Wharton's jelly
Comparison of biological characteristics of mesenchymal stem cells derived from maternal-origin placenta and Wharton’s jelly
... Most often MSCs are transplanted for tissue repair and regeneration. Due to their immunomodulatory properties, MSCs have garnered increasing research at- tention in recent years. MSCs have been used for treat- ing ...
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EVALUATION OF FETAL WEIGHT SONOGRAPHICALLY USING AREA OF WHARTON'S JELLY AND MORPHOLOGY OF UMBILICAL CORD
... The relation of gestational age and AWJ during pregnancy showed a R²=0.886 and an adjusted R²=0.881. ANOVA analysis showed F=2413.28 and a p<0.0001. This shows a very strong correlation between the AWJ and gestational ...
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Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing
... transfer of extracellular vesicles (EVs), such as exosomes [32]. Exosomes are a form of extracellular vesicle. Exosomes are saucer-shaped vesicles between 30 and 100 nm in diameter; they are surrounded by a lipid bilayer ...
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Sertoli cell-mediated differentiation of male germ cell-like cells from human umbilical cord Wharton’s jelly-derived mesenchymal stem cells in an in vitro co-culture system
... Wharton's jelly-derived mesen- chymal stem cells (HUMSCs) are multipotent stem cells with specific mesenchymal characteristics that can be in- duced to generate different tissues or cells, such as Schwann cells ...
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
... Wharton’s jelly contains significant amounts of HA [31]. Moreover, it is well known that scaffold composed of HA may create an environment that can preserve the normal phenotype of chondrocytes and may guide cell ...
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Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells
... marrow, Wharton ’ s jelly (WJ), adipose tissue, umbilical cord blood, and placenta have been tested in various pre- clinical models of fibrosis ...
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Evaluating the Cartilage-Specific Genes Expression in Co-culture of Chondrocytes With 2 Different Mesenchymal Stem Cells: Adipose and Wharton"s Jelly Derived
... Wharton’s jelly with superior properties compared to ASCs in terms of proliferation rate, stemness characteristics, and tolerance in allograft transplantation ...Wharton’s jelly enhanced the expression of ...
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Management of retinitis pigmentosa by Wharton’s jelly derived mesenchymal stem cells: preliminary clinical results
... Mesenchymal stem cells (MSCs) are well known for secreting a broad range of regenerative, anti- inflammatory, anti-apoptotic and anti-fibrotic factors. These factors include NGF, BDNF, CNTF and glial- derived ...
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Intravenous infusion of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells as a potential treatment for patients with COVID-19 pneumonia
... Mesenchymal stem cells (MSCs) have been widely used to treat autoimmune disease, graft-versus-host disease (GVHD), and other diseases with very good safety [10, 11]. MSCs play a positive role in immunomodulatory effects ...
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Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton’s jelly mesenchymal stem cells
... Multi- lineage differentiation of human umbilical cord Wharton ’ s Jelly mesenchymal stromal cells mediates changes in the expression profile of stemness markers.. Mesenchymal stem cells[r] ...
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Wharton’s jelly mesenchymal stem cell-based or umbilical vein endothelial cell-based serum-free coculture with cytokines supports the ex vivo expansion/maintenance of cord blood hematopoietic stem/progenitor cells
... cells reached confluence. Isolated UVECs were seeded in 25-cm 2 tissue culture flasks or culture dishes and culti- vated in EBM medium. The primary cells were detached with trypsin-EDTA (0.25%) (HyClone Laboratories Lo- ...
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Overexpression of apelin in Wharton’ jelly mesenchymal stem cell reverses insulin resistance and promotes pancreatic β cell proliferation in type 2 diabetic rats
... Wharton’ s jelly-derived mesenchymal stem cells (WJ- MSCs) are a primitive stromal cell population and have been isolated from a continuum from the sub-amnion to the perivascular region of the ...
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Mesenchymal stem/stromal cells—a key mediator for regeneration after perinatal morbidity?
... Stem cells are broadly defined as cells with self-renewing and differentiation capacity. Although stem cells derived from embryonic tissue were identified first, the clinical use is limited due to ethical concerns and ...
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Effects of Wharton's jelly-derived mesenchymal stem cells on neonatal neutrophils
... Background: Mesenchymal stem cells (MSCs) have been proposed as autologous therapy for inflammatory diseases in neonates. MSCs from umbilical cord Wharton’s jelly (WJ-MSCs) are accessible, with high proliferative ...
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Umbilical cord-derived mesenchymal stromal cells: predictive obstetric factors for cell proliferation and chondrogenic differentiation
... ’ s modified Eagle ’ s medium; DMSO: Dimethylsulfoxide; EDTA: Ethylenediaminetetraacetic acid; FBS: Fetal bovine serum; FITC: Fluorescein isothiocyanate; HBSS: Hank ’ s balanced salt solution; HLA: ...
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Isolation, characterization, and gene expression analysis of Wharton’s jelly-derived mesenchymal stem cells under xeno-free culture conditions
... Wharton’s jelly-derived MSCs (WJ-MSCs), from the umbilical cord, have been shown to have faster proliferation rates and greater expansion capability compared with adult ...
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Velamentous Cord: A Dangerous Case Complicated by a Rural Population
... If the development of the placenta occurs improperly, a velamentous cord insertion (VCI) can occur. As the vessels course through the membranes, unprotected by the Wharton’s jelly, they are vulnerable to both ...
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Endocytic mechanisms and osteoinductive profile of hydroxyapatite nanoparticles in human umbilical cord Wharton’s jelly-derived mesenchymal stem cells
... Abbreviations: haPs, hydroxyapatite particles; hWJ-Mscs, human umbilical cord Wharton’s jelly-derived mesenchymal stem cells; np20, hydroxyapatite nanoparticles 20 nm in diameter; np80[r] ...
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Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis
... 4 Administration of primed Wharton ’ s jelly-derived mesenchymal stem cells (WJ-MSCs) significantly decreases immune cell infiltration in mice with Aspergillus fumigatus ( Af )-induced a[r] ...
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Quantification of the CM-Dil-labeled human umbilical cord mesenchymal stem cells migrated to the dual injured uterus in SD rat
... The Wharton ’ s jelly (WJ) was obtained by dissection and re- moval of the UC arteries, vein, and amniotic epithelium followed by three washes with sterile phosphate-buffered saline ...
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