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white matter hyperintensities (WMH)

FLAIR and Diffusion MRI Signals Are Independent Predictors of White Matter Hyperintensities

FLAIR and Diffusion MRI Signals Are Independent Predictors of White Matter Hyperintensities

... to WMH was continuous and significant at values far below the threshold used to segment the images at ...ment WMH (ie, ⫾ ...for white matter and FA values below the mean for white ...

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Original Article Periventricular rather than deep white matter hyperintensities are associated with white matter lesion relevant vascular cognitive impairment

Original Article Periventricular rather than deep white matter hyperintensities are associated with white matter lesion relevant vascular cognitive impairment

... Cerebral white matter hyperintensities (WMHs) are frequent findings on MRI in the ...in white matter le- sion relevant vascular cognitive impairment (VCI) ...(VaD). WMH volumes ...

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The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics

The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics

... of white matter hyperintensities (WMH) burden on motor outcomes among older individuals in the presence and absence of overt neurological conditions, and 2) to evaluate whether physical ...

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Whole blood gene expression and white matter Hyperintensities

Whole blood gene expression and white matter Hyperintensities

... of white matter, detectable as white matter hyperintensities (WMH) [1, ...these white matter lesions increases with aging [3 – 5], and they typically happen long ...

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Not All Age Related White Matter Hyperintensities Are the Same: A Magnetization Transfer Imaging Study

Not All Age Related White Matter Hyperintensities Are the Same: A Magnetization Transfer Imaging Study

... of WMH, defined as areas with increased signal intensity in the white matter compared with surrounding white ...as WMH when they showed no mass effect and could not be related to types ...

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White matter hyperintensities and self-reported depression in a sample of patients with chronic headache

White matter hyperintensities and self-reported depression in a sample of patients with chronic headache

... White matter hyperintensities (WMHs) appear as hyper- intense signals on T2-weighted magnetic resonance images (MRI) and represent ependymal loss and differing degrees of myelination in the brain [1, ...

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Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

... with white matter hyperintensities in a stroke population, and then examined whether genetic loci previously linked to WMHV in community populations are also associated in stroke ...

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Tractography at 3T MRI of Corpus Callosum Tracts Crossing White Matter Hyperintensities

Tractography at 3T MRI of Corpus Callosum Tracts Crossing White Matter Hyperintensities

... crossed white matter hyperintensities had decreased fractional anisotropy compared with tracts that did not pass through white matter hyperintensities (P ⫽ ...crossed ...

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Perivascular Spaces in Old Age: Assessment, Distribution, and Correlation with White Matter Hyperintensities

Perivascular Spaces in Old Age: Assessment, Distribution, and Correlation with White Matter Hyperintensities

... MATERIALS AND METHODS: This population-based study included 530 individuals who did not have dementia and were not institution- alized (age, ⱖ 60 years or older; mean age, 70.7 years; 58.9% women) who were living in ...

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Association of White Matter Hyperintensities with Low Serum 25 Hydroxyvitamin D Levels

Association of White Matter Hyperintensities with Low Serum 25 Hydroxyvitamin D Levels

... Patient profiles are shown in Table 1. Nine subjects were excluded because of incomplete MR imaging or confounding pathology (eg, brain tumor). Note the much higher incidence of black sub- jects in the low Vit D group ...

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APOE ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

APOE ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

... indeed WMH were associated with worse cognition more strongly in APOE-ε4 carriers than ...of WMH in carriers is CAA which might be more toxic than WMH caused by vascular compromise or ischemia due to ...

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Plasma NT-proBNP and white matter hyperintensities in type 2 diabetic patients

Plasma NT-proBNP and white matter hyperintensities in type 2 diabetic patients

... and WMH could also be brain to brain instead of heart to ...higher WMH and lower BPF, however no longer after adjustment for age and sex (Table ...that WMH is higher and BPF lower in our patients ...

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Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

... Epigenome-wide association analysis of WMH burden We examined the association of individual CpG probes with WMH burden in the 713 individuals with DNA methylation and brain MRI data. The association between ...

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Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities

Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities

... for WMH measured using Fazekas ...and WMH, depending on which WMH measure was used (all 3 WMH measures were statistically significant; table ...

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APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

... indeed WMH were associated with worse cognition more strongly in APOE «4 carriers than ...of WMH in carriers is CAA, which might be more toxic than WMH caused by vascular compromise or ischemia due ...

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Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

... described. WMH were segmented automat- ically using the combined T1 and T2 FLAIR data as input in the Brain Intensity Abnormality Classification Algorithm (BIANCA) ...for WMH detection that gives the ...

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Association of white matter hyperintensities with migraine features and prognosis

Association of white matter hyperintensities with migraine features and prognosis

... to WMH, migraine patients were divided into two groups: non-WMH group (complete absence of WMHs or WMH score = 0) and WMH group (the presence of WMHs or a WMH score of ≥ 1) (Table ...

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Cortical tau load is associated with white matter hyperintensities

Cortical tau load is associated with white matter hyperintensities

... Regional WMH were subject- ively rated, blinded to clinical diagnosis, by two experi- enced assessors ...related white matter change scale (ARWMC) [60]; score 0, absence of WMH; score 1, ...

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Longitudinal relaxographic imaging of white matter hyperintensities in the elderly

Longitudinal relaxographic imaging of white matter hyperintensities in the elderly

... Binary WMH masks were prepared after linear registration (6 degrees of freedom) [29] of skull-stripped FLAIR images to high resolution MPRAGE space followed by segmentation of WMHs based on man- ual seeding and ...

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Magnetization Transfer Ratio of White Matter Hyperintensities in Subcortical Ischemic Vascular Dementia

Magnetization Transfer Ratio of White Matter Hyperintensities in Subcortical Ischemic Vascular Dementia

... It is less clear why we did not find reduced MTR for the total volume of WMSH. Significant myelin loss observed in subjects with vascular dementia (16, 28, 31) should be associated with lower MTR measurements. While MTR ...

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