Virion secretion
Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model
... and virion secretion occur, genome maturation is then ar- ...immature secretion phenotype of mutant I97L (51). This study suggests that virion secretion is most likely to involve the ...
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Impairment of Hepatitis B Virus Virion Secretion by Single-Amino-Acid Substitutions in the Small Envelope Protein and Rescue by a Novel Glycosylation Site
... rescues virion secretion of the G145R mutant without altering its immune-escape phe- notype ...rescue virion secretion of the I110M mutant when it was present on a different molecule of the S ...
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Drastic Reduction in the Production of Subviral Particles Does Not Impair Hepatitis B Virus Virion Secretion
... reduced secretion of subviral parti- cles, we attempted to reduce S protein expression at the trans- lational ...protein secretion by 55 and 83%, respectively, whereas the A152T/G158C and A152C/G158C ...
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Duck Hepatitis B Virus Virion Secretion Requires a Double-Stranded DNA Genome
... were secretion competent, whereas immature nucleocapsids were intrinsically secretion ...two-step virion secretion assay, we sought to determine at what stage of reverse transcription the ...
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Impaired Virion Secretion by Hepatitis B Virus Immune Escape Mutants and Its Rescue by Wild-Type Envelope Proteins or a Second-Site Mutation
... impair virion secre- tion and are thus predicted to delay virus spread (29, ...in virion formation can be rescued by the WT virus at a 1:1 ratio, but that will most likely reverse the immune escape pheno- ...
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The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion
... HBV virion secretion in HepAD38 stable cells with established viral ...HBsAb. Virion-associated capsids and nonenveloped capsids were detected by a core ...HBV virion DNA and nonenveloped ...
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Critical Role of the 36-Nucleotide Insertion in Hepatitis B Virus Genotype G in Core Protein Expression, Genome Replication, and Virion Secretion
... creased de novo core protein translation or the 12-aa insertion slowed core protein degradation. Only genotype G constructs were examined, because the murine monoclonal antibody failed to immunoprecipitate core protein ...
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Capsid Phosphorylation State and Hepadnavirus Virion Secretion
... in virion secretion, if any, has remained ...and secretion of DNA-containing virions, as in ...in virion secretion was analyzed through mutagenesis. For secretion of empty HBV ...
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Hepatitis B Virus Genotype G: First Report of Complete Genomic Analysis from the African Continent
... At the molecular level the genomes contained 2 stop codons in the precore gene at positions 2 and 28 which prevents the synthesis of HBeAg [10,13,40]. All HBV-G isolates harbour the double A1762T transversion and G1764A ...
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Myosin Va Enhances Secretion of Herpes Simplex Virus 1 Virions and Cell Surface Expression of Viral Glycoproteins
... efficient secretion of HSV-1 in- fectivity but not for production of intracellular ...impacts virion secretion, we transfected HeLa cells with the mRED-DN-myoVa iso- forms and mRED control constructs ...
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Collective Viral Spread Mediated by Virion Aggregates Promotes the Evolution of Defective Interfering Particles
... Coinfection loss was probably not driven by reduced virion aggregation. To test whether the observed loss of cells coinfected with the two fluorescently labeled viruses was due to the emergence of virus variants ...
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Identification of virion associated transcriptional transactivator (VATT) of SGIV ICP46 promoter and their binding site on promoter
... ICP46 was firstly found to encode a very early protein of approximately 46 kDa in frog virus 3 (FV3), and have been identified as IE genes in FV3, SGIV and Bohle iri- dovirus (BIV) [11–13]. By comparative genomic ...
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Intracellular forms of simian virus 40 nucleoprotein complexes. III. Study of histone modifications.
... These results and our previous analysis of the virion assembly pathway suggest that three stages are involved in the packaging of simian virus 40 chromatin into the mature virion: i modi[r] ...
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Vaccinia Virus A6 Is Essential for Virion Membrane Biogenesis and Localization of Virion Membrane Proteins to Sites of Virion Assembly
... VACV virion morphogenesis ...in virion morphogenesis, we constructed an IPTG-inducible A6L mutant that showed more stringent repression of A6 expres- sion at normal ...
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Herpes Simplex Virus Products in Productive and Abortive Infection I. Stabilization with Formaldehyde and Preliminary Analyses by Isopycnic Centrifugation in CsCl
... The purpose of this paper is i to document the instability of the herpes virion in CsCl density gradients, ii to show that the virion can be stabilized by treatment with formaldehyde pri[r] ...
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Structural and functional studies of a 39,000-Mr immunodominant protein of vaccinia virus.
... The virion protein recognized by the monospecific antibody lane 1 was compared with the virion proteins that reacted with hyperimmune polyclonal antiserum from rabbits inoculated with di[r] ...
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POTENTIAL HERBS AGAINST DIABETES MELLITUS – AN UPDATE
... Gestational diabetes(GDM) has been defined as any degree of glucose intolerance with onset or first recognition during pregnancy, to differentiate it from pre-diagnosed type 1 or type 2 diabetes or maturity-onset ...
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Intracellular forms of simian virus 40 nucleoprotein complexes. IV. Micrococcal nuclease digestion.
... Virion assembly intermediates with different degrees of virion maturation showed intermediate resistance, and three products were found: nucleosomal DNA fragments, representing the fract[r] ...
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Uukuniemi Phlebovirus Assembly and Secretion Leave a Functional Imprint on the Virion Glycome
... the virion surface and demonstrated direct recogni- tion of the virion by DC-SIGN, consistent with C-type lectin cell attachment ...during virion assembly in the Golgi apparatus, Gc exhibited ...
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Two large virion envelope glycoproteins mediate Epstein-Barr virus binding to receptor-positive cells.
... Utilizing the purified individual virion envelope proteins reconstituted in artificial liposomes, we have investigated the role of each as it pertains to virion binding to the EB virus r[r] ...
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