Von Willebrand Factor Antigen
Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome
... Abstract In this prospective study of 45 patients, we tested the hypothesis that markedly elevated levels of plasma von Willebrand antigen vWf-Ag a marker of endothelial cell injury, mig[r] ...
8
Reliability of Plasma Von Willebrand Factor Antigen in Prediction of Esophageal Varices in Patients with Liver Cirrhosis
... Plasma Von Willebrand factor-Ag level: It was significantly higher in patients with OVs than those without varices (P value = ...and Von Willebrand factor-Ag level (rho = ...
9
Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding
... abnormalities: factor VIII co- agulant activity (FVIII: C) was 10% of normal pooled plasma, von Willebrand factor antigen (VWF Ag) was 7%, von Willebrand factor ...
6
Studies of the human factor VIII/von Willebrand factor protein III Qualitative defects in von Willebrand's disease
... The Factor VIII/von Willebrand factor protein was characterized in two unrelated patients with von Willebrand's disease in whom procoagulant and Factor VIII/von ...
15
The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study
... activated or damaged. Therefore, plasma vWF level is considered a marker of endothelial dysfunction, a condition that predisposes to atherosclerosis and thrombosis. Because of its direct role in hemostasis, and its ...
6
Procoagulatory changes induced by head-up tilt test in patients with syncope: observational study
... of von Willebrand factor (VWF:GP1bA) was analysed with an immunoassay based on an anti- body against glycoprotein 1b (GP1b) and a GP1b con- struct that binds VWF in the sample (Innovance VWF:Ac; ...
7
Limited polymorphism in Plasmodium falciparum ookinete surface antigen, von Willebrand factor A domain related protein from clinical isolates
... Methods: Clinical isolates from a wide range of geographical regions were collected. Direct sequencing of PCR products was then used to determine the extent of polymorphisms for the novel Plasmodium falciparum sexual ...
5
Carbohydrate of the Factor VIII/von Willebrand Factor in von Willebrand's Disease
... the von Willebrand's disease patients with normal FVIII/vWF carbohydrate had abnormal crossed immunoelectrophoretic patterns characterized by absence of the less anodic forms of Factor VIII-related ...
6
Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow
... of von Willebrand factor (vWF) antigen and vWF multimeric forms larger than those present in normal plasma, was the red blood cell (RBC)-suspending medium instead of serum-free medium (SFM), ...
7
Intracellular trafficking of factor VIII to von Willebrand factor storage granules
... an antigen-capture vWf ELISA using immobilized AvW-1 (or MBC ...vWf antigen levels were expressed as nanograms per milliliter, measured against serially diluted normal pool human plasma plotted as a ...
13
On the miscellaneous aspects of von Willebrand factor
... Mouse ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) does not cleave human VWF very efficiently [25], so whether pro- teolysis has an influence on ABO dependent VWF clearance ...
197
Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex
... von Willebrand antigen II (vW AgII) and von Willebrand factor (vWf) are immunochemically distinct proteins that are deficient in the plasma and platelets of patients with severe ...
8
Comorbidities associated with higher von Willebrand factor (VWF) levels may explain the age-related increase of VWF in von Willebrand disease
... F.W.G. Leebeek received research support from CSL Behring and Shire for performing the Willebrand in the Netherlands (WiN) study, and is consultant for uniQure, Novo Nordisk and Shire, of which the fees go to the ...
13
Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation
... peak thrombin parameters, which is in agreement with findings of Machlus and colleagues [3]. Allen and co-workers also observed an increase in ETP and thrombin peak with high prothrombin, while elevated FVIII resulted in ...
22
Familial clustering of factor VIII and von Willebrand factor levels
... Both factor VIII and VWF Ag levels are also influenced by blood group and age 0rstavik and coworkers (18) found that the effect of blood group and age on factor VIII level was secondaiy [r] ...
5
Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin Role of platelet activation, fibrinogen, and two distinct membrane receptors
... purified von Willebrand factor (vWF), obtained from unrelated patients affected by type IIB von Willebrand disease, were found to have normal sialic acid content (between 129 and 170 ...
9
von Willebrand factor binds to platelets and induces aggregation in platelet type but not type IIB von Willebrand disease
... Platelet-type von Willebrand disease (vWD) and pseudo-vWD are two recently described intrinsic platelet defects characterized by enhanced ristocetin-induced agglutination in platelet-rich ...a von ...
12
Genetic Variations in Exon 3 of VWF Gene in Patients with Von Willebrand Disease (VWD) from South-West Iran
... Von Willebrand disease (VWD) is an autosomally inherited bleeding disorder with the prevalence of 1% based on population ...in Von Willebrand Factor (VWF) which is a glycoprotein with ...
5
Disulfide Bonds and the Quaternary Structure of Factor VIII/von Willebrand Factor
... chromatography and 4% agarose gel filtration was subjected to sodium dodecyl sulfate gel electrophoresis on gels containing 2% acrylamide and 0.5% agarose. We find a series of multimers of which the apparent molecular ...
9
Prediabetes: Pathogenesis and Adverse Outcomes
... are von Willebrand factor (vWF), angiopoietin-2 (Ang- 2), Krebs von den Lungen-6 (KL-6), soluble receptor for advanced glycation end products (RAGE), tumor necrosis factor-alpha (TNF- ...
6