeal cardiopulmonary resuscitation

Use of a fixed, body weight-unadjusted loading dose of unfractionated heparin for extracorporeal cardiopulmonary resuscitation

... as unfractionated heparin are frequently ...of unfractionated heparin given as a bolus injection and a target activated coagulation time (ACT) of ...

5

Rates of clinically apparent heparin-induced thrombocytopenia for unfractionated heparin vs. low molecular weight heparin in non-surgical patients are low and similar

Rates of clinically apparent heparin-induced thrombocytopenia for unfractionated heparin vs. low molecular weight heparin in non-surgical patients are low and similar

... of heparin therapy because of its association with arterial and venous thrombosis ...for unfractionated heparin has generated interest in comparing the relative rates of HIT between the two classes ...

5

Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

... Background: Unfractionated heparin (UFH) is widely used as a reversible anti-coagulant in cardiopulmonary bypass (CPB). However, the pharmacokinetic characteristics of UFH in CPB surgeries remain unknown ...

11

Epidural Hematoma after the Use of Subcutaneous Unfractionated Heparin and History of Epidural Tumor

Epidural Hematoma after the Use of Subcutaneous Unfractionated Heparin and History of Epidural Tumor

... A spinal hematoma is a collection of blood that occurs between the dura mater and the spine. Hemorrhage into the spinal canal most commonly occurs in the epidural space because of the prominent epidural venous plexus. It ...

5

Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome – a retrospective propensity matched cohort study

Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome – a retrospective propensity matched cohort study

... effects, unfractionated hep- arin has been shown to have a wide range of anti- inflammatory and immunomodulatory effects ...of heparin was found to limit lung injury in endotoxemic swine [23] and mice [24] ...

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Original Article Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase

Original Article Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase

... a heparin sulfate-specific glucuronidase, mediates the onset of organ injury during early ...sepsis. Heparin has the function to attenuate inflammation and injury induced by multiple factors; however, ...

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Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti FXa assays

Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti FXa assays

... Accepted Manuscript Title: Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays Authors: Vanessa Castro-López, Leanne F[r] ...

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Assessment of the Adminstration of Low Molecular Weight Heparin for Hemodialysis Anticoagulation in Comparison to Standard Unfractionated Heparin

Assessment of the Adminstration of Low Molecular Weight Heparin for Hemodialysis Anticoagulation in Comparison to Standard Unfractionated Heparin

... fractionated heparin, are effective as unfractionated heparin (UFH), commonly used for the prevention and treatment of many thromboembolic diseases ...of heparin-induced thrombocytopenia and ...

8

The economic impact of enoxaparin versus unfractionated heparin for prevention of venous thromboembolism in acute ischemic stroke patients

The economic impact of enoxaparin versus unfractionated heparin for prevention of venous thromboembolism in acute ischemic stroke patients

... low-dose unfractionated heparin or a low-molecular-weight ...and unfractionated heparin), sug- gest that the low-molecular-weight heparin, enoxaparin, is preferable to ...

9

Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury

Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury

... Unfractionated heparin (UFH), a widely used anticoagu- lant drug, participates in the regulation of multifarious bio- logical functions [12]. We previously demonstrated that LPS induced remodeling of the ...

15

Unfractionated Heparin Therapy in Infants and Children

Unfractionated Heparin Therapy in Infants and Children

... Unfractionated heparin is frequently used in tertiary pediatric centers for the pro- phylaxis and treatment of thromboembolic ...of unfractionated heparin therapy in children are poor, as ...

11

The use of activated partial thromboplastin time versus antifactor Xa assay in monitoring continuous unfractionated heparin infusion therapy in obstetric intensive care unit

The use of activated partial thromboplastin time versus antifactor Xa assay in monitoring continuous unfractionated heparin infusion therapy in obstetric intensive care unit

... Unfractionated heparin (UFH) is an acceptable alter- native to low-molecular weight heparin (LMWH) and less expensive (Bauer 2016; Casele 2006). It may be more appropriate during stages of the ...

6

Temporality of heparin-induced antibodies: a retrospective study in outpatients undergoing hemodialysis on unfractionated heparin

Temporality of heparin-induced antibodies: a retrospective study in outpatients undergoing hemodialysis on unfractionated heparin

... This was a retrospective study done using a subpopula- tion of the outpatient hemodialysis clinic at the Univer- sity of Florida during the 6-year period from January 1, 2012 to December 31, 2017. This clinic is part of ...

9

Unfractionated heparin and enoxaparin reduce high stretch ventilation augmented lung injury: a prospective, controlled animal experiment

Unfractionated heparin and enoxaparin reduce high stretch ventilation augmented lung injury: a prospective, controlled animal experiment

... Heart, Lung and Blood Institute working group on acute lung injury identified examination of the biology of stress-induced injury to the lung in health and disease as a fertile area of future research, because ...

12

Outcomes of thromboprophylaxis with enoxaparin vs. unfractionated heparin in medical inpatients

Outcomes of thromboprophylaxis with enoxaparin vs. unfractionated heparin in medical inpatients

... or (2) receipt of a therapeutic dosage of either enoxaparin (i.e., >100 mg/day) or heparin (>25,000 IU/day) at any time after the first two inpatient days. A diagnosis of PE was identified by ICD-9-CM code ...

9

Safety of low-molecular-weight heparin compared to unfractionated heparin in hemodialysis: a systematic review and meta-analysis

Safety of low-molecular-weight heparin compared to unfractionated heparin in hemodialysis: a systematic review and meta-analysis

... Based on the analysis with the Cochrane risk of bias tool for randomized studies (Fig. 2), we observed a high rate of potential performance bias mainly caused by a lack of blinding and only few measures to ensure similar ...

12

Bivalirudin versus unfractionated heparin: a meta-analysis of patients receiving percutaneous coronary intervention for acute coronary syndromes

Bivalirudin versus unfractionated heparin: a meta-analysis of patients receiving percutaneous coronary intervention for acute coronary syndromes

... Hirulog, heparin, anticoagulation, primary percutaneous coron- ary intervention, percutaneous coronary intervention, coronary intervention, coronary angioplasty, stent, acute coronary syndrome, myocardial ...

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INCIDENCE OF HEPARIN INDUCED THROMBOCYTOPENIA IN A TERTIARY HOSPITAL

INCIDENCE OF HEPARIN INDUCED THROMBOCYTOPENIA IN A TERTIARY HOSPITAL

... of heparin induced thrombocytopenia(HIT) after treatment with unfractionated heparin and low molecular weight heparin when used prophylactically or therapeutically is largely unknown from ...

11

Platelet Function during Platelet-Rich Plasma
Sequestration in Complex Cardiac Surgical
Procedures - Prospective Controlled Study

Platelet Function during Platelet-Rich Plasma Sequestration in Complex Cardiac Surgical Procedures - Prospective Controlled Study

... Patients were enrolled after their written informed consent and local ethics committee approval were obtained. The study comprised patients scheduled for elective cardiac surgery with an estimated CPB time of more than ...

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