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VEGF isoform expression and exon structure

PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23

PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23

... of exon 23. STAT3α is the longer isoform and encodes the full-length oncogenic STAT3 α ...STAT3 exon 23 is ...the expression of STAT3 α ...the expression of STAT3 target ...oncogenic ...

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Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury

Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury

... in isoform expression as a possible explanation for these discrepancies, we assessed mRNA as there are no isoform-specific antibodies cur- ...in VEGF isoform expres- sion occurred in ...

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Alternative splicing of TIA 1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

Alternative splicing of TIA 1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

... and VEGF-A 165 b down regu- lation in patients suggests a complex interaction, just as for alternative splicing of p73 and VEGF-A 165 b isoforms, also demonstrated in colon cancer (Diaz et ...of ...

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Exon expression profiling reveals stimulus mediated exon use in neural cells

Exon expression profiling reveals stimulus mediated exon use in neural cells

... An exon was considered partially 5' spliced or 3' spliced if it shares the same chromosome, orientation, and either the 5' end-point or the 3' end-point with some other exon, respec- ...an exon is ...

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A cryptic promoter in the first exon of the SPG4gene directs the synthesis of the 60-kDa spastin isoform

A cryptic promoter in the first exon of the SPG4gene directs the synthesis of the 60-kDa spastin isoform

... restrict expression of a toxic product ...spastin isoform is strongly unfavored in ...model, expression of an SPG4 cDNA containing the 5'-UTR abun- dantly produces the shorter protein isoform ...

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The PDZ1 and PDZ3 Domains of MAGI-1 Regulate the Eight-Exon Isoform of the Coxsackievirus and Adenovirus Receptor

The PDZ1 and PDZ3 Domains of MAGI-1 Regulate the Eight-Exon Isoform of the Coxsackievirus and Adenovirus Receptor

... Blots were also probed for ␤-actin expression to control for pro- tein loading. There was a significant reduction in total CAR Ex8 after cotransfection with MAGI-1. In contrast, there was no dif- ference in the ...

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LARP1 isoform expression in human cancer cell lines

LARP1 isoform expression in human cancer cell lines

... expressed isoform indicates it has a conserved biological function [ 29 ], the role of non-expressed isoforms remains controversial [ 9 , 30 ...that exon 1 of SI-LARP1 is highly conserved within the ...

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VEGF System in Dog’s Thymus—Temporal Expression

VEGF System in Dog’s Thymus—Temporal Expression

... The understanding of the vascular behavior, its structure and interferences that occur along the thymic angi- ogenesis and involution can help to elucidate certain conditions. Autoimmune diseases, thymic tumors ...

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Joint estimation of isoform expression and isoform-specific read distribution using multisample RNA-Seq data.

Joint estimation of isoform expression and isoform-specific read distribution using multisample RNA-Seq data.

... differential expression analysis To investigate how much power one can gain in estimating read distribution by integrating multiple samples, we perform a simu- lation study for detecting differential ...

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VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration.

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration.

... the expression of regulator of calcineurin 1 ...to VEGF-A-stimulation (Rivera et ...regulating VEGF-A mediated endothelial ...Hence, VEGF-A isoform-specific elevation in RCAN1 ...

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VEGF A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164b therapy

VEGF A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164b therapy

... inhibitory VEGF by expressing this molecule in a model of intestinal inflammation, and to evaluate its expression as a potential new therapeutic approach for treating ...b expression on colon ...by ...

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A Brassica exon array for whole transcript gene expression profiling

A Brassica exon array for whole transcript gene expression profiling

... The aim of this study was to develop a WT exon GeneChipH array for Brassica. Brassica has a complex genome structure typical of many crop plants. A series of genome duplication events leading to the diploid ...

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ELF5 isoform expression is tissue specific and significantly altered in cancer

ELF5 isoform expression is tissue specific and significantly altered in cancer

... Abstract Background: E74-like factor 5 (ELF5) is an epithelial-specific member of the E26 transforming sequence (ETS) transcription factor family and a critical regulator of cell fate in the placenta, pulmonary bronchi, ...

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Calponin Isoform Expression in the Japanese Pearl Oyster, Pinctada fucata

Calponin Isoform Expression in the Japanese Pearl Oyster, Pinctada fucata

... Protein expression analysis revealed the possibility that other isoforms were ex- pressed in ...same exon encoding the N-terminal region of the CH ...

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Structure and dynamics of single-isoform recombinant Neuronal Human Tubulin

Structure and dynamics of single-isoform recombinant Neuronal Human Tubulin

... the expression and purification of recombinant isotypically pure unmodified human tubulin competent for in vitro dynamics assays and report its dynamic parameters as well as cryo-EM structure at ...

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Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin

Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin

... to isoform differences, purification method, and/or the abundant and diverse post-translational modifications found on brain ...the expression and purification system described here will shed light on their ...

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Structure and dynamics of single isoform recombinant Neuronal Human Tubulin

Structure and dynamics of single isoform recombinant Neuronal Human Tubulin

... the expression and purification of recombinant isotypically pure unmodified human tubulin competent for in vitro dynamics assays and report its dynamic parameters as well as cryo-EM structure at ...

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Radionuclide imaging of angiogenesis. Imaging of VEGF-A expression in tumors using a radiolabeled anti-VEGF monoclonal antibody

Radionuclide imaging of angiogenesis. Imaging of VEGF-A expression in tumors using a radiolabeled anti-VEGF monoclonal antibody

... is VEGF-A, usually referred to as VEGF [2]. VEGF signals through the VEGF receptor 2 (VEGFR-2) ...by exon 4, present on all VEGF isoforms, and prevents interaction of ...

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Activation of Heterologous Gene Expression by the Large Isoform of Hepatitis Delta Antigen

Activation of Heterologous Gene Expression by the Large Isoform of Hepatitis Delta Antigen

... the structure or conformation of this ...LHDAg expression vector was cotransfected into 293 cells with 3 mg of replication-com- petent overlength HDV plasmid pDL452, which is designed to express HDV genomic ...

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Androgen-dependent alternative mRNA isoform expression in prostate cancer cells

Androgen-dependent alternative mRNA isoform expression in prostate cancer cells

... mRNA isoform switches control alternative protein isoforms and non-coding ...an isoform called ...protein isoform of TPD52 known as PrLZ (left ...PrLZ isoform in response to androgens (middle ...

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