vWF, von Willebrand factor
Predictors of Bleeding from Esophageal Varices: The Role of Factor VII and von Willebrand Factor (vWF)
... and vWF (von willebrand factor) in predicting bleeding in patients with eosphogeal ...etiologic factor for their liver disease, hemoglobin was ...
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Superiority of the Rapid Von Willebrand Factor (VWF) VWF:GPIbR and VWF:GPIbM Assays in Type 2A, 2B and 2M Von Willebrand Disease
... of von Willebrand disease (VWD) by the International Society on Thrombosis and Haemostasis (ISTH) started with the discovery of Ruggeri in 1980 of heightened interaction of ristocetin induced platelet ...
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Comorbidities associated with higher von Willebrand factor (VWF) levels may explain the age-related increase of VWF in von Willebrand disease
... VWF:Ag, VWF col- lagen binding capacity (VWF:CB), VWF activity (measured by the VWF monoclonal antibody assay; VWF:Ab) and FVIII coagulant activity (FVIII:C) were centrally measured at the Erasmus ...
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Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress induced platelet aggregation
... large von Willebrand Factor (vWF) multimers were ...of vWF. Unusually large vWF multimers produced by human endothelial cells ...
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Role of serum ADAMTS13 and Von Willebrand Factor (VWF) as early Prognostic Markers in Identifying the Disease Course in Dengue Fever
... IV]), VWF was not consistently correlated with disease ...of VWF at enrollment was highest in children with dengue hemorrhagic fever (DHF), followed by those with dengue shock syndrome ...plasma VWF ...
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Immunohistochemistry comparing endoscopic vein harvesting vs. open vein harvesting on saphenous vein endothelium
... Immunohistochemistry; vWf: Von Willebrand factor; eNOS: Nitric oxide synthase; EVH: Endoscopic vein harvesting; OVH: Open vein harvesting; CABG: Coronary artery bypass graft; CAD: Coronary ...
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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von willebrand multimers and ADAMTS13 inhibition
... glycoprotein von Willebrand factor (VWF) and its propeptide, both of which are indices of endothelial cell ...plasma VWF antigen (VWF:Ag) level is associated with disproportionately ...
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Time course of soluble P-selectin and von Willebrand factor levels in trauma patients: a prospective observational study
... This study has several limitations. Since initial samples were collected after admission to the ICU, the impacts of emergency treatments prior to admission on coagula- tion markers had not been evaluated, for example, ...
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Variance of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) concentrations in activated, concentrated platelets from healthy male donors
... The selected biomarkers represent a small fraction of all biologically active molecules released from platelets and must be considered during interpretation of this study. The platelet proteome variation is known to ...
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Von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal plasma von Willebrand factor
... The vWf was isolated from the plasma of one of these ...purified vWf induced platelet aggregation of normal platelets resuspended in either normal or severe vWd plasma, but the vWf did not induce ...
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Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings.
... while VWF strings are clearly tethered to the endothelium, the majority of the strings appeared to be distanced from, and not in direct contact with, the endothelial monolayer along much of their ...
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Fibrin induces release of von Willebrand factor from endothelial cells
... reptilase. Metabolically labeled vWf was immunopurified from the medium after release by fibrin and shown to consist of highly processed protein lacking pro-vWf subunits. The contribution of residual ...
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Relationship between ABO blood group and von Willebrand factor levels: from biology to clinical implications
... protect VWF from proteolytic degradation in plasma [36], the recent literature data show that a reduc- tion in the number of sugars on the oligosaccharide chains of VWF is associated with an increased ...
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Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow
... of von Willebrand factor (vWF) antigen and vWF multimeric forms larger than those present in normal plasma, was the red blood cell (RBC)-suspending medium instead of serum-free medium ...
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Abstract
... and von Willebrand factor (vWF), secreted from the ...6]. vWF is also produced by endothelium and is also a marker of endothelial dysfunction in several vas− cular and non−vascular ...
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O linked carbohydrate of recombinant von Willebrand factor influences ristocetin induced binding to platelet glycoprotein 1b
... the vWf-glycoprotein 1b interaction promoted by ristocetin and suggest that abnormalities in carbohydrate modification might contribute to the altered ristocetin-dependent reactivity between vWf and ...
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Gray platelet syndrome Dissociation between abnormal sorting in megakaryocyte alpha granules and normal sorting in Weibel Palade bodies of endothelial cells
... Since the Weibel-Palade bodies WPB of endothelial cells as well as the a-granules contain the von Willebrand Factor vWF and P-selectin, we examined by transmission electron microscopy th[r] ...
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Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets
... platelets. Binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. Binding of 125I-FVIII/vWF to platelets can be competitively inhibited by unlabeled ...
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Subunit composition of plasma von Willebrand factor Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE)
... plasma vWF from 25 normal individuals. The vWF polypeptides were detected by immunoblotting with a mixture of 55 anti-vWF monoclonal antibodies followed by 125I-rabbit anti-mouse antibody and ...
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Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin Role of platelet activation, fibrinogen, and two distinct membrane receptors
... of vWF to GPIb, even in the absence of ristocetin, results in platelet-platelet interaction that is followed by exposure of the GPIIb/IIIa receptors for adhesive ...by vWF binding to ...normal vWF ...
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