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Interferon Kappa Is Up-Regulated in Psoriasis and It Up-Regulates Psoriasis-Associated Cytokines in vivo

<p>Interferon Kappa Is Up-Regulated in Psoriasis and It Up-Regulates Psoriasis-Associated Cytokines in vivo</p>

... be up-regulated signi fi cantly by type II IFN- γ , suggesting in fi ltrated T help 1 cells are another possible trigger for increased IFN- κ in psoriasis ...cantly up-regulated by the same set ...

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Original Article FRZB up-regulated in hepatocellular carcinoma bone metastasis

Original Article FRZB up-regulated in hepatocellular carcinoma bone metastasis

... date, few data are yet available about bone involvement in patients with HCC, and the nature and the characteristics of bone metas- tases in HCC have not been fully explored. FRZB, the first member of the sFRP family, ...

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Inflammation related genes up regulated in schizophrenia brains

Inflammation related genes up regulated in schizophrenia brains

... sistent mRNA differences across all three subgroups, as indicated by the penalized F-ratio (Table 1). This number of clones is approximately six times higher than the expected number of four false positives (as ...

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Integrin α1 subunit is up-regulated in colorectal cancer

Integrin α1 subunit is up-regulated in colorectal cancer

... Analysis of the same set of matched samples at the tran- script level revealed that the mRNA levels of the α1 integrin subunit were significantly increased (from 2 up to 30 times) in 86.2% of the 65 ...

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FAT 10, a gene up-regulated in various cancers, is cell-cycle regulated

FAT 10, a gene up-regulated in various cancers, is cell-cycle regulated

... negatively regulated by p53 [21], which is known to play an impor- tant role in cell-cycle regulation; coupled with the obser- vation of the over-expression of the FAT10 gene in the tumors of various cancers [17], ...

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HtrA1 Is Specifically Up-Regulated in Active Keloid

HtrA1 Is Specifically Up-Regulated in Active Keloid

... Western blot analysis of HtrA1 in keloid lesions and normal skin tissues.. Soluble protein 129.[r] ...

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New insights into the Saccharomyces cerevisiae fermentation switch: Dynamic transcriptional response to anaerobicity and glucose-excess

New insights into the Saccharomyces cerevisiae fermentation switch: Dynamic transcriptional response to anaerobicity and glucose-excess

... again up-regulated after 30 min (clusters 4, 5 & ...transcriptional up-regulation of the translational machinery, specifically ribosomal proteins, comple- mented an opposite transcriptional ...

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Quantitative proteomics of the tobacco pollen tube secretome identifies novel pollen tube guidance proteins important for fertilization

Quantitative proteomics of the tobacco pollen tube secretome identifies novel pollen tube guidance proteins important for fertilization

... Protein relative quantification using the Top3 algorithm up-regulated threefold or more and up-regulated in at least two SIV-PS samples and at the same time identified using three or mor[r] ...

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Bioinformatics Analysis to Reveal Potential Differentially Expressed Long Non-Coding RNAs and Genes Associated with Tumour Metastasis in Lung Adenocarcinoma

<p>Bioinformatics Analysis to Reveal Potential Differentially Expressed Long Non-Coding RNAs and Genes Associated with Tumour Metastasis in Lung Adenocarcinoma</p>

... poor survival of patients with neuroblastoma and that it may enhance neuroblastoma progression by interacting with lncRNA SNHG1. 17 Nho et al suggested that MATR3 was involved in carcinogenesis progression by regulating ...

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Swainsonine Activates Mitochondria-mediated Apoptotic Pathway in Human Lung Cancer A549 Cells and Retards the Growth of Lung Cancer Xenografts

Swainsonine Activates Mitochondria-mediated Apoptotic Pathway in Human Lung Cancer A549 Cells and Retards the Growth of Lung Cancer Xenografts

... treatment up-regulated Bax, down-regulated Bcl-2 expression, promoted Bax translocation to mitochondria, activated mitochondria-mediated apoptotic pathway, which in turn caused the release of ...

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Retinoid acid-induced microRNA-31-5p suppresses myogenic proliferation and differentiation by targeting CamkIIδ

Retinoid acid-induced microRNA-31-5p suppresses myogenic proliferation and differentiation by targeting CamkIIδ

... The knocking down of miR-31-5p was conducted by the transfection of miR-31-5p inhibitor to thoroughly assess the role of miR-31-5p in myogenic differenti- ation and CamkII δ expression. Transfection of miR-31- 5p ...

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Original Article Upregulation of ATG4A promotes osteosarcoma cell epithelial-to-mesenchymal transition through the Notch signaling pathway

Original Article Upregulation of ATG4A promotes osteosarcoma cell epithelial-to-mesenchymal transition through the Notch signaling pathway

... was up-regulated in osteosarcoma ...invasion, up-regulated the expression of E-cadherin and down-regulated the expression of vi- mentin, Notch1 and ...invasion, ...

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The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers

The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers

... is up-regulated or down-regulated in pancreatic cancer, prostate cancer, kidney cancer, breast cancer, cervical cancer, ovarian cancer and endometrial ...be up-regulated in the early ...

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Original Article miR-22-3p suppresses cell proliferation by regulating SP1 in hepatocellular carcinoma

Original Article miR-22-3p suppresses cell proliferation by regulating SP1 in hepatocellular carcinoma

... an up-regulated expression in the inhibitor group compared with ...and up-regulated expression in inhibitor group (Figure ...through up-regulating SP1 and cell cycle relat- ed protein ...

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The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/&beta;-Catenin pathway

The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/&beta;-Catenin pathway

... significantly up-regulated in TMZ-resistant glioma cell lines U-251TMZ and M059JTMZ compared with the untreated U-251 and M059J cells, respectively (Figure ...

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Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

... down regulated during infection, since this category was strongly diminished in the tlr2 mutant ...the up regulated and down regulated groups, we se- lected a number of genes that were most ...

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Knockdown of lncRNA PVT1 inhibits prostate cancer progression in vitro and in vivo by the suppression of KIF23 through stimulating miR-15a-5p

Knockdown of lncRNA PVT1 inhibits prostate cancer progression in vitro and in vivo by the suppression of KIF23 through stimulating miR-15a-5p

... To address the effects of the interaction between miR-15a-5p and KIF23, 22RV1 and DU145 cells were introduced with si-KIF23 and si-KIF23 + miR-15a-5p inhibitor, respectively, si-NC and si-KIF23 + inhibitor NC as the ...

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Original Article Expression and function of PLAP-1 and caveolin-1 in periodontal tissues and cells of rat orthodontic tooth movement models

Original Article Expression and function of PLAP-1 and caveolin-1 in periodontal tissues and cells of rat orthodontic tooth movement models

... significantly up-regulated from day 3 as compared with the control (P < ...significantly up-regulated and then down-regulated with the increase in stimulation time, while the ...

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Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients

Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients

... This study reports the analysis of parasite-encoded chaperones, their interactors, pathways governed by them and implicate their role in clinical malaria. Inter- estingly, previously defined clusters highly correlate ...

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Changes in cellular microRNA expression induced by porcine circovirus type 2-encoded proteins

Changes in cellular microRNA expression induced by porcine circovirus type 2-encoded proteins

... were up-regulated by PCV2 ORF1 and ORF3, suggesting that these miRNAs are functionally ...differentially regulated by the corresponding ORF in the same ...is regulated by PCV2 ORFs at both ...

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