WILD-TYPE
The Resistant Population Cutoff (RCOFF): a New Concept for Improved Characterization of Antimicrobial Susceptibility Patterns of Non Wild Type Bacterial Populations
... the wild type from any population with at least one acquired resistance mechanism” or as “the upper MIC value of the wild-type distribution” (10, ...the wild-type populations ...
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Original Article Mutation status of ras genes in breast cancers with overexpressed p21Ras protein
... the wild type p21Ras overexpression induce proliferation and malig- nant transformation remains ...that wild type p21Ras can activate JAK2, either alone or together with the Wnt pathway, to ...
8
Suboptimal Enhancer Sequences Are Required for Efficient Bovine Leukemia Virus Propagation In Vivo: Implications for Viral Latency
... silencing of the LTR results from the presence of noncon- served CRE motifs associated with a reduction in the forma- tion of complexes between the TxREs and the CREB/ATF factors. Single CRE mutations, as well as their ...
12
Retrovirus Restriction by TRIM5 Proteins Requires Recognition of Only a Small Fraction of Viral Capsid Subunits
... of wild-type and G89V mutant CA proteins by transfection of cells with specific mixtures of the corresponding proviral ...the wild-type virus was strongly restricted, while the G89V mutant was ...
8
Density-Dependent Selection in Vesicular Stomatitis Virus
... its wild-type ancestor. We carried out competitions of MARM N and wild-type populations at different multiplicities of infection (MOIs) and initial ratios of the wild type to the ...
7
Phylogenetic analysis of the wild type strains of canine distemper virus circulating in the United States
... circulating wild-type CDV detected from various parts of the world possess different hemagglutinin (H) gene and protein sequences from the currently available modified live vaccines ...
10
Effect of Cleavage Mutants on Syncytium Formation Directed by the Wild-Type Fusion Protein of Newcastle Disease Virus
... on wild-type fusion ...the wild-type protein was determined by cotransfection of Cos cells with different ratios of wild-type and mutant ...of wild type assayed by ...
7
Evaluating the Allergic Risk of Genetically Modified Soybean
... inhibition percentages than the wild-type extract. IgE immunoblot analysis using sera from five patients (2, 8, 9, 10, and 13) showed strong reactivity to a 33-kDa band from the GM soybean extract. ...
8
Antibody Escape Kinetics of Equine Infectious Anemia Virus Infection of Horses
... The results of this study are consistent with earlier theoretical work by Coffin (39), which predicted that relatively small changes in selective pressure and viral fitness can result in rapid and pro- found changes in ...
7
Rous sarcoma virus direct repeat cis elements exert effects at several points in the virus life cycle.
... and wild type in steady-state RNA levels, we performed analyses in which transcription was blocked at zero time with dactinomycin and infected cell cultures were harvested at 3-h intervals after treatment ...
7
Viral suppression of multiple escape mutants by de novo CD8+T cell responses in a human immunodeficiency virus 1 Infected elite suppressor
... In this study we describe an ES whose immune system has selected for seven rare TW10 variants in Gag. The development of these variants was apparently due to the selective pressure placed on the virus by the CTL response ...
7
FOLFIRI plus panitumumab in the treatment of wild type KRAS and wild type NRAS metastatic colorectal cancer
... 7. Venook AP, Niedzwiecki D, Lenz H-J, Innocenti F, Mahoney MR, O'Neil BH, Shaw JE, Polite BN, Hochster HS, Atkins JN et al: CALGB/SWOG 80405: phase III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or ...
7
Epstein-Barr virus EBNA3C represses Cp, the major promoter for EBNA expression, but has no effect on the promoter of the cell gene CD21.
... Repression by EBNA3C tethered to DNA can be cell type specific, which suggests that it might require a corepressor. It has been suggested that GAL4-EBNA3C represses transcrip- tion by recruiting CBF1/RBP-J k to ...
11
Filaggrin stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis
... This study used DRS to quantify the whole transcriptome of atopic skin in a unique collection of pediatric AD skin biopsy specimens; it represents the largest collection of AD skin tran- scriptomes reported to date. Skin ...
10
Characterising the role of anterior gradient protein 2 in cell adhesion and metastasis
... 146 Further evidence for a role of extracellular AGR2 stems from studies of newt anterior gradient protein (nAG), a member of the anterior gradient family [601]. nAG is important for limb regeneration in the salamander, ...
333
Role of the PDZ Domain-Binding Motif of the Oncoprotein E6 in the Pathogenesis of Human Papillomavirus Type 31
... with wild-type HPV31 and two mutant genomes (A) Southern blot analysis of HFKs stably transfected with HPV31 wild-type, E6Val ⌬ , and E6ETQV ⌬ genomes following selection and expansion in ...
12
Residues of Human Cytomegalovirus DNA Polymerase Catalytic Subunit UL54 That Are Necessary and Sufficient for Interaction with the Accessory Protein UL44
... The observations that both UL54 and UL44 are essential for HCMV DNA replication (21–23) and that the UL54-UL44 interaction is specific (17) make this interaction an attractive drug target. Recently, it was reported that ...
10
Bovine Viral Diarrhea Virus: Prevention of Persistent Fetal Infection by a Combination of Two Mutations Affecting Erns RNase and Npro Protease
... a type I IFN response to viral infection represents a prerequisite for persistent infection ...of wild-type ncp virus XIKE-A, which was shown to infect fetuses at a high ...
12
Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development
... their dramatically shortened, deformed limbs (20). When chicken limbs are infected with an Ihh-producing retrovirus, bone collars are induced, despite suppression of hypertrophy of chondrocytes (19). Further, Ihh stim- ...
11
Genetic and biochemical studies of mitochondria in the yeast saccharomyces cerevisiae
... their wild type counterparts, over the same period of ...the wild type would not be enough to create the large differences in sugar ...
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