viral replication
Colocalization of Baculovirus IE-1 and Two DNA-Binding Proteins, DBP and LEF-3, to Viral Replication Factories
... during viral replication, BmNPV-infected BmN cells were examined by immunostaining and confocal microscopy with DBP ...of viral DNA replication at around 8 h ...of viral DNA ...
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Lytic viral replication and immunopathology in a cytomegalovirus induced mouse model of secondary hemophagocytic lymphohistiocytosis
... abundant viral triggers of HLH, this Arenavirus carries a (-)ssRNA genome and is known to be noncytopathic in vivo ...lytic replication cycle, mediating direct cytopathic effects in infected tissues and ...
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The Majority of Freshly Sorted Simian Immunodeficiency Virus (SIV)-Specific CD8+ T Cells Cannot Suppress Viral Replication in SIV-Infected Macrophages
... suppressed viral replication in SIV-infected macrophages in panel ...of viral replication in SIV- infected CD4 ⫹ T cells and ...of viral replication observed between CD4 ⫹ T ...
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A Complex Comprising Phosphatidylinositol 4-Kinase IIIβ, ACBD3, and Aichi Virus Proteins Enhances Phosphatidylinositol 4-Phosphate Synthesis and Is Critical for Formation of the Viral Replication Complex
... the replication of certain positive-strand RNA viruses and that the viruses utilize various strategies to generate PI4P-enriched environments at genome replication ...at viral replication ...
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The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products
... genome replication of an MCMV mutant carrying a deletion of the ie3-specific exon 5, the multifunctional IE3 protein (611 amino acids; pIE611) is considered essential for viral ...for viral ...
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Plum Pox Virus 6K1 Protein Is Required for Viral Replication and Targets the Viral Replication Complex at the Early Stage of Infection
... the replication vesicles that target the chloroplast for robust viral replication (24, ...of viral infection, 6K1 formed punctate structures ...other viral replicase elements, such as ...
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Dynamic and Nucleolin-Dependent Localization of Human Cytomegalovirus UL84 to the Periphery of Viral Replication Compartments and Nucleoli
... for viral genome replica- ...cytomegalovirus viral replication factor UL84 relative to other proteins in- volved in viral DNA synthesis and to replicating viral DNA in infected cells, ...
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Amino Acid Mutations in the NS4A Region of Hepatitis C Virus Contribute to Viral Replication and Infectious Virus Production
... establish replication-competent ...HCV replication and infectious virus pro- duction in chimeric RNA-transfected cells were observed, and several amino acid mutations in NS4A were identified in replicating ...
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HIV Exploits Antiviral Host Innate GCN2 ATF4 Signaling for Establishing Viral Replication Early in Infection
... cute viral infections trigger an antiviral host innate defense response in the infected host for restricting viral replication and dissemination ...However, viral pathogens have evolved ...
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DNA-Binding Properties of African Swine Fever Virus pA104R, a Histone-Like Protein Involved in Viral Replication and Transcription
... of viral genes (A104R, CP204L, and B646L genes) and of the reference gene (cyclophilin A gene) were quantified using the standard curves of different plasmids (pGEM- Teasy_A104R, pGEM-Teasy_CP204L, ...
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Histone deacetylase 1 interacts with HIV 1 Integrase and modulates viral replication
... To purify cellular proteins in a complex with the HIV integrase, we have developed a purification method based on the use of streptavidin magnetic beads coupled to the integrase and the viral DNA of interest. ...
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Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication
... The first tyrosine (Y) phosphorylation was identified at position 102 in the TAD of the bovine papillomavirus (BPV) E2 protein (7). By comparing wild-type (WT) E2 to phos- phodeficient and phosphomimetic mutants, we ...
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Interferons Accelerate Decay of Replication-Competent Nucleocapsids of Hepatitis B Virus
... by viral antigen-specific cytotoxic T lymphocytes and noncytolytic suppression of viral replication, which is most likely mediated by inflammatory cytokines, such as gamma interferon (IFN- ␥ ) and ...
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The replication functions of polyomavirus large tumor antigen are regulated by phosphorylation.
... Treatment with smaller quantities of CUAP stimulated the ability of the viral protein to mediate replication of constructs containing the viral replication origin, while higher concentra[r] ...
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Transmission of Human Immunodeficiency Virus Type 1 from a Patient Who Developed AIDS to an Elite Suppressor
... less replication competent than isolates from HLA-B*57 progressors ...lower replication capacity of HIV-1 isolates in LTNP and ES may be the result, rather than the cause, of suppressed evolution: a ...
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Securitizing British India: A New Framework of Analysis for the First Anglo Afghan War
... temperature. Viral replication complexes (containing predominantly genome (+) RNA products being copied from minus-strand templates) were detected with mouse anti-dsRNA antibody (1:1000; English & ...
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Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
... sense viral ligands and give a warning for viral infection by signaling ...uncoating, viral genome replication, viral protein production, their assembly and release are provoked by the ...
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Different Modes of Human Papillomavirus DNA Replication during Maintenance
... the replication of HPV DNA in such ...of replication mechanisms that are involved in the two modes of ...DNA replication licensing proteins such as ORCs and MCMs are associated with HPV16 DNA in W12 ...
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Molecular biology of the human immunodeficiency virus accessory proteins.
... Though accessory proteins are not required for viral replication, they are nonetheless capable of modulating replication events, even in vitro, and accordingly, phenotypes associated wit[r] ...
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Cyclin-Dependent Kinase Activity Is Required for Efficient Expression and Posttranslational Modification of Human Cytomegalovirus Proteins and for Production of Extracellular Particles
... prolonged replication cycles have evolved mech- anisms for short-circuiting the host cell cycle machinery very early in the infection to effect cell cycle arrest and prevent competition from cellular processes for ...
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