Ursodeoxycholic Acid
Combined use of ursodeoxycholic acid and bosentan prevents liver toxicity caused by endothelin receptor antagonist bosentan monotherapy: two case reports
... Although ursodeoxycholic acid can be efficacious against liver injury in clinical practice, there are no published re- ports of its usefulness in combating bosentan-induced liver ...when ...
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EFFECTS OF CURCUMIN, RESVERATROL AND URSODEOXYCHOLIC ACID ON ETHINYLESTRADIOL AND CHLORPROMAZINE- INDUCED INTRAHEPATIC CHOLESTASIS IN RATS
... The present study was designed to examine the hepatoprotective effects of curcumin (CMN), resveratrol (RSV) and ursodeoxycholic acid (UDCA) against ethinylestradiol and chlorpromazine -induced intrahepatic ...
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DEVELOPMENT AND VALIDATION OF RP-LC-UV METHOD FOR DETERMINATION OF URSODEOXYCHOLIC ACID IN DRUG SUBSTANCE AND DRUG PRODUCT
... The present work is undertaken with an aim to develop and validate an accurate, precise and rapid method for the estimation of Ursodeoxycholic Acid in tablet and bulk form. The method is simple, accurate ...
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Relatively high risk for hepatocellular carcinoma in patients with primary biliary cirrhosis not responding to ursodeoxycholic acid
... with ursodeoxycholic acid survival seems to be comparable with the general population and causes of death are mainly nonliver related ...with ursodeoxycholic acid (UDCA) ...
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Therapeutic Effects of Ursodeoxycholic Acid in Neonatal Indirect Hyperbilirubinemia: A Randomized Double-blind Clinical Trial
... and ursodeoxycholic acid (UDCA) can improve bile flow and help reducing bilirubin ...bile acid that is prescribed for treatment of various cholestatic ...bile acid in black bear’s bile, which ...
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Combination therapy of ursodeoxycholic acid and budesonide for PBC–AIH overlap syndrome: a meta-analysis
... Because there have been few mechanized large-scale randomized double-blinded controlled clinical trials or prospective controlled studies of PBC–AIH, progress in the treatment of this disease has been relatively slow. ...
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Effect of Ursodeoxycholic Acid on Liver Function in Children After Successful Surgery for Biliary Atresia
... RESULTS. Ursodeoxycholic acid treatment was resumed in 13 ...after ursodeoxycholic acid therapy was discontinued but abated after resumption of ...when ursodeoxycholic acid was ...
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Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells
... bile acid ursodeoxycholic acid (UCDA) is currently used in treatment of cholestatic liver diseases and is the treatment of choice in PBC; however, a subset of PBC patients respond poorly to UDCA ...
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DEVELOPMENT AND VALIDATION OF RP-LC-UV METHOD FOR DETERMINATION OF URSODEOXYCHOLIC ACID IN DRUG SUBSTANCE AND DRUG PRODUCT
... The present work is undertaken with an aim to develop and validate an accurate, precise and rapid method for the estimation of Ursodeoxycholic Acid in tablet and bulk form. The method is simple, accurate ...
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Original Article Treatment of intrahepatic cholestasis of pregnancy using ursodeoxycholic acid: a meta-analysis
... “ursodeoxycholic acid (or UDCA)” and “intrahepatic cholestasis of pregnancy (or ICP)” as keywords, both English and Chinese data- bases including PubMed, Cochrane Library, MEDLINE, OVID, CNKI, Wanfang ...
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Separation of ursodeoxycholic acid by silylation crystallization
... Ursodeoxycholic acid was purified by silylation crystallization in this study. By optimizing process conditions, recovery and purity of ursodeoxycholic acid was up to 99.8% and 99.5%, ...
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DEVELOPMENT AND VALIDATION OF RP HPLC METHOD TO DETERMINE URSODEOXYCHOLIC ACID IN PHARMACEUTICAL DOSAGE FORMS
... 15. Ventura CA, Tirendi S, Puglisi G, Bousquet E, Panza L Improvement of water solubility and dissolution rate of ursodeoxycholic acid and chenodeoxycholic acid by complexation with natural and ...
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Intrahepatic cholestasis of pregnancy: observational study of the treatment with low-dose ursodeoxycholic acid
... The treatment of ICP has mainly been symptomatic be- cause the pathophysiology is still unresolved. Phenobarbital, cholestyramine, S-Adenosyl-L-methionine, dexamethasone and ursodeoxycholic acid have been ...
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<p>Reductive effect of ursodeoxycholic acid on bilirubin levels in neonates on phototherapy</p>
... The mainstay of treatment in Nigeria is hospital-based phototherapy and in severe cases exchange blood transfusion, since the option of home-based photo- therapy is not available. 5,6 This has both huge economic and ...
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Impact of ursodeoxycholic acid on circulating lipid concentrations: a systematic review and meta-analysis of randomized placebo-controlled trials
... of ursodeoxycholic acid on lipid profile, PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases were searched using the following search terms within titles and abstracts (also in combin- ...
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A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
... salt ursodeoxycholic acid (UDCA) pro- tects against the membrane-damaging effects associated with hydrophobic bile ...deoxycholic acid (DCA), as well as from ethanol, TGF- b 1, Fas ligand, and ...
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Ursodeoxycholic acid counteracts celecoxib in reduction of duodenal polyps in patients with familial adenomatous polyposis: a multicentre, randomized controlled trial
... Background: Due to prophylactic colectomy, mortality in patients with familial adenomatous polyposis (FAP) has changed, with duodenal cancer currently being the main cause of death. Although celecoxib reduces duodenal ...
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Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis
... Relevant studies were searched and selected by searching the PubMed, the Cochrane Library, Embase, and CINAHL databases, as well as the Science Citation Index (updated to September 2013) using the search terms ...
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Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial)
... Background: The number of bariatric interventions for morbid obesity is increasing worldwide. Rapid weight loss is a major risk factor for gallstone development. Approximately 11 % of patients who underwent Roux-en-Y ...
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A comparative study of the treatment outcomes in Alcoholic Liver Disease patients treated with Ursodeoxycholic acid and Methionine along with Abstinence (Placebo)
... of ursodeoxycholic acid (300mg),methionine (400mg)and abstinence in the treatment of alcoholic liver disease and the objective is to achieve the following end points(primary end point -change from baseline ...
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