Venezuelan equine encephalitis
Role of adhesion molecules and inflammation in Venezuelan equine encephalitis virus infected mouse brain
... Neurovirulent Venezuelan equine encephalitis virus (VEEV) is a member of the genus Alphavirus, in the family ...lethal encephalitis in equines and occasionally infect humans ...
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Testosterone correlates with Venezuelan equine encephalitis virus infection in macaques
... to Venezuelan equine encephalitis virus (VEEV) in macaques which were used as part of a larger study conducted by the Department of Defense to better characterize pathological responses to ...
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Potential Sources of the 1995 Venezuelan Equine Encephalitis Subtype IC Epidemic
... Venezuelan equine encephalitis viruses (VEEV) are single- stranded, message-sense RNA alphaviruses (Togaviridae) with a genome of approximately 11 kb (32, ...and equine disease ...
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Glycosaminoglycan Binding Properties of Natural Venezuelan Equine Encephalitis Virus Isolates
... of Venezuelan equine encephalitis (VEE) virus (VEEV) arise via mutation of progenitor enzootic strains that replicate poorly in ...of equine virulence and viremia potential, suggesting that ...
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Pseudoinfectious Venezuelan Equine Encephalitis Virus: a New Means of Alphavirus Attenuation
... Venezuelan equine encephalitis virus (VEEV) is a reemerging virus that causes a severe and often fatal disease in equids and hu- mans. In spite of a continuous public health threat, to date, no ...
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Role of Dendritic Cell Targeting in Venezuelan Equine Encephalitis Virus Pathogenesis
... Venezuelan equine encephalitis virus (VEE) is a positive- sense, single-stranded RNA Alphavirus belonging to the family ...in encephalitis, most commonly in children and the elderly ...
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Venezuelan equine encephalitis virus nonstructural protein 2 in the host cell
... employed Venezuelan equine encephalitis replicon particles (VRP), which are non-propagating viral vectors that express all four of the viral nonstructural proteins, replicate their genomic RNAs, and ...
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Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation
... encoded by three genes in the mammalian genome (8). PP1 is ubiquitously expressed throughout the cell; however, each isoform localizes differently. PP1 catalytic subunits interact with over 600 regulatory PP1-interacting ...
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Noncytopathic Replication of Venezuelan Equine Encephalitis Virus and Eastern Equine Encephalitis Virus Replicons in Mammalian Cells
... Venezuelan equine encephalitis (VEE) and eastern equine encephalitis (EEE) viruses are important, natu- rally emerging zoonotic ...and equine pathogens which still pose a serious ...
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Blood genomic profiles of exposures to Venezuelan equine encephalitis in Cynomolgus macaques (Macaca fascicularis)
... pathogen. Venezuelan equine encephalitis (VEE) is a mosquito-borne viral disease caused by an enveloped single-stranded RNA virus of the family Togaviridae, genus Alphavirus ...
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Recombinant vaccinia virus/Venezuelan equine encephalitis (VEE) virus protects mice from peripheral VEE virus challenge.
... 4697 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Mice immunized with recombinant vaccinia virus VACC expressing Venezuelan equine encephalitis VEE virus capsid prot[r] ...
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Envelope Glycoprotein Mutations Mediate Equine Amplification and Virulence of Epizootic Venezuelan Equine Encephalitis Virus
... of Venezuelan equine encephalitis (VEE) result from high-titer equine viremia of IAB and IC subtype viruses that mediate increased mosquito transmission and spillover to ...for equine ...
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Replicon Particles of Venezuelan Equine Encephalitis Virus as a Reductionist Murine Model for Encephalitis
... Venezuelan equine encephalitis virus (VEE) replicon particles (VRP) were used to model the initial phase of VEE-induced encephalitis in the mouse ...acute encephalitis with signs ...
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Ablation of Programmed −1 Ribosomal Frameshifting in Venezuelan Equine Encephalitis Virus Results in Attenuated Neuropathogenicity
... alphaviruses Venezuelan equine encephalitis virus (VEEV), eastern equine encephalitis virus (EEEV), and western equine encephalitis virus (WEEV) are arthropod-borne ...
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Development of a novel monoclonal antibody with reactivity to a wide range of Venezuelan equine encephalitis virus strains
... eral inoculation [14]. After airborne infection there is the additional possibility that virus may multiply in the olfac- tory neuroepithelium and thereby gain direct access to the olfactory nerve and brain. Thus, there ...
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A putative receptor for Venezuelan equine encephalitis virus from mosquito cells.
... On the basis of the cross-reactivity of monoclonal antibodies prepared against the C6/36 cell laminin-binding protein with similar proteins derived from vertebrate cells and the observat[r] ...
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Laboratory studies of Venezuelan equine encephalitis virus in equines, Texas, 1971
... Most 16 of 23 of the epizootic strain isolates from vaccinated equines were obtained from animals bled within 9 days of vaccination.. In these cases, infection with epizootic virus presu[r] ...
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Temperature-sensitive Steps in the Biosynthesis of Venezuelan Equine Encephalitis Virus
... It appeared that pre- I, i virus multiplication was reversibly inhibited incubation at 37 C by-passed the early tempera- at 44 C; ii no IRNA synthesis occurred; and ture-sensitive step a[r] ...
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jit609.pdf
... Genes encoding the indicated S and N proteins were synthe- sized from Bio Basic (Ontario, Canada) and packaged into Venezuelan equine encephalitis virus replicon particles (VRPs). Following ...
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Cellular and Humoral Immune Responses to Alphavirus Replicon Vaccines Expressing Cytomegalovirus pp65, IE1, and gB Proteins
... alphavirus, Venezuelan equine encephalitis virus, to produce virus-like replicon particles (VRP) expressing various combinations of pp65, IE1, or gB proteins of human ...
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