Urease Inhibitors
Synthesis and biological evaluation of novel pyrazole derivatives as urease inhibitors
... enzyme inhibitors can interact with enzymes and block their activity towards natural ...substrates. Urease inhibitors have recently attracted much attention as potential new anti-ulcer ...for ...
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Synthesis and dynamics studies of barbituric acid derivatives as urease inhibitors
... be the most active members of the series, and showed several fold more urease inhibition activity than the stand‑ ard compound thiourea (IC 50 = 21.2 ± 1.3 µM). Whereas, compounds 4a–b, 4d–e, 4g–h, 4j–4r, 4x, 4z, ...
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The effect of urea with urease inhibitors and urea on yield and nitrate content in potato tubers
... In summary it can be stated that the three-year monitoring was no signifi cant diff erence in the average yield of tubers between the other variants with the exception of one variant and also the nitrate content showed no ...
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Stone formation by Ureaplasma urealyticum in human urine and its prevention by urease inhibitors
... In this report, we show that urinary stones are formed in human urine inoculated with Ureaplasma urealyticutm T-960 and that urease inhibitors such as HXA and N-acylphosphotriamide preve[r] ...
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SYNTHESIS OF SOME D-GLUCOSE LINKED 1,2,3-TRIAZOLES AS UREASE INHIBITORS
... 1- The blank of reaction consist of five hundred microliters of 1.65mg/ml of free or immobilize or dispersion jack bean urease (dispersion is solution from urease at concentration 1.65 was mixed with 2mg/ml ...
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Synthesis and Characterization of Some New D-mannose Derivatives Containing 1, 2, 3-Triazole Moiety and Screening Their Action as Urease Inhibitors
... minutes. Urease catalyzed degradation of urea results in the formation of ammonia, which is determined by the Berthelot method (according to method of urea ...
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Molecular docking, synthesis, kinetics study, structure–activity relationship and ADMET analysis of morin analogous as Helicobacter pylori urease inhibitors
... In-silico studies were done to study the interaction pattern of newly designed ligands in the catalytic cav- ity of jack bean urease enzyme. X-ray crystal structure of Jack Bean Urease enzyme having ...
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Gossypol: New class of urease inhibitors, molecular docking and inhibition assay
... bean urease based on the X-ray structure (PDB ID: 3LA4, entry 3LA4 in the Protein Data Bank) [27, 28]: all H-O-H residues were removed, all hydrogens were added, Gasteiger charges were calculated and nonpolar ...
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Characterization of urease from Campylobacter pylori
... The enzyme appears to be unique with respect to size, electrophoretic mobility, isoelectric point, and sensitivity to urease inhibitors when compared with the ureases of Proteus, Provide[r] ...
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Original Article Inhibitory effect of plumbagin on Helicobacter pylori growth and urease activity
... because urease activity is necessary to overcome the hostile environment of the gas- tric ...Thus, urease inhibitors have the potential to be used as a supportive agent for the prevention of ...
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The role of inhibitors in mitigating nitrogen losses from cattle urine and nitrogen fertiliser inputs in pastures : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (Ph D ) in Soil Science at Massey University, Palmerston North, New Zealand
... transformation inhibitors is one of the approaches that is gaining fast momentum as a mitigation option to reduce N losses and to control N dynamics in ...transformation inhibitors can be grouped into two ...
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Nitrogen handling in the elasmobranch gut: a role for microbial urease
... measured urease activity and measured ammonia accumulation amongst gut sac preparations was probably because both ammonia production (by urease) and ammonia absorption were occurring, and that the relative ...
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Association of Helicobacter pylori in nasal polyposis
... Nasal polyp has multifactoral origin and the recent limited research have shown H. pylori in nasal polyp which might change the modality of treatment. The diagnostic profiles to detect H. pylori in nasal polyp is by ...
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Rapid urease test (RUT) for evaluation of urease activity in oral bacteria in vitro and in supragingival dental plaque ex vivo
... [8]. Urease activity in the plaque in situ has been measured indirectly by quantifying the amount of ammonia formed using Nessler’s reagent ...the urease activity indirectly, however it is not suit- able as ...
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Rapid urea broth test for yeasts
... A rapid, miniaturized, urea broth test useful for detecting urease activity of yeasts was compared to Christensen urea agar.. All urease-producing yeasts tested were positive on both med[r] ...
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Study of Helicobacter pylori in Type 2 diabetes mellitus patients with dyspepsia.
... However few other studies have shown a negative association of helicobacter pylori in Type 2 diabetics. In a study conducted in china, 63 type 2 diabetics were studied of which 29 had upper gastrointestinal symptoms. The ...
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Soil Urease Activity of Sundarban Mangrove Ecosystem, India
... soil urease activity may escape from the soil because of volatile nature of ammonia [20] ...soil urease regarding Nitrogen mineralization, urease activities in soils have established a lot of ...
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Distribution of the Urease Gene Cluster among and Urease Activities of Enterohemorrhagic Escherichia coli O157 Isolates from Humans
... of urease-encoding genes among EHEC O157 strains, we demonstrate in this study that EHEC O157:H7 and SF O157:NM differ remarkably from each other by the presence of the ure gene ...
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A Thermodynamic Study of the Interaction between Urease and Copper Ions
... in urease [43-44]. Notwithstanding heavy metal ion binding to urease is important, there is not a comprehensive binding study in this ...bean urease, which all thermodynamic parameters for the ...
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Dehydrogenases, urease and phosphatases activities of soil contaminated with fungicides
... Spring barley was harvested at the flowering stage. Soil samples were collected four times, at 14-day intervals (14, 28, 42 and 56 days) af- ter seed sowing, to determine the activity of soil enzymes: dehydrogenases ...
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