β catenin signaling
Original Article MicroRNA-374a promotes osteogenic differentiation of periodontal ligament stem cells through directly targeting APC/Wnt/β-catenin signaling pathway
... Wnt/β-catenin signaling pathway were investigated by TOP/FOP flash luciferase assays and Western ...Wnt/β-catenin signaling, was the target gene of ...Wnt/β- catenin ...
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Original Article PFTK1 promotes the progression of non-small cell lung cancer (NSCLC) through the Wnt/β-catenin signaling pathway
... Abstract: PFTK1, as a Cdc-related serine/threonine protein kinase, is a crucial regulator of cyclins and cell cycle. However, the role of PFTK1 in non-small cell lung cancer (NSCLC) remains elusive. In the present study, ...
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Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2
... key signaling pathways, which in turn modulate cancer progression and metastasis [7, ...Wnt signaling pathway, extensively conserved in the animal kingdom, is essential for embry- onic development and adult ...
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Original Article Shikonin inhibits proliferation and invasion of glioma cells through Wnt/β-catenin signaling pathways
... of β-catenin and downstream c-Myc genes and proteins in shikonin 5 μmol/L and 20 μmol/L groups were significantly re- duced, suggesting that shikonin represses the core components of ...
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β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation
... in β-catenin signaling impact thyroid cancer formation and ...tumors), β-catenin is stabilized specifically through phosphorylation at Ser552 and this event protects cells from ...
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Neurokinin-1 receptor is a novel positive regulator of Wnt/ β-catenin signaling in melanogenesis
... Wnt/β-catenin signaling by the inhibiting the Wnt inhibitor gene DKK1, suggesting that DKK1 is a critical factor for pigmentation inhibition of ...
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Original Article TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway
... in β-catenin protein levels (Figure ...Wnt/β-catenin signaling and related to cell growth ...Wnt/β-catenin signaling was responsible for TRAF4-induced ...
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Original Article Highly expressed DDX10 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling
... Wnt/β-catenin signaling. We then find that the activity of Wnt/β-catenin signaling is positively correlated with the level change of ...nucleus β-catenin, which ...
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Original Article Wnt/β-catenin signaling regulates pathogenesis of human middle ear cholesteatoma
... of β-catenin efficiently increased in middle ear cholesteato- ma cells when compared with normal epithelial ...and β-catenin expression, as well as the expression levels of CK16, CK18, Ki67 ...
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Simplet dependent regulation of β catenin signaling influences skeletal patterning downstream of Cx43
... that β -catenin signaling is reduced when either Cx43 or Smp function is ...influences β -catenin activity through regulation of smp expression in the skeletal precursor cells ...the ...
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Wnt/β catenin signaling modulates corneal epithelium stratification via inhibition of Bmp4 during mouse development
... Wnt/ β -catenin signaling plays a crucial role in controlling cell fate, differentiation, proliferation and apoptosis during development (Nüsslein-Volhard and Wieschaus, 1980), stem cell maintenance ...
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The role of the Wnt/β-catenin signaling pathway in the proliferation of gold nanoparticle-treated human periodontal ligament stem cells
... Wnt/β-catenin signaling is crucial for regulating em- bryonic development and cell proliferation as well as for the determination of the cell fate ...Wnt signaling, which increases nuclear and ...
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TRIM29 facilitates the epithelial-to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway
... Wnt/β-catenin signaling pathway in colorectal cancer, we used the specific Wnt/ β-catenin signaling inhibitor XAV939 to conduct stud- ies in modified RKO ...
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PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway
... major signaling pathways related to various diseases, including the Wnt/β-catenin, C/EBP, GAS, NF-κB and AP-1 pathways (Table ...Wnt/β-catenin signaling pathway when compared to ...
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CWP232228 targets liver cancer stem cells through Wnt/ β‑catenin signaling: a novel therapeutic approach for liver cancer treatment
... between β‑catenin and TCF is essential for the activation of Wnt/β‑catenin signaling ...However, β‑catenin has been traditionally considered as an ‘undruggable’ target ...
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EFEMP2 suppresses epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human bladder cancer
... Wnt/β-catenin activator LiCl were utilized to rule the Wnt/β-catenin signaling in T24 cells. As showed in MTT assay (Fig. 7A), the XAV-939 could significantly rescue the promotion of ...
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miR-96 exerts carcinogenic effect by activating AKT/GSK-3β/β-catenin signaling pathway through targeting inhibition of FOXO1 in hepatocellular carcinoma
... AKT/GSK-3β/β-catenin signaling pathway, GSK-3β acts as a key gene in phosphorylation and degradation of β-catenin ...degrade β-catenin [31, 32]. β-catenin ...
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SNHG 6 promotes the progression of Colon and Rectal adenocarcinoma via miR-101-3p and Wnt/β-catenin signaling pathway
... Wnt/β-catenin signaling pathway were down-regulated after miR-101-3p transfection ...ducer β-catenin was determined by co-transfecting β- catenin-Wt or ...
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Regulation of Wnt/β-catenin signaling by posttranslational modifications
... of β-catenin phosphorylation by GSK3: (i) Disruption of the destruction ...substrate β-catenin, thus inhibiting β-catenin phosphorylation and causing initial stabilization of ...
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Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids
... Wnt/β-catenin signaling in different developmental and homeostatic situations [11, ...of β-catenin has been reported in different tumors such as colorectal, hepatocellular, breast ...
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