β-oxidation
Lactobacillus frumenti mediates energy production via fatty acid β-oxidation in the liver of early-weaned piglets
... The gut microbiota also regulates glutathione (GSH) and amino acid metabolism in the host [39]. Our KEGG analysis shows that L. frumenti regulates amino acid metabolism and glutathione metabolism in the liver of ...
12
Fasting induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β oxidation
... increased β-oxidation in part by SIRT1-mediated deacetylation of PGC-1α ...and β-oxidation genes, but not gluconeogenic genes (model in Figure ...both β-oxidation and ...
17
Peroxisomal and Mitochondrial β-Oxidation Pathways Influence the Virulence of the Pathogenic Fungus Cryptococcus neoformans
... position of the plasma membrane due to the absence of specific fatty acids and phospholipids (42). These changes could influence trafficking of materials to the cell wall and the extracellular milieu and impair the ...
13
The Roles of β-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana
... domains (Shani et al. 1995) and is conserved in plants, yeast, and humans (Figure 6A; Zolman et al. 2001b). In S. cerevi- siae, a mutation in the equivalent Gly413 in Pxa1p (Figure 6A) impairs fatty acid ...
38
β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors
... tissues is also possible. BAIBA increases the expression of brown adipocyte-specific genes both in vitro and in vivo through a PPAR mediated mechanism. BAIBA also functions to increase hepatic fatty acid ...
33
Plasma incorporation, apparent retroconversion and β-oxidation of 13C-docosahexaenoic acid in the elderly
... Six participants in each group was required to have suffi- cient power analysis with a b = 0.8 which is defined as 80% chance to reject the null hypothesis which state that there is no relationship between the variable ...
9
Defects in Mitochondrial and Peroxisomal β-Oxidation Influence Virulence in the Maize Pathogen Ustilago maydis
... the potential contribu- tion of  -oxidation to the function of these penetration structures. The importance of -oxidation for disease development or vir- ulence elaboration in animal and human pathogens ...
12
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.
... FAO IS DISPENSABLE FOR ENERGY HOMEOSTASIS, BIOMASS SYNTHESIS AND HISTONE ACETYLATION IN QECS As cells use FAO for ATP and acetyl-CoA production Ghesquiere et al., 2014; Xiong et al., 201[r] ...
86
The Transcription Factor Homolog CTF1 Regulates β-Oxidation in Candida albicans
... ctf1 ⌬ / ⌬ strains have apparently normal peroxisomes. Our finding that CTF1 is required for  -oxidation and for maximal expression of PEX5, a critical protein import receptor, sug- gested that ctf1 ⌬ / ⌬ mutant ...
11
Peroxisomal Fatty Acid β-Oxidation Is Not Essential for Virulence of Candida albicans
... This outcome illustrates the ability of C. albicans to rapidly adapt to the hostile environment of the macrophage. The re- sponse of C. albicans to phagocytosis by macrophages has been studied by genome-wide expression ...
10
Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism
... acid oxidation occurs following ...acid β-oxidation enzymes, long-chain acyl CoA dehydrogenase (LCAD) and β-hydroxyacyl CoA dehydrogenase (βHAD), were hyperacetylated and their activities ...
18
Fed-batch production of MCL-PHA with elevated 3-hydroxynonanoate content
... the β-oxidation inhibitor and a growth rate which avoids toxic accumulation of both nonanoic and acrylic acid enhanced growth and PHA accumulation as well as controlled the monomeric ...a ...
8
Drosophila Prominin-like, a homolog of CD133, interacts with ND20 to maintain mitochondrial function
... It is interesting to note that in S2 cells, the alterations of ATP and ROS, together with the expression levels of mitochondrial proteins including VDAC, NDUFS3, ND-20, and COX IV, lasted for 2 days after the down- ...
14
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy
... upon β-oxidation of fatty acids in the liver, we analyzed the levels of a broad array of acylcarnitines in livers of WT and NCoR DADm mice under hypothyroid, euthyroid, and hyperthyroid conditions by tandem ...
12
The Antioxidant Gallic Acid Inhibits Aflatoxin Formation in Aspergillus flavus by Modulating Transcription Factors FarB and CreA
... acid β oxidation [39] and fatty acid β oxidation is a fundamental contributor to polyketide mycotoxin (aflatoxin and sterigmatocystin) formation ...peroxisomal β-oxidation genes ...
24
The ins and outs of peroxisomes: co-ordination of membrane transport and peroxisomal metabolism
... acid β-oxidation, whereas in mammals, very long chain fatty acids (VLCFA) are first chain-shortened in the peroxisome prior to complete oxidation in ...mitochondria. Oxidation of long chain ...
15
Octopus (Enterocopus dofleini) Liver Extract Displays Triglyceride-Lowering Effect in HepG2 Cells
... Liver plays a central role in the biogenesis of major metabolites such as glucose, fatty acids, and cholesterol. Excessive alcohol intake causes fatty liver under a condition characterized by large accumulation of ...
5
Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα
... decreased β-hydroxybutyrate in the culture medium and reduced expression of fatty acid oxidation–related genes (Figure 3, E–J, and Supplemen- tal Figure 6, C and ...addition, β-oxidation of 3 ...
14
Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death
... Mitochondrial trifunctional protein (MTP) is a hetero-octamer of four α and four β subunits that catalyzes the final three steps of mitochondrial long chain fatty acid β-oxidation. Human MTP defi- ...
8
Prevention of Murine Atherosclerosis with Bempedoic Acid
... and β-oxidation (sections ...acid β-oxidation. Malonyl-CoA inhibits Cpt1α and β- oxidation, and decreases in malonyl CoA relives this ...
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