wild type human adenovirus type 5
Interaction of Adenovirus Type 5 Fiber with the Coxsackievirus and Adenovirus Receptor Activates Inflammatory Response in Human Respiratory Cells
... and 5 (Ad5), have been extensively studied for the transfer of therapeutic genes into different organs, aimed to the cure of monogenic diseases like cystic fibrosis or complex disorders such as cancer, since they ...
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Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis.
... B 0, Infection of monkey or human cells with type Mock-infected cell DNA binding proteins labeled with [3H]leucine; A, wild-type infected cell DNA 5 adenovirus results in the synthesis o[r] ...
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Lack of evidence of phenotypic complementation of E1A/E1B-deleted adenovirus type 5 upon superinfection by wild-type virus in the cotton rat.
... wt human Ad5 and two recombinant vectors, Ad- b -gal-nls (which contains ...of adenovirus were prepared and titrated by the infection of 293 ...with 5 m g of linearized pMLPA5- b -gal or 5 m g ...
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The human papillomavirus type 16 E7 protein complements adenovirus type 5 E1A amino-terminus-dependent transactivation of adenovirus type 5 early genes and increases ATF and Oct-1 DNA binding activity.
... mary human fibroblasts and BALB/c3T3 cells, these mutant E1A viruses complete the viral life cycle and form infectious virus particles in HeLa cells with efficiencies comparable to that of dl309 ...
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Low-Dose Adenovirus Vaccine Encoding Chimeric Hepatitis B Virus Surface Antigen-Human Papillomavirus Type 16 E7 Proteins Induces Enhanced E7-Specific Antibody and Cytotoxic T-Cell Responses
... pair 5 ⬘ -CTCGAGGATTGGGGA-3 ⬘ and 5 ⬘ -GATATCAATGT ...oligonucleotides 5 ⬘ -GATATCGAGG AGGACGAGATCGA-3⬘ and 5⬘-GATATCATGCACGGCGACA-3⬘, respec- tively, and the antisense oligonucleotide ...
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Transforming Potential of the Adenovirus Type 5 E4orf3 Protein
... encoding human wild-type PML (pCMV-PML) with pAd5 XhoI-C reduced the number of foci by over 60% compared with pAd5 XhoI-C ...(Fig. 5), we also exam- ined whether simultaneous expression of ...
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Human Adenovirus Type 5 Induces Cell Lysis through Autophagy and Autophagy-Triggered Caspase Activity
... in wild-type (wt) but not in ATG5 ⫺/⫺ MEFs, as indicated by conversion of LC3-I to LC3-II ...in human glioma U-87 MG cells ...in adenovirus-mediated cell ...
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Development and Characterization of Bovine × Human Hybrid Cell Lines That Efficiently Support the Replication of both Wild-Type Bovine and Human Adenoviruses and Those with E1 Deleted
... transforming human embryonic kidney cells with human adenovirus type 5 (HAV5) early region 1 (E1) sequences is an excellent host for generating and growing HAV5 recombi- nants with E1 ...
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Contrasting Effects of Human, Canine, and Hybrid Adenovirus Vectors on the Phenotypical and Functional Maturation of Human Dendritic Cells: Implications for Clinical Efficacy
... canine adenovirus serotype 2 (CAV-2) vectors in the clinical setting by assaying their effect on human monocyte- derived DC ...to human adenovirus (HAd) vectors containing the ...
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Constructing chimeric type 12/type 5 adenovirus E1A genes and using them to identify an oncogenic determinant of adenovirus type 12.
... The resultant Adl2-based chimeric viruses, ch702 and ch704, in which the spacer region is replaced with in-frame type 5 sequence, grow normally on human A549 cells and display wild-type [r] ...
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Postentry Neutralization of Adenovirus Type 5 by an Antihexon Antibody
... of adenovirus (Ad), are an important component of the neutralizing activity in serum from naturally infected humans and experimentally infected ...Ad type 5 (Ad5) were screened for antihexon binding ...
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Intracellular Uncoating of Type 5 Adenovirus Deoxyribonucleic Acid
... After 1 hr, the second stage of uncoating was initiated by a newly synthesized "uncoating protein"; after 3 hr, 60 to 70%0 of the parental viral DNA was converted to a deoxyribonuclease-[r] ...
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Synthesis In Vitro of Type 5 Adenovirus Capsid Proteins
... Immunological precipitation of in vitro synthesized proteins by antisera to specific structural proteins of type 5 adenovirus Reaction mixturea containing infected cell material Antiseru[r] ...
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Promyelocytic leukemia protein isoform II inhibits infection by human adenovirus type 5 through effects on HSP70 and the interferon response
... Atwan, Zeenah, Wright, Jordan L., Leppard, Keith and Woodman, Andrew. (2016) Promyelocytic leukemia protein isoform II inhibits infection by human adenovirus type 5 through effects on HSP70 ...
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Adenovirus-specific DNA-binding protein inhibits the hydrolysis of DNA by DNase in vitro.
... Adenovirus H5 wild type or ts125 2 was Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The adenovirus-specific DNA-binding protein was isolated from adenovirus type 5-i[r] ...
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Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat.
... To further map the sequences responsible for repression in E1A1-80, E1A1-80 D 4-25, E1A1-80 D 30-49, and E1A1-80 D 70- 80 were tested for the ability to repress HIV LTR transcription in vitro. As shown in Fig. 3A, ...
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Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.
... A weaker affinity of mutants M310, M374, and M392 for HLA antigens caused by structural rearrangements of the proteins and/or lower concentrations of these mutants in the ER caused by tr[r] ...
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Defective Virions in Human Adenovirus Type 12
... Preparations of oncogenic human adenovirus type 12 Adl2 were shown to contain a high proportion of virions which, although capable of cell killing, are unable to form plaques or to induc[r] ...
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The expression and function of the adenovirus type 5 E4 region
... Adenovirus early region 4 encodes .functions required for efficient DNA replication, late gene expression, and host cell shutoff.. Adenovirus early region 4 encodes two gene products wit[r] ...
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Acetylation of histone-like proteins of adenovirus type 5.
... The sequence of the precursor portion of pVII has not been determined due to the presence of a blocked amino acid at the amino terminus, which is not available for dansylation or reactio[r] ...
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